Oral health, diabetes, and body weight

Cintra, Luciano Tavares Ângelo; Samuel, Renata Oliveira; Prieto, Annelise Katrine Carrara; Sumida, Dóris Hissako; Dezan, Elói; Gomes‐Filho, João Eduardo

doi:10.1016/j.archoralbio.2016.10.002

Cited by 19 publications

(21 citation statements)

References 27 publications

(60 reference statements)

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“…In the current study, the mean body weight at the end of the experimental period in all diabetic groups was reduced and weight losses were maintained throughout the experimental period. These findings are in agreement with related studies [20,21] concluding that diabetic group had lower body weight than control group due to lack or reduced anabolic insulin hormone [22] followed by loss of tissue proteins during release of amino acids for gluconeogenesis [23] thus initiating progressive loss of body weight.…”

Section: Discussionsupporting

confidence: 93%

A Histomorphometric Study on the Neurohypophysis of STZinduced Diabetic Albino Rats

Faizal

Khan

2018

International Journal of Neurology Research

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sectioning. Routine and special stained sections were studied under the light microscope and relevant findings were recorded. RESULTS: Data obtained from biochemical analyses and histomorphometry along with the histopathological features revealed that with increasing duration of hyperglycemia was associated with increased serum creatinine and reduction in serum total protein; increased mean percentage of darkly stained large sized pituicytes and notable thickening of perisinusoidal collagen. CONCLUSION: It is therefore concluded that long-standing hyperglycemia which is associated with increased occurrence of predominantly large and darkly stained pituicytes and remarkably increased deposition of perisinusoidal collagen appear to be the important contributing factors somehow responsible for the derangement of the function of the posterior pituitary in chronic diabetes.

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Section: Discussionsupporting

confidence: 93%

A Histomorphometric Study on the Neurohypophysis of STZinduced Diabetic Albino Rats

Faizal

Khan

2018

International Journal of Neurology Research

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“…This difference in body weight is caused by the absence of insulin metabolism leading to a catabolic state that causes severe depletion of energy stores and proteins, particularly those found in the skeletal muscle (21). The changes in body weight were observed in another study and even changes in organs such as the liver, brain, heart, and gonads (22).…”

Section: Discussionmentioning

confidence: 95%

Influence of Apical Periodontitis on Stress Oxidative Parameters in Diabetic Rats

Prieto

Gomes‐Filho

Azuma

et al. 2017

Journal of Endodontics

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“…42 In addition, the studies showed that the associations among AP, PD, and diabetes increased the weights of the brain, heart, and gonads and the total body weight of rats. 43 According to the authors, these results demonstrate that AP can affect the body system. 43 Another study using an animal model showed how AP can affect the oxidative stress parameters in the presence of diabetes.…”

Section: Continuationmentioning

confidence: 92%

“…43 According to the authors, these results demonstrate that AP can affect the body system. 43 Another study using an animal model showed how AP can affect the oxidative stress parameters in the presence of diabetes. 6 The findings showed that AP might potentiate diabetes pathogenesis, increasing the levels of uric acid, which serve as a marker for chronic kidney disease.…”

Section: Continuationmentioning

confidence: 92%

Endodontic medicine: interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materials

et al. 2018

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Endodontic medicine, which addresses the bidirectional relationship between endodontic infections and systemic diseases, has gained prominence in the field of endodontics. There is much evidence showing that while systemic disease may influence the pathogenesis of endodontic infection, endodontic infection can also cause systemic alterations. These alterations include more severe bone resorption and inflammation in the periapical area as well as enhanced systemic disease symptoms. Similarly, many reports have described the impact of systemic diseases on the tissue responses to dental materials. Conversely, the local use of dental materials may show systemic effects in the form of altered production of biomarkers. Thus, studies to better understand the mechanisms related to those connections are extremely important. In this context, the objective of this review was to analyze and discuss the current literature regarding the connections among these three factors-systemic diseases, endodontic infection, and endodontic dental materials-and determine how these connections may interfere in the systemic health status and the endodontic treatment outcomes, which are represented by periapical wound healing.

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Oral health, diabetes, and body weight

Abstract: Apical periodontitis and periodontal disease may potentiate the adverse effects of diabetes.

Cited by 19 publications

References 27 publications

A Histomorphometric Study on the Neurohypophysis of STZinduced Diabetic Albino Rats

A Histomorphometric Study on the Neurohypophysis of STZinduced Diabetic Albino Rats

Influence of Apical Periodontitis on Stress Oxidative Parameters in Diabetic Rats

Endodontic medicine: interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materials

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