Portable detection of clenbuterol using a smartphone-based electrochemical biosensor with electric field-driven acceleration

Dou, Yanzhi; Jiang, Z.N.; Deng, Wangping; Su, Jing; Chen, Shixing; Song, Haiyun; Aldalbahi, Ali; Zuo, Xiaolei; Song, Shiping; Shi, Jiye; Chen, Fan

doi:10.1016/j.jelechem.2016.04.022

Cited by 54 publications

(24 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Dou et al [ 27 ] described a biosensing system for the detection of clenbuterol (CLB), using a mobile electrochemical device with an electric field-driven acceleration strategy. CLB has been illegally used in livestock raising to improve growth rate, reduce fat deposition and increase protein accretion.…”

Section: Resultsmentioning

confidence: 99%

Smartphone-Based Food Diagnostic Technologies: A Review

Rateni

Dario

Cavallo

2017

Sensors

242

144

View full text Add to dashboard Cite

A new generation of mobile sensing approaches offers significant advantages over traditional platforms in terms of test speed, control, low cost, ease-of-operation, and data management, and requires minimal equipment and user involvement. The marriage of novel sensing technologies with cellphones enables the development of powerful lab-on-smartphone platforms for many important applications including medical diagnosis, environmental monitoring, and food safety analysis. This paper reviews the recent advancements and developments in the field of smartphone-based food diagnostic technologies, with an emphasis on custom modules to enhance smartphone sensing capabilities. These devices typically comprise multiple components such as detectors, sample processors, disposable chips, batteries and software, which are integrated with a commercial smartphone. One of the most important aspects of developing these systems is the integration of these components onto a compact and lightweight platform that requires minimal power. To date, researchers have demonstrated several promising approaches employing various sensing techniques and device configurations. We aim to provide a systematic classification according to the detection strategy, providing a critical discussion of strengths and weaknesses. We have also extended the analysis to the food scanning devices that are increasingly populating the Internet of Things (IoT) market, demonstrating how this field is indeed promising, as the research outputs are quickly capitalized on new start-up companies.

show abstract

Section: Resultsmentioning

confidence: 99%

Smartphone-Based Food Diagnostic Technologies: A Review

Rateni

Dario

Cavallo

2017

Sensors

242

144

View full text Add to dashboard Cite

show abstract

“…Several attempts have been made to develop cell phones as a user interface for point-of-care devices (Ainla et al 2018; Dou et al 2016; Jiang et al 2014; Salomon et al 2014). A separate piece of hardware couples to the sensor while the smart phone controls measurement parameters and displays results through custom applications.…”

Section: Discussionmentioning

confidence: 99%

POISED-5, a portable on-board electrochemical impedance spectroscopy biomarker analysis device

Sawhney

Conlan

2019

Biomed Microdevices

View full text Add to dashboard Cite

Point-of-care medical devices offer the potential for rapid biomarker detection and reporting of medical conditions, thereby bypassing the requirements for offline clinical laboratory facilities in many cases. Label-free electrochemical techniques are suitable for use in handheld diagnostic devices due the inherent electronic detection modality and low requirement for processing reagents. While electrochemical impedance sensing is widely used in tissue analysis such as body composition measurement, its use in point-of-care patient testing is yet to be widely adopted. Here we have considered a number of issues currently limiting the translation of electrochemical impedance sensing into clinical biosensor devices. Specifically, we have addressed the current requirement for these sensors to be connected to an external processor by applying a minimum number of frequencies required for optimized biomarker detection, and subsequently delivering analytics within the measurement device. The POISED-5 device was evaluated using a sensor for the ovarian cancer biomarker cancer antigen 125 (CA125), demonstrating performance comparable to standard laboratory equipment, with direct interpretation of response signal amplitude substituting traditional impedance component calculation and model fitting.

show abstract

“…As shown in Figure , proprietary ports such as USB or Apple's lightning port have been widely used both to provide power to the periphral and to send bidirectional data . Typically, no additional power source other than the phone is required in this case removing the hassle of charging or replacing an extra battery, which ideally would improve patient adherence to testing.…”

Section: Integration With Smartphonementioning

confidence: 99%

Point‐of‐Care Smartphone‐based Electrochemical Biosensing

Sun

Hall

2018

Electroanalysis

View full text Add to dashboard Cite

Point‐of‐care (PoC) biosensors offer promising solutions to today's adverse and costly healthcare issues by moving diagnostic tools closer to the patient. The ubiquity of smartphones has brought about an emergence of PoC devices, which leverage the smartphone's capabilities, enabling the creation of low‐cost and portable biosensors. Electrochemical biosensors are well suited for PoC testing since the transducers can be miniaturized and inexpensively fabricated. This review paper discusses recent developments in smartphone‐based electrochemical biosensors for PoC diagnostics. These peripherals utilize the various connectivity options (for example proprietary ports, audio headphone‐jack, or wireless radio) to offload functionality to the smartphone. The smartphone‐based implementations of various electrochemical techniques, such as amperometry, potentiometry, and impedance spectroscopy are explored. Major challenges include reducing power, area, and cost of measurement circuitry, while maintaining adequate performance for PoC diagnostic applications.

show abstract

Portable detection of clenbuterol using a smartphone-based electrochemical biosensor with electric field-driven acceleration

Cited by 54 publications

References 34 publications

Smartphone-Based Food Diagnostic Technologies: A Review

Smartphone-Based Food Diagnostic Technologies: A Review

POISED-5, a portable on-board electrochemical impedance spectroscopy biomarker analysis device

Point‐of‐Care Smartphone‐based Electrochemical Biosensing

Contact Info

Product

Resources

About