Phytochemical Screening and Bioactivity Studies of Endophytes Cladosporium sp. Isolated from the Endangered Plant Vateria Indica Using In Silico and In Vitro Analysis

Isaq, Mona; Somu, Prathap; Acharya, Diptikanta; Gomez, Levin Anbu; Thathapudi, Jesse Joel; Ramachandra, Y. L.; Rudraiah, Sunitha Bommanahalli; Ravi, Pooja; Padmalatha, S; Rosalin, Rosina; Poojari, Chandrappa Chinna; Lee, Yong Rok

doi:10.1007/s12010-022-03933-5

Cited by 5 publications

(2 citation statements)

References 26 publications

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“…The qualitative phytochemical investigation of the aqueous root extract of E racemosa was performed using standard tests with a slight modification [ [14] , [15] , [16] ].…”

Section: Methodsmentioning

confidence: 99%

Evaluations of the in vivo laxative effects of aqueous root extracts of Euclea racemosa L. in mice

2023

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“…The qualitative phytochemical investigation of the aqueous root extract of E racemosa was performed using standard tests with a slight modification [ [14] , [15] , [16] ].…”

Section: Methodsmentioning

confidence: 99%

Evaluations of the in vivo laxative effects of aqueous root extracts of Euclea racemosa L. in mice

2023

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“…Owing to improved living standards and the development and popularity of sustainable eco-agricultural systems, scientists are looking for safer and more effective ways to control plant diseases. Biocontrols such as the use of endophytic fungi producing bio-actives to reduce plant-pathogen invasions are one of the novel alternatives. , For example, several biocontrol agents have been commercialized to control rice sheath blight, like Bacillus and Streptomyces , which showed resistance to chemical exposure, radiation, desiccation, and nutritional deficit. − Biocontrol strategies are safer, environmentally friendly, and sustainable alternatives to chemical agents and hence have attracted much attention in recent years …”

Section: Introductionmentioning

confidence: 99%

Antibacterial Metabolites from Kiwi Endophytic Fungus Fusarium tricinctum, a Potential Biocontrol Strain for Kiwi Canker Disease

Dong

et al. 2023

J. Agric. Food Chem.

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Pseudomonas syringae pv. actinidiae (Psa) is a Gram-negative bacterium causing the kiwifruit canker disease, resulting in serious economic losses to the kiwifruit industry. This study investigated the use of an endophytic fungus, Fusarium tricinctum, obtained from the kiwi plant (Actinidia chinesis) as a potential biocontrol strain against the Psa. F. tricinctum showed an inhibition rate of 59.5% in vitro against Psa. Bioassay-guided isolation was conducted on the cultural broth of F. tricinctum and seven new imidazole alkaloids, (±)-fusaritricine J ((±)-1) and fusaritricines K-P (2−7), and four enniatins (8−11) were identified. Their absolute configurations were established through extensive spectroscopic methods, quantum chemical calculations, and X-ray single crystal diffraction. Compounds 1, 4, 5, and 8−11 showed comparable anti-bacterial activities against Psa as positive control, with MIC values of 25−50 μg/mL. Further cell membrane permeability assay suggested that the most active compound 4 could destroy the bacterial cell wall structure. Hence, F. tricinctum metabolites could be applied as potential anti-Psa agents, and F. tricinctum could be considered a biocontrol strain for the control of the kiwifruit canker disease.

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Endophytic fungi as a potential source of anti-cancer drug

Sonowal,

Gogoi,

Buragohain

et al. 2024

Arch Microbiol

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Phytochemical Screening and Bioactivity Studies of Endophytes Cladosporium sp. Isolated from the Endangered Plant Vateria Indica Using In Silico and In Vitro Analysis

Cited by 5 publications

References 26 publications

Evaluations of the in vivo laxative effects of aqueous root extracts of Euclea racemosa L. in mice

Evaluations of the in vivo laxative effects of aqueous root extracts of Euclea racemosa L. in mice

Antibacterial Metabolites from Kiwi Endophytic Fungus Fusarium tricinctum, a Potential Biocontrol Strain for Kiwi Canker Disease

Endophytic fungi as a potential source of anti-cancer drug

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