Osteosarcoma of the jaw

Abstract

We found that tumor size and surgical margins were significant prognostic factors. Early diagnosis of these tumors is mandatory to improve survival; the role of Ct and Rt is still unknown.

Clinical, therapeutic and prognostic features of osteosarcoma of the jaws – Experience of 36 cases

“…This is in accordance with some (Caron et al, 1971;Garrington et al, 1967) but not most of prior studies in which the occurrence of chondroplastic subtype was found most commonly (Clark et al, 1983;Delgado et al, 1994;Freyschmidt and Ostertag, 1988;Goepfert et al, 1990;Salvati et al, 1993;Vege et al, 1991). Huvos et al found the fibroblastic to be most common (Huvos,1991).…”

“…The present study had only two cases of metastasis in the lung (5%). In earlier studies it was assumed that osteosarcoma in the jaws have a lesser grade of differentiation than osteosarcoma of the long bones (Roca et al, 1970;Russ and Jesse, 1980) whereas recent studies report high-grade tumours in 87e90% of osteosarcoma of the jaws (Bertoni et al, 1991;Delgado et al, 1994). However, OSJ shows significantly less metastasis than osteosarcoma of the long bones (Clark et al, 1983;Delgado et al, 1994;Mark et al, 1991) with a preference to local relapse (Batsakis, 1984).…”

Gnathic Osteosarcoma: A Retrospective Analysis over a 20 Year Period

“…10 OS of long bones affects mainly adolescents and young adults, where as gnathic OS seen mainly in middle age (third to fourth decade of life). [11][12][13][14][15][16] However, the peculiarity in our sample was that OS is mostly seen in young adults (second decade). Similar age group was afftected in an Iranian study.…”

“…17,18 OS of jaws rarely metastasizes to other parts of the body as seen in the present patients where there was no metastasis. [11][12][13] With respect to treatment, controversy still exists regarding the combination of surgery, radiotherapy and chemotherapy. [19][20][21] However, in all 13 cases of OS, here were treated with a combination of surgery and radiotherapy.…”

Primary osteosarcoma of the head and neck in pediatric patients

“…Osteosarcomas of the head and neck represent a small percentage of osteosarcomas with studies reporting occurrences between 0.5-8.1% 1,[5][6][7][8][9][10][11][12] and an average between 6 -7%. Head and neck osteosarcomas are infrequent and usually present in the third to fourth decades of life, almost a decade after the most common presentation of long-bone tumors.…”