Osmolality and pH of commercially available contact lens care solutions and eye drops

Pena-Verdeal, Hugo; Garcia-Queiruga, Jacobo; García-Resúa, Carlos; Yebra‐Pimentel, Eva; Giráldez, María Jesús

doi:10.1016/j.clae.2020.10.009

Cited by 13 publications

(18 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the other hand, the reduction in comfort could be associated with the viscosity sensation of the 0.3% hyaluronic acid on the ocular surface but also, as an alternative hypothesis, with the fact that these eye drops were hypo-osmotic. 28 Nevertheless, the 0.2% hyaluronic acid presented the same hypo-osmolarity but did not affect comfort, which would not support the previous hypothesis. Another important consideration was that participants were neophytes and did not present symptomatology of contact lens discomfort.…”

Section: Discussionmentioning

confidence: 64%

Improvement of Soft Contact Lens Wettability After the Instillation of Hyaluronic Acid Eye Drops

Pastrana

Carpena-Torres

Rodríguez-Pomar

et al. 2022

Eye &Amp; Contact Lens: Science &Amp; Clinical Practice

View full text Add to dashboard Cite

To evaluate the effect of the topical instillation of hyaluronic acid eye drops with different viscosity on soft contact lens wettability and comfort. Methods: A randomized and participant-masked study was performed, involving 20 participants (25.462.6 years). One eye wore hydrogel (ocufilcon D) contact lenses, and another eye wore silicone-hydrogel (somofilcon A) contact lenses. The in vivo wettability tear film surface quality (TFSQ) index and comfort were measured before and after the instillation of different eye drops: saline solution (control) and 0.1%, 0.2%, and 0.3% hyaluronic acid. Results: Compared with saline solution, the instillation of 0.1%, 0.2%, and 0.3% hyaluronic acid improved the in vivo wettability of the hydrogel contact lenses by decreasing their TFSQ mean for 5, 10, and 30 min, respectively (P,0.05). During silicone-hydrogel contact lens wear, the hyaluronic acid did not affect wettability because there were no changes in TFSQ mean (P$0.05), but the 0.3% hyaluronic acid produced a decrease in comfort for the first 3 min (P,0.05). Conclusions: The instillation of hyaluronic acid eye drops increased the in vivo wettability of the hydrogel contact lens, and the duration of this effect was directly related to its concentration and viscosity.

show abstract

Section: Discussionmentioning

confidence: 64%

Improvement of Soft Contact Lens Wettability After the Instillation of Hyaluronic Acid Eye Drops

Pastrana

Carpena-Torres

Rodríguez-Pomar

et al. 2022

Eye &Amp; Contact Lens: Science &Amp; Clinical Practice

View full text Add to dashboard Cite

show abstract

“…In a physiological environment, MA became fully ionized reaching the maximum EWC of etafilcon A. At higher pH, higher than the physiological environment, around 7.0 or 7.4, the EWC of etafilcon A contact lens became constant due to the fully ionized MA [ 14 , 20 ]. However, under the physical pH, the MA is hardly fully ionized resulting in the reduced EWC where they showed significantly reduced EWC.…”

Section: Discussionmentioning

confidence: 99%

“…For example, the normal physiological pH is 7.4, while the pH of the tear film ranges from 5.9 to 7.9, which is affected by various factors such as diseases, contact lens wear, and air pollution [ 10 , 11 , 12 , 13 ]. The pH of contact lens care solutions or eye drops vary from 6.69 to 7.98 and from 6.36 to 7.99 respectively where the contact lenses are immersed in [ 14 ]. The fluctuation of the pH of swelling media could affect the physical properties of contact lenses, especially ionic contact lenses and the state of water.…”

Section: Introductionmentioning

confidence: 99%

The pH-induced physical properties of ionic contact lens material

Ahn¹,

Choi²

2023

Heliyon

View full text Add to dashboard Cite

“…41 One strength of the present study was the use of daily contact lenses, which avoids the use of such the physical properties of those products that could affect the tear film characteristics. 42 Nevertheless, even though daily disposable contact lenses avoid ocular surface chronic exposure to lens care solutions, 5,7 contact lens wearers are still exposed to lens packaging solutions. 43 It should be noted in contrast with other analyses, 9 the present study utilized a randomized double-blind design to have no affected on the results.…”

Section: Discussionmentioning

confidence: 99%

Changes of symptomatology, tear film and ocular surface integrity one week during Somofilcon-A and Omafilcon-A lens wear

Pena-Verdeal

Noya-Padin

Losada-Oubiña

et al. 2022

European Journal of Ophthalmology

Self Cite

View full text Add to dashboard Cite

Purpose Clinicians play a key role in prescribing contact lenses that best suited for fitting which materials had an impact on ocular surface parameters. The present study aimed to evaluate the impact on symptomatology, tear film dynamics and ocular surface integrity of a silicone-hydrogel (Somofilcon-A) and a hydrogel (Omafilcon-A) lens before and after wearing for one week in contact lens neophyte participants. Methods A Somofilcon-A and Omafilcon-A were randomly fitted to one or other the eye on an initial group of 28 participants. Subjects were scheduled for three sessions: basal session previous fitting, second session after 4-wear hours, and final session after 7-wear days for up to 10 h. In each session, CLDEQ-8, tear meniscus height and hyperemia with and without lenses, as well as lipid layer thickness and corneal/conjunctival staining without lenses were assessed. Values were compared between lenses and sessions. Results In intrasession comparison, there were no differences in any parameter between materials on any session with or without lenses (all p≥0.176), except on the conjunctival staining where values obtained during Somofilcon-A wear (all p ≤ 0.006). In intersession analysis, CLDEQ-8 score, tear meniscus height and lipid layer thickness showed a statistical difference during both materials wear (all p ≤ 0.009), while conjunctival hyperemia does not (p = 0.237); corneal staining showed differences during Omafilcon-A wear (p = 0.037), contrary to conjunctival staining which showed differences only during Somofilcon-A wear (p < 0.001). Conclusion Contact lenses wear had an impact on ocular parameters that have some specific influences of the material on which lenses were manufactured.

show abstract

Osmolality and pH of commercially available contact lens care solutions and eye drops

Cited by 13 publications

References 58 publications

Improvement of Soft Contact Lens Wettability After the Instillation of Hyaluronic Acid Eye Drops

Improvement of Soft Contact Lens Wettability After the Instillation of Hyaluronic Acid Eye Drops

The pH-induced physical properties of ionic contact lens material

Changes of symptomatology, tear film and ocular surface integrity one week during Somofilcon-A and Omafilcon-A lens wear

Contact Info

Product

Resources

About