Paraneoplastic Syndromes Related to Lung Cancer

McClelland, Mary T.

doi:10.1188/10.cjon.357-364

Cited by 17 publications

(18 citation statements)

References 22 publications

(77 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The PNSs associated with lung cancer may have different initial manifestations, and small cell lung cancer tend to have much more PNSs than non-small cell lung cancer. The spectrum of clinical features ranges from mild systemic or cutaneous disease to hypercoagulability and severe neuromyopathic disorders (2). Involvement of the skin may proceed, or occur concurrently, or follow the detection of the tumor or metastasis.…”

Section: Discussionmentioning

confidence: 99%

Hyperpigmentation in palms associated with lung adenocarcinoma resolving after chemotherapy

Liu

et al. 2014

Clinical Respiratory J

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Hyperpigmentation in palms associated with lung adenocarcinoma resolving after chemotherapy

Liu

et al. 2014

Clinical Respiratory J

View full text Add to dashboard Cite

show abstract

“…IADHS symptoms rarely manifest when plasma sodium levels are higher than 125 mEq/L. Plasma sodium levels below 125 mEq/L may result in symptoms such as weakness, tiredness, nausea, headache, lethargy, and confusion, while levels below 120 mEq/L may lead to seizure and coma [39].…”

Section: Inappropriate Antidiuretic Hormone Syndromementioning

confidence: 99%

Paraneoplastic Syndromes in Lung Cancer

Taş¹

2018

Lung Cancer - Strategies for Diagnosis and Treatment

View full text Add to dashboard Cite

In recent years, the incidence of lung cancer (LC) has been increasing throughout the world and is the most common type of cancer in all regions of the world, occurring more frequently in men than in women. Paraneoplastic syndromes (PNS) refer to clinical conditions that develop in relation to tumors, without physical effects of the primary or metastatic tumors. The development of PNS is not associated with the size of the primary tumor or the extent of metastases. It is usually seen in small-cell lung cancer (SCLC) as well as other types of lung cancer. PNS developed in almost 1 in 10 patients with lung cancer and it may be an indicator for the diagnosis of lung cancer and it can be seen during later stages of cancer or at the time of cancer recurrence. Accordingly, the identification of these syndromes can be helpful in the early diagnosis of occult cancers, allowing timely treatment. PNS decreases the quality of life of the patients with cancer and thus requires specific treatment. Moreover, these conditions can be used as a marker of cancer activity and can predict prognosis. In this section, a detailed description of PNS is provided.

show abstract

“…Paraneoplastic syndromes can be associated with many types of cancer. 3 Acanthosis nigricans (AN) is one of the rare paraneoplastic syndromes associated with lung cancer. 2 In most cases, AN reflects metabolic disturbances seen in patients with obesity, metabolic syndrome, diabetes, or medications.…”

Section: Introductionmentioning

confidence: 99%

A case of acanthosis nigricans as a paraneoplastic syndrome with squamous cell lung cancer

Karakaş

Esin

Laçin

et al. 2016

OTT

View full text Add to dashboard Cite

A 55-year-old man presented with oral mucosal ulcers, blackening of both hands, and hyperpigmentation on axillary, anal, and inguinal regions for the last 3 months, which were all progressive. The patient was referred to the oncology department with the diagnosis of acanthosis nigricans for investigation of an underlying malignancy. He was a smoker. A computed tomography scan of thorax revealed enlarged mediastinal lymphadenopathies and a lesion on the left upper lobe. Fine-needle aspiration biopsy of the mediastinal lesion was consistent with squamous cell carcinoma, and biopsies of the skin and oral mucosal lesion also further confirmed the diagnosis of acanthosis nigricans. After docetaxel and cisplatin chemotherapy, a significant improvement in his skin and mucosal lesions was observed with almost complete resolution of the pulmonary lesion and the mediastinal lymph nodes.

show abstract

Paraneoplastic Syndromes Related to Lung Cancer

Cited by 17 publications

References 22 publications

Hyperpigmentation in palms associated with lung adenocarcinoma resolving after chemotherapy

Hyperpigmentation in palms associated with lung adenocarcinoma resolving after chemotherapy

Paraneoplastic Syndromes in Lung Cancer

A case of acanthosis nigricans as a paraneoplastic syndrome with squamous cell lung cancer

Contact Info

Product

Resources

About