2020
DOI: 10.1016/j.clae.2020.10.009
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Osmolality and pH of commercially available contact lens care solutions and eye drops

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Cited by 11 publications
(5 citation statements)
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“…On the other hand, the reduction in comfort could be associated with the viscosity sensation of the 0.3% hyaluronic acid on the ocular surface but also, as an alternative hypothesis, with the fact that these eye drops were hypo-osmotic. 28 Nevertheless, the 0.2% hyaluronic acid presented the same hypo-osmolarity but did not affect comfort, which would not support the previous hypothesis. Another important consideration was that participants were neophytes and did not present symptomatology of contact lens discomfort.…”
Section: Discussionmentioning
confidence: 64%
“…On the other hand, the reduction in comfort could be associated with the viscosity sensation of the 0.3% hyaluronic acid on the ocular surface but also, as an alternative hypothesis, with the fact that these eye drops were hypo-osmotic. 28 Nevertheless, the 0.2% hyaluronic acid presented the same hypo-osmolarity but did not affect comfort, which would not support the previous hypothesis. Another important consideration was that participants were neophytes and did not present symptomatology of contact lens discomfort.…”
Section: Discussionmentioning
confidence: 64%
“…In a physiological environment, MA became fully ionized reaching the maximum EWC of etafilcon A. At higher pH, higher than the physiological environment, around 7.0 or 7.4, the EWC of etafilcon A contact lens became constant due to the fully ionized MA [ 14 , 20 ]. However, under the physical pH, the MA is hardly fully ionized resulting in the reduced EWC where they showed significantly reduced EWC.…”
Section: Discussionmentioning
confidence: 99%
“…For example, the normal physiological pH is 7.4, while the pH of the tear film ranges from 5.9 to 7.9, which is affected by various factors such as diseases, contact lens wear, and air pollution [ 10 , 11 , 12 , 13 ]. The pH of contact lens care solutions or eye drops vary from 6.69 to 7.98 and from 6.36 to 7.99 respectively where the contact lenses are immersed in [ 14 ]. The fluctuation of the pH of swelling media could affect the physical properties of contact lenses, especially ionic contact lenses and the state of water.…”
Section: Introductionmentioning
confidence: 99%
“…41 One strength of the present study was the use of daily contact lenses, which avoids the use of such the physical properties of those products that could affect the tear film characteristics. 42 Nevertheless, even though daily disposable contact lenses avoid ocular surface chronic exposure to lens care solutions, 5,7 contact lens wearers are still exposed to lens packaging solutions. 43 It should be noted in contrast with other analyses, 9 the present study utilized a randomized double-blind design to have no affected on the results.…”
Section: Discussionmentioning
confidence: 99%