Ossifying Sarcoma of the Skin Metastatic From Ossifying Sarcoma of the Humerus

Osteosarcoma of the skin

“…Two patients, excluding the Mayo Clinic Rochester patient whose case is described in our case report, had cutaneous metastases already present at diagnosis of osteosarcoma 9,10 . In four patients, including the patient in our case report, skin involvement was the first sign of metastases 2,6,10 . In our case and that of Stavrakakis et al.…”

“…Skeletal osteosarcoma is typically diagnosed in the second decade of life. However, in three patients in our review, it was diagnosed much later, at ages 43 years, 2 54 years, 6 and 75 years 8 . The scalp was the most common location of cutaneous metastases (nine of the 13 cases).…”

“…Cutaneous metastases of primary osteosarcoma were reported as early as 1924 by Finnerud 2 . However, most case reports of cutaneous metastases of primary osteosarcoma have been published in the past 10 years.…”

Primary cutaneous extraskeletal osteosarcoma under a previous electrodessicated actinic keratosis

“…[14][15][16][17][18][19][20][21] In our case the possibility of skeletal origin was excluded by the CT scan findings and observations at surgery. When making a differential diagnosis, bone forming soft-tissue tumors such as myositis ossificans and sarcomas with osseous metaplasia including fibrosarcoma, malignant fibrous histiocytoma, synovial sarcoma, epithelioid sarcoma, and liposarcoma should be excluded.…”

Osteosarcoma with Cutaneous Metastases

“…7,8 The first description of osteosarcoma with cutaneous metastasis came from Finnerud et al, in 1924; a case of osteosarcoma of the right humerus with metastases to scalp and left submaxillary region was reported. 9 In 1927 Jeffree et al reported 2 cases of osteosarcoma with subcutaneous and 1 case with a scalp metastasis in a review of 152 cases of metastatic osteosarcoma. 10 Myhand et al, in 1995, documented a case of osteosarcoma of the clavicle with a cutaneous …”