Planejamento experimental na otimização da extração dos frutos de Syzygium cumini (L.) skeels

Migliato, Ketylin F.; Corrêa, Marcos Antônio; Salgado, Hérida Regina Nunes; Tognolli, João Olímpio; Sacramento, Luís Vitor Silva do; Mello, João Carlos Palazzo de; Mendes-Giannini, María José Soares; Almeida, Ana Marisa Fusco; Pizzolitto, Antônio Carlos

doi:10.1590/s0100-40422011000400024

Cited by 16 publications

(8 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Dados da literatura revelam que é muito mais provável encontrar atividade biológica em plantas orientadas pelo seu uso na medicina popular (etnofarmacologia) do que em plantas escolhidas ao acaso (Migliato et al, 2011).…”

Section: Introductionunclassified

Determinação dos compostos fenólicos e da capacidade antioxidante de extratos aquosos e etanólicos de Jambolão (Syzygium cuminiL.)

Veber

Petrini

Andrade

et al. 2015

Rev. bras. plantas med.

View full text Add to dashboard Cite

RESUMO:A espécie Syzygium cumini conhecida como Jambolão é uma das plantas mais utilizadas na medicina popular principalmente no tratamento de febre, estomalgia, gastropatia e diabetes mellitus tipo 2. O rendimento extrativo de compostos bioativos, e mesmo sua propriedade farmacológica, no caso, a capacidade de desativação de radicais livres, são influenciados pelo método e solvente utilizados. No presente estudo foi avaliado o efeito de extração aquosa a quente e a frio, e as extrações hidroalcoólicas em quatro diferentes concentrações de etanol, de folhas e frutos de Jambolão em diferentes estágios de maturação. A quantificação de compostos fenólicos dos extratos foi realizada pelo método de Folin-Ciocalteau, enquanto o método para avaliar a atividade antirradical livre foi realizado através da capacidade de desativação do radical DPPH ABSTRACT: Determination of phenolic compounds and antioxidant capacity of aqueous and ethanolic extracts of Jambul (Syzygium cumini).The species Syzygium cumini, known as Jambul, is one of the most used species in folk medicine because of the possible anti-inflammatory and hypoglycemic activity from its extracts. Studies looking for bioactive compounds in several species have tested many extraction methods evaluating the capacity of sequestration of different types of compounds. In the present study, the effects of hot and cold extraction, as well as hydroalcoholic extraction at four different concentrations were evaluated, using as plant material leaves and fruits at different stages of maturation. The content of phenolic compounds of the obtained extracts was evaluated by the Folin-Ciocalteu method, as well as the antiradical activity by the DPPH • scavenging capacity. Analyzing the five different stages of fruit ripening compared to leaves, it was observed that the leaves had higher averages in the amounts of phenolic compounds (237.52 mg GAE 100 g -1 ) compared to the fruit, being the greenest fruit the one that had the highest amount of phenolic compounds (109.17 mg GAE 100 g -1 ) when compared to the other stages of maturation tested. The extraction using 50% ethanol showed the best phenol results regardless of the plant material used. The antioxidant activity in the best results for phenols showed a higher antioxidant activity for green fruits (IC 50 2.27 mg.mL -1 ) compared to the leaves (IC 50 23.07 mg.mL -1 ) regardless of the extract type used.

show abstract

Section: Introductionunclassified

Determinação dos compostos fenólicos e da capacidade antioxidante de extratos aquosos e etanólicos de Jambolão (Syzygium cuminiL.)

Veber

Petrini

Andrade

et al. 2015

Rev. bras. plantas med.

View full text Add to dashboard Cite

show abstract

“…One of the possible causes of the extraction does not reach a peak, is related to the particle size of the plant matrix. According to Migliato et al (2011), the granulometric standardization of the ground material is important in the extraction process because particles with homogeneous dimensions increase the contact area between the solid material and the extractor liquid. In addition, reducing particle size using a knife or ball mill could assist with mass transfer, improving extraction yield in a shorter time.…”

Section: Resultsmentioning

confidence: 99%

Antioxidant and Antimicrobial Properties of Eucalyptus Leaf Extract Obtained Using Pressurized Ethanol / Propriedades Antioxidantes E Antimicrobianas Do Extrato De Folhas De Eucalipto Obtidos Com Etanol Pressurizado

Fischer

Gowzdz

Feltes

et al. 2020

BJD

View full text Add to dashboard Cite

Eucalyptus leaves are a secondary product of wood production. The pressurized liquid extraction (PLE) technique is an attractive process due to its advantages. The objective of this work was to obtain extracts of Eucalyptus saligna leaves using the PLE technique, and to characterize different extraction time fractions in relation to bioactive compounds and antioxidant and antimicrobial activities. The extraction of E. saligna leaves was carried out in a jacketed extractor at 40 °C, pressure of 10.4 MPa, with a solvent flow of 2.5 mL.min-1 , using 95% ethanol. The system remained pressurized for 30 minutes in static extraction, followed by 180 minutes in dynamic extraction. The levels of total phenols, flavonoids, antioxidant activity and antimicrobial potential against Staphylococcus aureus and Escherichia coli were evaluated. The extraction showed an overall yield of 12.3% after 180 minutes. The total concentrations of phenols and flavonoids were 618.57 mgGAE.g-1 and 160.28 mgQE.g-1 respectively. The extracts showed good antioxidant and antimicrobial potential, with IC50 between 0.016 and 0.043 mg.mL-1 , and MIC against S. aureus and E. coli between 0.313 and 1.25 mg.mL-1. PLE demonstrated efficiency in obtaining extracts of E. saligna leaves with bioactive properties.

show abstract

“…It is important to highlight that the use of solvents with different polarities in obtaining the extracts reflects the composition of the secondary metabolites found, which justify the differences regarding the antimicrobial activity of the extracts (MIGLIATO et al, 2011). With this, it was verified that the extracts with the solvent with greater polarity (EtOH and MeOH) proved to be efficient in the antimicrobial action, in relation to the others.…”

Section: Chemical Compoundsmentioning

confidence: 87%

Biological activities and phytochemical screening of leaf extracts from Zanthoxylum caribaeum L. (Rutaceae)

et al. 2020

View full text Add to dashboard Cite

The Brazilian flora is known for its vast biodiversity; however, many species have been still little studied regarding to their chemical composition and biological potential. Thus, this study aimed to determine the antimicrobial, antioxidant and acaricidal activity of the extracts of leaves of Zanthoxylum caribaeum L. In addition, phytochemical screening of these extracts was carried out to determine the main classes of secondary metabolites present in Z. caribaeum. Using the Z. caribaeum leaves, the aqueous extract and extracts were obtained in organic solvents (ethanol, methanol, hexane, acetone, dichloromethane and ethyl acetate). The antimicrobial activity of extracts was determined by broth microdilution method, and to detect antioxidant activity the method of capturing the free radical 2,2-diphenyl-1-picryl hydrazyl (DPPH) was used. The acaricidal activity of the extracts was tested on Dermanyssus gallinae (De Geer) (Acari: Dermanissidae). Ethanolic and methanolic extracts presented antimicrobial activity for most of the bacterial strains tested, as well as for yeast Candida albicans. The ethanolic extract presented high free radical sequestration potential (71.2%) and antioxidant capacity (the lowest IC50 value - 24.39 μg mL-1). The extracts obtained with methanol and acetone were the most promising. In general, phytochemical screening indicated the presence of steroids, flavanones, flavones, flavonols, saponins, tannins, triterpenoids and xanthones.

show abstract

Planejamento experimental na otimização da extração dos frutos de Syzygium cumini (L.) skeels

Cited by 16 publications

References 15 publications

Determinação dos compostos fenólicos e da capacidade antioxidante de extratos aquosos e etanólicos de Jambolão (Syzygium cuminiL.)

Determinação dos compostos fenólicos e da capacidade antioxidante de extratos aquosos e etanólicos de Jambolão (Syzygium cuminiL.)

Antioxidant and Antimicrobial Properties of Eucalyptus Leaf Extract Obtained Using Pressurized Ethanol / Propriedades Antioxidantes E Antimicrobianas Do Extrato De Folhas De Eucalipto Obtidos Com Etanol Pressurizado

Biological activities and phytochemical screening of leaf extracts from Zanthoxylum caribaeum L. (Rutaceae)

Contact Info

Product

Resources

About