Optical Measurement of Straylight in Eyes With Cataract

Şahin, Onurcan; Pennos, Alexandros; Ginis, Harilaos; Hervella, Lucía; Villegas, Eloy A.; Cañizares, B. Povedano; Marı́n, José Marı́a; Pallikaris, Ioannis G.; Artal, Pablo

doi:10.3928/1081597x-20160920-02

Cited by 12 publications

(11 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…1,9 In a normal, nonpathological population, intraocular scattering is influenced by both genetic and environmental factors. 10 Aging as well as various pathological conditions, such as cataracts [11][12][13][14][15] and dry eye disease [16][17][18][19] (DED), can affect ocular media and thus increase intraocular scattering. In addition, as the tear film breaks as part of the normal blinking pattern, light scatter increases which in turn decreases contrast sensitivity temporarily until a new blink reconstructs the tear film.…”

Section: Introductionmentioning

confidence: 99%

Intraocular Scattering, Blinking Rate, and Tear Film Osmolarity After Exposure to Environmental Stress

Tabernero

García-Porta

Artal

et al. 2021

Trans. Vis. Sci. Tech.

Self Cite

View full text Add to dashboard Cite

Dry environments, such as those in offices or aircraft cabins, can potentially generate ocular discomfort and alter the tear film. We compare light scatter, blinking rate, and tear osmolarity in young and older subjects after exposure to low humidity using a controlled environmental chamber.Methods: Two groups of healthy subjects were recruited; younger (N = 13, 27 ± 6 years) and older (N = 23, 71 ± 7 years). Measurements were carried out before and after 90minute exposure to low relative humidity (5%) and constant temperature (23 degrees). Ocular light scatter was measured using a double-pass instrument (OQAS, Visiometrics, Spain). Blinking rate was monitored using an infrared video camera. Tear osmolarity was measured using the TearLab system (Escondido, CA, USA).Results: Ocular light scatter increased by a factor of 10% after exposure to low humidity in the older group (P = 0.03) but did not change significantly in the younger group. Blinking rate increased significantly (40% more blinks) in both groups but there was no difference between the groups. No significant differences in osmolarity were shown between two age groups or as result of environmental stress. Conclusions:Exposure to dry environment increased light scatter in older subjects. Although more blinks were triggered in both younger and older groups to prevent corneal dehydration, there was no difference between the groups. Blink rate and osmolarity are not associated with the difference in light scatter.Translational Relevance: Our work approaches a clinical care problem using basic research methods (measuring ocular scatter and blink ratio).

show abstract

Section: Introductionmentioning

confidence: 99%

Intraocular Scattering, Blinking Rate, and Tear Film Osmolarity After Exposure to Environmental Stress

Tabernero

García-Porta

Artal

et al. 2021

Trans. Vis. Sci. Tech.

Self Cite

View full text Add to dashboard Cite

show abstract

“…Straylight (forward scatter) component is determined objectively by implementation of a single parameter such as log(s) or the objective scatter index, which represents general behavior of the light beam propagating in the ocular media and does not provide any spatially resolved information [16][17][18]. The concept of straylight measurement is used in the commercial systems like C-Quant (Oculus GmbH, Germany) or Optical Quality Analysis System -High Definition Analyzer (Visiometrics SL, Spain) that have been introduced to clinical practice to assess intraocular scattering [17,[19][20][21]. The analysis of Purkinje images enables also determination of the corneal and lenticular contribution to intraocular scattering without any impact of the retina (as in the double-pass systems) [22].…”

Section: Introductionmentioning

confidence: 99%

Volumetric macro- and micro-scale assessment of crystalline lens opacities in cataract patients using long-depth-range swept source optical coherence tomography

Grulkowski

Manzanera

Cwiklinski

et al. 2018

Biomed. Opt. Express

Self Cite

View full text Add to dashboard Cite

We demonstrate an optimized optical platform for the three-dimensional (3-D) visualization of crystalline lens opacities in vivo in the eyes of patients with different types and grades of cataracts. We developed a prototype long-depth-range swept source optical coherence tomography (SS-OCT) instrument operating at the speed of 50 kA-scans/second and at the central wavelength of 1 μm to perform high-resolution imaging of the whole anterior segment of the eye. Volumetric data sets of cataractous eyes were acquired and processed to obtain contrast-enhanced high-resolution images of lenticular structures and opacifications. The results showed lens micro-and macro-scale features related to possible cataract development such as cortical spokes, water clefts and enhanced scattering in the lens nucleus. The results demonstrate also the ability of this SS-OCT imaging to locate and characterize opacities quantitatively. The instrument might be a useful tool in the highresolution preoperative evaluation of crystalline lens opacities in cataract patients.

show abstract

“…Some alternatives in the second group measure the degradation of the retinal image quality produced by scatter. This can be achieved by recording double-pass retinal images (60) and quantifying the impact of the cataracts (61,62).…”

Section: Imaging the Crystalline Lens And Its Opacitiesmentioning

confidence: 99%

Simulating Outcomes of Cataract Surgery: Important Advances in Ophthalmology

Marcos

Martinez-Enriquez

Viñas

et al. 2021

Annu. Rev. Biomed. Eng.

Self Cite

View full text Add to dashboard Cite

As the human eye ages, the crystalline lens stiffens (presbyopia) and opacifies (cataract), requiring its replacement with an artificial lens [intraocular lens (IOL)]. Cataract surgery is the most frequently performed surgical procedure in the world. The increase in IOL designs has not been paralleled in practice by a sophistication in IOL selection methods, which rely on limited anatomical measurements of the eye and the surgeon's interpretation of the patient's needs and expectations. We propose that the future of IOL selection will be guided by 3D quantitative imaging of the crystalline lens to map lens opacities, anticipate IOL position, and develop fully customized eye models for ray-tracing-based IOL selection. Conversely, visual simulators (in which IOL designs are programmed in active elements) allow patients to experience prospective vision before surgery and to make more informed decisions about which IOL to choose. Quantitative imaging and optical and visual simulations of postsurgery outcomes will allow optimal treatments to be selected for a patient undergoing modern cataract surgery. Expected final online publication date for the Annual Review of Biomedical Engineering, Volume 23 is June 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

show abstract

Optical Measurement of Straylight in Eyes With Cataract

Cited by 12 publications

References 12 publications

Intraocular Scattering, Blinking Rate, and Tear Film Osmolarity After Exposure to Environmental Stress

Intraocular Scattering, Blinking Rate, and Tear Film Osmolarity After Exposure to Environmental Stress

Volumetric macro- and micro-scale assessment of crystalline lens opacities in cataract patients using long-depth-range swept source optical coherence tomography

Simulating Outcomes of Cataract Surgery: Important Advances in Ophthalmology

Contact Info

Product

Resources

About