Antibacterial Metabolites from Kiwi Endophytic Fungus <i>Fusarium tricinctum</i>, a Potential Biocontrol Strain for Kiwi Canker Disease

Ma, Jin-Tao; Dong, Xin-Yue; Li, Zheng-Hui; Yan, Hongli; He, Juan; Liu, Ji-Kai; Feng, Tao

doi:10.1021/acs.jafc.3c00233

Cited by 7 publications

(5 citation statements)

References 46 publications

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“…This might indicate that these isolates have some beneficial functions in promoting plant growth. Both F. solani and F. tricinctum have been reported as potentially beneficial endophytic fungi in plants in responding to biotic stress [ 62 , 63 ].…”

Section: Discussionmentioning

confidence: 99%

Diversity and Pathogenicity of Fusarium Root Rot Fungi from Canola (Brassica napus) in Alberta, Canada

Yu,

Chang,

Fredua-Agyeman

et al. 2024

IJMS

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Root rot disease poses a significant threat to canola (Brassica napus), underscoring the need for a comprehensive understanding of its causal agents for more effective disease mitigation. The composition and diversity of fungal pathogens associated with root rot of canola in Alberta, Canada, were evaluated from plant tissue samples collected in 2021 and 2022. The study revealed Fusarium spp. as the predominant pathogens found in almost all surveyed fields. Fusarium avenaceum, F. redolens, and F. solani were among the most frequently recovered species. Greenhouse trials confirmed their pathogenicity, with F. avenaceum and F. sporotrichioides found to be particularly aggressive. Additionally, F. sporotrichioides and F. commune were identified for the first time as canola root rot pathogens. Inoculation with isolates of most species resulted in significant reductions in seedling emergence, plant height, and shoot and root dry weights. Analysis of translation elongation factor 1-α (TEF-1α) and internal transcribed spacer (ITS) sequences confirmed the identity of the Fusarium spp., while concatenating the ITS and TEF-1α sequences enabled improved species differentiation. Geographic and year effects did not influence fungal diversity or aggressiveness, as determined by principal component analysis. This study emphasized the high diversity and impact of Fusarium spp. in causing canola root rot.

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Section: Discussionmentioning

confidence: 99%

Diversity and Pathogenicity of Fusarium Root Rot Fungi from Canola (Brassica napus) in Alberta, Canada

Yu,

Chang,

Fredua-Agyeman

et al. 2024

IJMS

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“…Therefore, the potential of using MBCAs goes beyond their direct action against the target phytopathogen, as several bioactive compounds can be obtained from them. For example, isobenzofuranones and isocoumarins obtained from the fungus Paraphaeosphaeria sporulosa and imidazole alkaloids obtained from Fusarium tricinctum , both fungal species extracted epiphytically from healthy kiwifruit plants, have demonstrated capacity to inhibit the growth of Psa in plate assays ( Chen et al., 2022 ; Ma et al., 2022 ; Ma et al., 2023 ). Other bioactive compounds extracted from the fungus Zopfiella sp.…”

Section: State-of-the-art On Sustainable Disease Management Tools To ...mentioning

confidence: 99%

Scientific and technological advances in the development of sustainable disease management tools: a case study on kiwifruit bacterial canker

Santos,

Nunes da Silva,

Vasconcelos

et al. 2024

Front. Plant Sci.

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Plant disease outbreaks are increasing in a world facing climate change and globalized markets, representing a serious threat to food security. Kiwifruit Bacterial Canker (KBC), caused by the bacterium Pseudomonas syringae pv. actinidiae (Psa), was selected as a case study for being an example of a pandemic disease that severely impacted crop production, leading to huge economic losses, and for the effort that has been made to control this disease. This review provides an in-depth and critical analysis on the scientific progress made for developing alternative tools for sustainable KBC management. Their status in terms of technological maturity is discussed and a set of opportunities and threats are also presented. The gradual replacement of susceptible kiwifruit cultivars, with more tolerant ones, significantly reduced KBC incidence and was a major milestone for Psa containment – which highlights the importance of plant breeding. Nonetheless, this is a very laborious process. Moreover, the potential threat of Psa evolving to more virulent biovars, or resistant lineages to existing control methods, strengthens the need of keep on exploring effective and more environmentally friendly tools for KBC management. Currently, plant elicitors and beneficial fungi and bacteria are already being used in the field with some degree of success. Precision agriculture technologies, for improving early disease detection and preventing pathogen dispersal, are also being developed and optimized. These include hyperspectral technologies and forecast models for Psa risk assessment, with the latter being slightly more advanced in terms of technological maturity. Additionally, plant protection products based on innovative formulations with molecules with antibacterial activity against Psa (e.g., essential oils, phages and antimicrobial peptides) have been validated primarily in laboratory trials and with few compounds already reaching field application. The lessons learned with this pandemic disease, and the acquired scientific and technological knowledge, can be of importance for sustainably managing other plant diseases and handling future pandemic outbreaks.

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“…such as Bacillus subtilis against avocado rot caused by Colletotrichum and Cercospora in South Africa, and Aureobasidium pullulans against pome rot caused by Penicillium , Botrytis , and Monilinia in Austria . Our group has been conducting biocontrol studies for a long period, several potential biocontrol strains and a number of antipathogenic metabolites have been obtained, which have made great contributions to the disease control of kiwi and potato. − …”

Section: Introductionmentioning

confidence: 99%

Discovery of a Biocontrol Strain Trichaptum laricinum: Its Metabolites and Antifungal Activity against Pathogenic Fungus Colletotrichum anthrisci

Huang,

Yang,

et al. 2024

J. Agric. Food Chem.

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Finding safe and environmentally friendly fungicides is one of the important strategies in modern pesticide research and development. In this work, the antipathogenic effects of the fungus Trichaptum laricinum against the anthracnose pathogen Colletotrichum anthrisci were studied. The EtOAc extract of T. laricinum showed remarkable antifungal activity against C. anthrisci with an inhibition rate of 50% at 256 μg/mL. Bioguided isolation of the cultural broth of T. laricinum produced four new drimane sesquiterpenes, trichalarins A−D (1−4), and six other metabolites (5−10). Their structures were established by extensive spectroscopic methods, quantum chemical calculations, and single-crystal X-ray diffraction. All compounds exhibited antifungal activity against C. anthrisci with minimum inhibitory concentrations (MICs) of 8−64 μg/mL in vitro. Further in vivo assay suggested that compounds 2, 6, and 9 could significantly inhibit C. anthrisci growth in avocado fruit with inhibition rates close to 80% at the concentration of 256 μg/mL, while compounds 2 and 6 had an inhibition rate over 90% at the concentration of 512 μg/mL. The EtOAc extract of T. laricinum had no inhibitory effect on Pinus massoniana seed germination and growth at the concentration of 2 mg/mL, showing good environmental friendliness. Thus, the fungus T. laricinum could be considered as an ideal biocontrol strain, and its metabolites provided a diverse material basis for the antibiotic agents.

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Antibacterial Metabolites from Kiwi Endophytic Fungus Fusarium tricinctum, a Potential Biocontrol Strain for Kiwi Canker Disease

Cited by 7 publications

References 46 publications

Diversity and Pathogenicity of Fusarium Root Rot Fungi from Canola (Brassica napus) in Alberta, Canada

Diversity and Pathogenicity of Fusarium Root Rot Fungi from Canola (Brassica napus) in Alberta, Canada

Scientific and technological advances in the development of sustainable disease management tools: a case study on kiwifruit bacterial canker

Discovery of a Biocontrol Strain Trichaptum laricinum: Its Metabolites and Antifungal Activity against Pathogenic Fungus Colletotrichum anthrisci

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