Abstract:Persea americana Mill. seed or avocado seed contains phytochemical components such as flavonoids, tannins, saponins, phenolic, and alkaloid. The phenolic compounds of avocado seed are mainly catechin, hydroxybenzoic acid, caffeic acid, chlorogenic acid, coumaric acid, ferulic acid, and triterpenoid glycosides. This review also discusses various extraction methods using an organic solvent, inorganic solvent, and a mixture of solvents. The analysis methods to measure the chemical properties of extracted phytoche… Show more
“…PS(+)MS full scan of ethanol extract from peel of avocado can be found in Supplementary Materials, Figure S1 . It is reported that, as the avocado fruit develops, the carbohydrate amount decreases and the fatty acids and secondary metabolites content increases [ 46 , 47 ]. In ripe avocado fruits, the alkaloids constitute a remarkable percentage of the natural compounds present in the pulp [ 46 , 47 ].…”
Section: Resultsmentioning
confidence: 99%
“…It is reported that, as the avocado fruit develops, the carbohydrate amount decreases and the fatty acids and secondary metabolites content increases [ 46 , 47 ]. In ripe avocado fruits, the alkaloids constitute a remarkable percentage of the natural compounds present in the pulp [ 46 , 47 ]. From the alkaloids identified, anibine ( 1 ), duckeine ( 2 ), and anicanine ( 8 ) were not detected in PEL-ET.…”
Avocado (Persea americana) is a widely consumed fruit and a rich source of nutrients and phytochemicals. Its industrial processing generates peels and seeds which represent 30% of the fruit. Environmental issues related to these wastes are rapidly increasing and likely to double, according to expected avocado production. Therefore, this work aimed to evaluate the potential of hexane and ethanolic peel (PEL-H, PEL-ET) and seed (SED-H, SED-ET) extracts from avocado as sources of neuroprotective compounds. Minerals, total phenol (TPC), total flavonoid (TF), and lipid contents were determined by absorption spectroscopy and gas chromatography. In addition, phytochemicals were putatively identified by paper spray mass spectrometry (PSMS). The extracts were good sources of Ca, Mg, Fe, Zn, ω-6 linoleic acid, and flavonoids. Moreover, fifty-five metabolites were detected in the extracts, consisting mainly of phenolic acids, flavonoids, and alkaloids. The in vitro antioxidant capacity (FRAP and DPPH), acetylcholinesterase inhibition, and in vivo neuroprotective capacity were evaluated. PEL-ET was the best acetylcholinesterase inhibitor, with no significant difference (p > 0.05) compared to the control eserine, and it showed neither preventive nor regenerative effect in the neuroprotection assay. SED-ET demonstrated a significant protective effect compared to the control, suggesting neuroprotection against rotenone-induced neurological damage.
“…PS(+)MS full scan of ethanol extract from peel of avocado can be found in Supplementary Materials, Figure S1 . It is reported that, as the avocado fruit develops, the carbohydrate amount decreases and the fatty acids and secondary metabolites content increases [ 46 , 47 ]. In ripe avocado fruits, the alkaloids constitute a remarkable percentage of the natural compounds present in the pulp [ 46 , 47 ].…”
Section: Resultsmentioning
confidence: 99%
“…It is reported that, as the avocado fruit develops, the carbohydrate amount decreases and the fatty acids and secondary metabolites content increases [ 46 , 47 ]. In ripe avocado fruits, the alkaloids constitute a remarkable percentage of the natural compounds present in the pulp [ 46 , 47 ]. From the alkaloids identified, anibine ( 1 ), duckeine ( 2 ), and anicanine ( 8 ) were not detected in PEL-ET.…”
Avocado (Persea americana) is a widely consumed fruit and a rich source of nutrients and phytochemicals. Its industrial processing generates peels and seeds which represent 30% of the fruit. Environmental issues related to these wastes are rapidly increasing and likely to double, according to expected avocado production. Therefore, this work aimed to evaluate the potential of hexane and ethanolic peel (PEL-H, PEL-ET) and seed (SED-H, SED-ET) extracts from avocado as sources of neuroprotective compounds. Minerals, total phenol (TPC), total flavonoid (TF), and lipid contents were determined by absorption spectroscopy and gas chromatography. In addition, phytochemicals were putatively identified by paper spray mass spectrometry (PSMS). The extracts were good sources of Ca, Mg, Fe, Zn, ω-6 linoleic acid, and flavonoids. Moreover, fifty-five metabolites were detected in the extracts, consisting mainly of phenolic acids, flavonoids, and alkaloids. The in vitro antioxidant capacity (FRAP and DPPH), acetylcholinesterase inhibition, and in vivo neuroprotective capacity were evaluated. PEL-ET was the best acetylcholinesterase inhibitor, with no significant difference (p > 0.05) compared to the control eserine, and it showed neither preventive nor regenerative effect in the neuroprotection assay. SED-ET demonstrated a significant protective effect compared to the control, suggesting neuroprotection against rotenone-induced neurological damage.
“…Other seeds like those from avocado contain phytochemicals like flavonoids, alkaloids, saponins, tannins, etc. (Setyawan et al, 2021), which have antioxidant and antiinflammatory properties. Phenols in avocado seeds mainly include catechins, ferulic acid, coumaric acid, chlorogenic acid, caffeic acid, hydroxybenzoic acid, etc., with therapeutic and medicinal benefits (Setyawan et al, 2021).…”
Section: Seedsmentioning
confidence: 99%
“…(Setyawan et al, 2021), which have antioxidant and antiinflammatory properties. Phenols in avocado seeds mainly include catechins, ferulic acid, coumaric acid, chlorogenic acid, caffeic acid, hydroxybenzoic acid, etc., with therapeutic and medicinal benefits (Setyawan et al, 2021). Black seeds (Nigella sativa seeds) are also among excellent source of nutraceuticals (Kalonji, 2021), given the presence of trans-anethole, palmitic acid, oleic acid, linoleic acid, nigellidine, nigellicine, nigellimine N-oxide, nigellimine, etc (Kalonji, 2021).…”
Nutraceuticals play wide range of important roles, from health promotion, increasing life expectancy, maintaining body cell integrity, to reducing the risks of many diseases. As consumers continue to be attracted to nutraceuticals, such as superfoods, vegetables, fruits, high-protein foods, eating healthy intertwines with finding the right balance. Nowadays, the nutraceutical industries are among the many that target to meet the growing and dynamic consumers’ expectations. Adding to their increasing interest and general acceptability, consumers continue to be attracted to nutraceuticals. How nutraceuticals, especially functional foods, etc., help in tackling health challenges increase the interest among several researchers in this subject area, and given the ever-growing need across communities around the globe for healthy living, strengthens the need for continued synthesis of published information to supplement existing knowledge. This overview, therefore, discusses natural nutraceuticals, especially functional foods, their major bioactive components, formulation, health benefits for disease prevention.
“…The most recent review centered around the extraction and analysis methods for phytochemicals of avocado seeds, including their chemical and functional properties. 11 Some review papers explore the health effect of the seed, including antioxidant, anti-inflammatory, antihypertensive, cytotoxic, and immunomodulatory activities of avocado seeds from Hass, Fuerte, or drymifolia varieties. [12][13][14] Additionally, Colombo and Papetti processed avocado seeds to produce biofuel and explored the seeds' adsorption capacity to remove contaminants from water.…”
Avocado seed waste has increased as avocado products have become commercialized since the seed is considered inedible. However, by exploring the potential uses of the seed, the unrecyclable waste produced...
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