Open Clinical Trial for Evaluation of Efficacy and Safety of a Portable “Dry-Type” Iontophoretic Device in Treatment of Palmar Hyperhidrosis

“…Of two small nonrandomized comparisons of a handheld ‘dry type’ iontophoresis device compared with no treatment, only one found a statistically significant reduction in sweating, assessed by gravimetry …”

Section: Resultsmentioning

confidence: 99%

Interventional management of hyperhidrosis in secondary care: a systematic review

et al. 2018

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“…Beyond promising efficacy results, this approach can be performed without limiting daily activities. 10,33 Botulinum Toxin Injectable BoNT has established its role in the nonsurgical management of PH, being widely used as a firstor second-line therapy, depending on disease severity. 2,5,8 By targeting the SNARE protein complex, BoNTs reversibly block the release of acetylcholine from presynaptic nerve terminals, preventing sweat secretion by "chemical denervation".…”

Section: Iontophoresismentioning

confidence: 99%

<p>Management Strategies Of Palmar Hyperhidrosis: Challenges And Solutions</p>

Gregoriou

Sidiropoulou

Kontochristopoulos

et al. 2019

CCID

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Palmar hyperhidrosis is a potentially disabling condition for which management remains a therapeutic challenge. Given the significant impact on quality of life, various treatment options are available, ranging from topical agents and medical devices to systemic therapies and surgical interventions. Nonsurgical approaches, i.e. topical antiperspirants, botulinum toxin injections, iontophoresis, and systemic agents, are all supported by the current literature. Patients with mild-to-moderate disease can often benefit from topical therapies only. As disease severity progresses, systemic oral medication, such as anticholinergic drugs, usually becomes necessary. Last-line surgical approaches (sympathetic denervation) should be reserved for severe refractory cases. Recently, therapeutic strategies have been evolving with several new agents emerging as promising alternatives in clinical trials. In practice, however, each modality comes with its own benefits and risks. An individual therapeutic ladder is generally recommended, taking into account disease severity, benefit-to-risk profile, treatment cost, patient preference, and clinician expertise. This review will provide an update on current and emerging concepts of management for excessive hand sweating to help clinicians optimize therapeutic decision-making.

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“…Patients who are pregnant, have metal implants, pacemakers or have epilepsy cannot take the treatment 18 . Transient vesiculation, redness, paresthesia, and discomfort are the side effects 57,58 …”

Section: Device‐based Treatmentsmentioning

confidence: 99%

Treatment of Axillary hyperhidrosis

Arora¹,

Kassir

Patil

et al. 2021

J of Cosmetic Dermatology

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Background Axillary hyperhidrosis characterized by excessive sweating in the axillary regions is a frustrating chronic autonomic disorder leading to social embarrassment, impaired quality of life and usually associated with palmoplantar hyperhidrosis. Identifying the condition and its cause is central to the management. Aim The aim of this article is to discuss treatment options for axillary hyperhidrosis. Methods Comprehensive literature search using PubMed and Google Scholar was performed to review relevant published articles related to diagnosis and treatment of axillary hyperhidrosis. Results Treatment modalities for axillary hyperhydrosis vary from topical and systemic agents to injectables, newer devices and surgical measures. None except for physical measures using devices or surgery, which destroys the sweat glands to remove them, is possibly permanent and most are associated with attendant side effects. Conclusion Several treatments including medical and surgical option are available for the treatment of axillary hyperhydrosis. Patient education is important component of its management. Individualized approach of management is necessary for optimal outcome of treatment.

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Open Clinical Trial for Evaluation of Efficacy and Safety of a Portable “Dry-Type” Iontophoretic Device in Treatment of Palmar Hyperhidrosis

Abstract: The device is an effective therapeutic modality for palmar hyperhidrosis in addition to local injection of botulinum toxin, endoscopic sympathectomy, and conventional iontophoretic treatments.

Cited by 12 publications

References 7 publications

Interventional management of hyperhidrosis in secondary care: a systematic review

Interventional management of hyperhidrosis in secondary care: a systematic review

<p>Management Strategies Of Palmar Hyperhidrosis: Challenges And Solutions</p>

Treatment of Axillary hyperhidrosis

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