Portal blood flow during and after high-intensity physical exercise in rats: response of plasma endothelin-1 and catecholamine

Yano, Lisa; Yano, Hiromi; Taketa, Kazuhisa

doi:10.1016/s1386-6346(98)00012-6

Cited by 6 publications

(5 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similarly, in a randomized clinical trial significant decrease in abdominal visceral fat was observed in overweight women following 12 weeks of HIIT (Zhang et al 2015). There may be several mechanisms underlying this training-induced body weight/fat loss effect observed in human (Boutcher 2011;Terada et al 2004) and animal studies (Katch et al 1979;Yano et al 1998;Panveloski-Costa et al 2012). These include increased whole body and skeletal muscle capacity for fatty acid oxidation and decreased post-training appetite (Boutcher 2011;Terada et al 2004;Katch et al 1979).…”

Section: Discussionmentioning

confidence: 99%

“…These include increased whole body and skeletal muscle capacity for fatty acid oxidation and decreased post-training appetite (Boutcher 2011;Terada et al 2004;Katch et al 1979). For the HIIT group, it is suggested that generated catecholamines or the need to remove lactate and H+ and to resynthesize glycogen could be the mechanism influencing post exercise fat oxidation (Boutcher 2011;Panveloski-Costa et al 2012;Yano et al 1998). In addition, lower liver weight was observed in the LIT group compared to the CTL and SED groups.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Light-intensity and high-intensity interval training improve cardiometabolic health in rats

Batacan

Duncan

Dalbo

et al. 2016

Appl. Physiol. Nutr. Metab.

View full text Add to dashboard Cite

Physical activity has the potential to reduce cardiometabolic risk factors but evaluation of different intensities of physical activity and the mechanisms behind their health effects still need to be fully established. This study examined the effects of sedentary behaviour, light-intensity training, and high-intensity interval training on biometric indices, glucose and lipid metabolism, inflammatory and oxidative stress markers, and vascular and cardiac function in adult rats. Rats (12 weeks old) were randomly assigned to 1 of 4 groups: control (CTL; no exercise), sedentary (SED; no exercise and housed in small cages to reduce activity), light-intensity trained (LIT; four 30-min exercise bouts/day at 8 m/min separated by 2-h rest period, 5 days/week), and high-intensity interval trained (HIIT, four 2.5-min work bouts/day at 50 m/min separated by 3-min rest periods, 5 days/week). After 12 weeks of intervention, SED had greater visceral fat accumulation (p < 0.01) and slower cardiac conduction (p = 0.04) compared with the CTL group. LIT and HIIT demonstrated beneficial changes in body weight, visceral and epididymal fat weight, glucose regulation, low-density lipoprotein cholesterol, total cholesterol, and mesenteric vessel contractile response compared with the CTL group (p < 0.05). LIT had significant improvements in insulin sensitivity and cardiac conduction compared with the CTL and SED groups whilst HIIT had significant improvements in systolic blood pressure and endothelium-independent vasodilation to aorta and mesenteric artery compared with the CTL group (p < 0.05). LIT and HIIT induce health benefits by improving traditional cardiometabolic risk factors. LIT improves cardiac health while HIIT promotes improvements in vascular health.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Light-intensity and high-intensity interval training improve cardiometabolic health in rats

Batacan

Duncan

Dalbo

et al. 2016

Appl. Physiol. Nutr. Metab.

View full text Add to dashboard Cite

show abstract

“…Plasma adrenaline, noradrenaline and dopamine were determined by automated high-performance liquid column chromatography at the Okayama Medical Laboratory [19] . TNF-␣ was measured by an enzyme-linked immunosorbent assay (ELISA) using a commercially available kit (BioSource International, Camarillo, Calif., USA).…”

Section: Animalsmentioning

confidence: 99%

Beta-Adrenergic Receptor Blockade Attenuates the Exercise-Induced Suppression of TNF-Alpha in Response to Lipopolysaccharide in Rats

Kitamura

Shiva

Woods

et al. 2007

Neuroimmunomodulation

View full text Add to dashboard Cite

Stressful exercise has been found to reduce the proinflammatory cytokine response to lipopolysaccharide (LPS). In this study, we aimed to determine whether receptor antagonists for corticosterone or catecholamines would increase the LPS-induced tumor necrosis factor-α (TNF-α) response after exhaustive exercise. Female F344 rats were randomly assigned to one of five groups: control (vehicle), RU-486 (glucocorticoid receptor antagonist, 30 mg/kg)-, propranolol [nonselective β-adrenergic receptor (AR) blockade, 30 mg/kg]-, atenolol (β₁-AR blockade, 30 mg/kg)-, or ICI 118551 (β₂-AR blockade, 30 mg/kg)-treated groups. Each antagonist was given intraperitoneally 30 min prior to exercise or control period. Exercised rats ran until exhaustion on a treadmill at gradually increasing speeds, from 10 to 36 m/min at 15% grade. Immediately postexercise or control period all rats were injected with LPS (1 mg/kg, i.v.). Plasma TNF-α was reduced by prior exercise to approximately 10% of that of sedentary controls (p < 0.01). Plasma TNF-α concentration in exercised RU-486-treated rats was significantly different than that of nonexercised rats (19.2%, p < 0.01) and not different from exercised rats. However, pretreatment of rats with the nonselective β-AR blocker propranolol almost completely reversed the exercise-induced suppression of plasma TNF-α in response to LPS. β₁-AR pretreatment almost completely attenuated the exercise-induced suppression of LPS-induced plasma TNF-α while β₂-antagonism had a partial effect. These results indicate that exercise-induced catecholamines, acting through β-ARs (especially the β₁-AR), are responsible for the exercise-induced suppression of plasma TNF-α after LPS administration.

show abstract

“…Exercise induced a slight increase in plasma ALT, AST and GU activities. The elevations of ALT and AST were not sufficient to estimate damage to the liver in the presence of muscle damage, but the increase in GU that was found in hepatocytes affected not only muscle cells but also hepatocytes (Yano et al. 1998).…”

Section: Hepatic Function During Acute Exercisementioning

confidence: 99%

Effects of acute moderate exercise on the phagocytosis of Kupffer cells in rats

Yano

Kinoshita

Kira

2004

Acta Physiologica Scandinavica

View full text Add to dashboard Cite

show abstract

Portal blood flow during and after high-intensity physical exercise in rats: response of plasma endothelin-1 and catecholamine

Cited by 6 publications

References 32 publications

Light-intensity and high-intensity interval training improve cardiometabolic health in rats

Light-intensity and high-intensity interval training improve cardiometabolic health in rats

Beta-Adrenergic Receptor Blockade Attenuates the Exercise-Induced Suppression of TNF-Alpha in Response to Lipopolysaccharide in Rats

Effects of acute moderate exercise on the phagocytosis of Kupffer cells in rats

Contact Info

Product

Resources

About