Pediatric Urinary Tract Infection

Heffner, Viday; Gorelick, Marc H.

doi:10.1016/j.cpem.2008.09.009

Cited by 19 publications

(12 citation statements)

References 20 publications

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“…Urinary tract infections (UTIs) are one of the most common bacterial infections in humans both in the community and hospital setting [1] , which can affect any part of the genitourinary tract, including urethra, bladder, ureter, renal pelvis, or renal parenchyma [2] , and occur in all populations and ages. However, various factors including race, genetic factors, age, gender, sexual activity, nocturnal enuresis and circumcision in boys [3] , make infections range from presence of bacteria in urine without symptoms (asymptomatic bacteriuria) to wide spectrum of symptoms ranging from mild excitation to bacteremia, sepsis, or even death [4] . It is estimated that approximately 150 million cases occur globally each year [5] .…”

Section: Introductionmentioning

confidence: 99%

Bacterial Profile of Urinary Tract Infection and Antimicrobial Susceptibility Pattern Among Patients Attending at Bushra Medical Laboratory, Tripoli, Libya

Salem¹,

Ahmed²

2018

Journal of Gastroenterology and Hepatology Research

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BACKGROUND: Urinary tract infection (UTI) is a common infection that affects the urinary tract, particularly in women, children and elderly, and it doesn't always cause classic signs and symptoms. Excessive utilization of antibiotics led to increased incidence of antibiotic resistance among uropathogens worldwide. AIM: To identify the causative bacteria of UTI and antimicrobial susceptibility pattern among patients attended to Bushra Medical laboratory, Tripoli, Libya. METHODS: This prospective study was conducted in Tripoli city, on 1423 urine specimens from untreated patients with clinical symptoms of UTIs. Bacterial identification and antimicrobial susceptibility testing were done on 291 specimens which their colony count ≥ 10 5 colony forming units (cfu)/mL, using DL-96II (Auto microbial identification and antimicrobial susceptibility testing system). RESULTS: The prevalence of significant bacteriuria was 20.4% (291/1423), among them 81.4% (237/291) were females and 18.6% (54/291) were males. Just 0.7% (2/291) cases of isolated bacteria were gram positive cocci represented in Staphylococcus aureus, that exhibited hugely resistance to Penicillin (100%) and susceptible to many tested antimicrobial agents, while 99.3% (289/291) were gram negative bacilli represented in Klebsiella pneumonia 43.6% (127/291); Escherichia coli 33% (96/291); Klebsiella ozaenae 10.7% (31/291); Proteus mirabilis 9.3% (27/291); Pseudomonas mendocina 1.7% (5/291) and Pseudomonas alcaligenes 1% (3/291). Considering the results of this study, Klebsiella pneumonia isolates were the predominant pathogens in UTI. Except for Pseudomonas isolates, our data demonstrated that gram negative isolates were susceptible to Cefoperazone/Sulbactam followed by Ceftazidime then Levofloxacin (3.9%, 4.9% and 6% resistance, respectively), while Pseudomonas isolates were extremely sensitive to Amikacin, Piperacillin and Norfloxacin. CONCLUSION: Because of highly resistant bacteria to antibiotics, physicians must prescribe appropriate antibiotics depending on antibiotics susceptibility results. Otherwise, routine monitoring of antimicrobial resistance among uropathogens must be accomplished to guide the treatment of UTIs in the country.

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Section: Introductionmentioning

confidence: 99%

Bacterial Profile of Urinary Tract Infection and Antimicrobial Susceptibility Pattern Among Patients Attending at Bushra Medical Laboratory, Tripoli, Libya

Salem¹,

Ahmed²

2018

Journal of Gastroenterology and Hepatology Research

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“…Anatomic abnormalities include short urethra in females, urinary obstruction, Vesico ureteral reflux, neurogenic bladder which is the improper storage of urine in bladder and improper emptying of urine from bladder, and uncircumcised in boys. Uncircumcised boys have a great tendency to harbor organisms in the foreskin due to warm, moist and mucosal environment as a result bacteria migrate up to the urethra and colonize in the bladder (Dulczak and Kirk, 2005;Heffner and Gorelick, 2008).…”

Section: Introductionmentioning

confidence: 99%

Emergence of Metallo- β- Lactamase producing Isolates of Pseudomonas aeruogenosa Urinary Tract Infection in Children

Pambuk¹,

Salih²,

Mohammed³

2019

J Pure Appl Microbiol

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Citation: Chateen I. Ali Pambuk, Sabah M. Salih and Fatma Mustafa Mohammed, Emergence of Metallo-b-Lactamase producing Isolates of Pseudomonas aeruogenosa Urinary Tract Infection in Children, J Pure Appl Microbiol., 2019; 13(4):2309-2316. https:// AbstractInfections with Pseudomonas aeruginosa isolates producing Metallo-b-Lactamase (MBL) is a serious worldwide infections. It is associated with, higher mortality rates, more severe disease implicated and with a higher incidence of invasive disease than infections with the bacterial isolate of MBLnonproducers. This bacteria disseminated in many countries worldwide, with no reports available about their presence in Iraq. The present study was conducted to investigate the changes and the intensity of antibiotics resistance pattern of pediatric urinary tract infection (UTI) in duration of 2 years as well as reporting the first emergence of Metallo-b-Lactamase producing P aerugenosa in Iraq. Standard methods used for isolation and identification of bacteria. Carbapenem-resistance P. aeruginosa UTI isolates were tested for the presence of metallo-b-lactamases productino. This is the first report of the presence of Metallo-b-Lactamase producing P aerugenosa in Iraq region. The results showed no differences in resistance pattern among Gram positive bacteria isolated. While, their was a dramatic increase of Escherichia coli resistance which showed high sensitivity rate to cefotaxim (72.4%), recording an increasing rate of resistance by 12% during 2 years. Klebsiellae pneumoniae resistance profile were increased dramatically during 2 years to trimethoprim and cefotaxim to reach 30 % and 11% respectively, when compaired with our previous study. Regarding P. aeroginosae, there was further increase in resistance toward azithromycin, gentamicin and oxacillin by recording 14%, 11.6% and 11.6% of resistance rates respectively. The striking results of the present study was to find the resistant bacterial isolates of P. aeruginosae toward imipineme. Precisely, 4 (31.8%) out of 13 UTI isolates was found to be resistant to imipineme. In conclusion their was an different increasing resistance rates of isolates toward antibiotics, also an emergence of new MBL producing P. eaurogenosa.

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“…Rates of UTI vary markedly by sex, age and other patient characteristics and the reported incidence of UTI in different populations has also varied. The use of different methods of sample collection by the various investigators may contribute to this inconsistency [3].…”

Section: Introductionmentioning

confidence: 99%

Urine culture obtained from bag specimens and suprapubic aspiration in neonates

Hosseini

Ataei

Sharifzadeh

et al. 2015

J Pediatr Infect Dis

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Obtaining uncontaminated urine samples are important to diagnosis urinary tract infection in neonates. The present study was designed to compare urine contamination rates in two common methods of urine collection: urine bag versus suprapubic aspiration. In a cross-sectional study, 119 consecutive infants (aged 3 to 28 days) with fever who were referred to Children's Hospital Medical Center in Tehran between September 2004 and March 2005 were included. Urine was collected simultaneously by bag and suprapubic aspiration. The urine samples were analyzed and bacterial cultures performed using standard bacteriologic techniques. The rate of culture contamination differed markedly according to the method of urine culture. Suprapubic aspiration specimens were sterile in 92.4%. Pathogenic bacteria were isolated in 7.6%. No bacterial isolates were deemed to be contaminants. Only 8.5% of bag specimens were sterile. Of non-sterile cultures, 36.9% of bacterial isolates were deemed to be pathogenic and 54.6% contaminants (P < 0.001 vs. suprapubic aspiration). Pyuria (P = 0.002) and bacteriuria (P < 0.001) were more frequent in specimens obtained by bag than urine from suprapubic aspiration. The existence of a urinary tract anomaly was the main predictor for a positive culture in urine obtained by suprapubic aspiration. Contamination rates and rates of pyuria and bacteriuria are remarkably higher for urine obtained by bag specimens than for urine obtained by suprapubic aspiration.

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Pediatric Urinary Tract Infection

Cited by 19 publications

References 20 publications

Bacterial Profile of Urinary Tract Infection and Antimicrobial Susceptibility Pattern Among Patients Attending at Bushra Medical Laboratory, Tripoli, Libya

Bacterial Profile of Urinary Tract Infection and Antimicrobial Susceptibility Pattern Among Patients Attending at Bushra Medical Laboratory, Tripoli, Libya

Emergence of Metallo- β- Lactamase producing Isolates of Pseudomonas aeruogenosa Urinary Tract Infection in Children

Urine culture obtained from bag specimens and suprapubic aspiration in neonates

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