Gnathic Osteosarcoma: A Retrospective Analysis over a 20 Year Period

Abstract

BackgroundOsteosarcomas are very rare malignant mesenchymal neoplasms affecting jaw bones. Only few studies are reported about this lesion in this particular region. ObjectiveWe wanted to assess the demography and tumor behaviour and histopathological pattern, retrospectively in the available cases. MethodsA retrospective analysis of hospital records for 20 years was carried out. Clinical features, radiographic findings, histopathological details and treatment aspect of each of the lesions was considered.

Osteosarcoma -An Osteolytic Lesion inthe Posterior Mandible –A Case Report With Review of Literature

“…Lesion recurred extensivelyandsubsequently became completely radiolucent suggesting mesenchymal malignancy or fibrous dysplasia turning into fibroblastic variant of osteosarcoma. 10,19 The differential diagnosis of fibroblastic osteosarcoma should include, Ewing's sarcoma, bone metastasis, fibrous dysplasia in early stage , osteomyelitis, and even lesions that do not usually affect the jaw bones, such as fibrosarcoma, leiomyosarcomas, or rhabdomyosarcomas. 33 Misdiagnosed cases of osteosarcoma frequently reported in various literatures.Rosilene et al, reported a case of osteosarcoma of mandible initially resembling of periapical lesion and after initial endodontic treatment, a significant increase in the size of the lesion occurred 34 PriyankaDebta 35et al also misdiagnosed a case of osteosarcoma as benign cystic lesion which recurred aggressively to cause extensive destruction.…”

Collision Tumor of Maxilla: A Diagnostic Dilemma

“…A tissue biopsy is the only way of establishing a diagnosis, yet an incisional biopsy may lead to a wrong diagnosis as in our case and there is greater need for immunohistochemistry in these cases. In general, osteoblastic tumors are most common but the chondroblastic variant still persists in case of jaw tumors [4]. In spite of all investigations, a differential such as chondrosarcoma, Ewing's Sarcoma, Osteiod Osteoma, Odontogenic Myxoma may be considered.…”

“…Radiographically, the lesion shows a bizarre form of radiolucency and radio opacity occurring together, this hallmark is rarely found in initial cases. However widening of periodontal ligament space is pathognomonic [4]. Computed tomography and MRI are the mainstay for the diagnosis of OS and its relation to its surrounding structures.…”