Treatment of Axillary hyperhidrosis

Abstract

Background Axillary hyperhidrosis characterized by excessive sweating in the axillary regions is a frustrating chronic autonomic disorder leading to social embarrassment, impaired quality of life and usually associated with palmoplantar hyperhidrosis. Identifying the condition and its cause is central to the management. Aim The aim of this article is to discuss treatment options for axillary hyperhidrosis. Methods Comprehensive literature search using PubMed and Google Scholar was performed to review relevant published articles related to diagnosis and treatment of axillary hyperhidrosis. Results Treatment modalities for axillary hyperhydrosis vary from topical and systemic agents to injectables, newer devices and surgical measures. None except for physical measures using devices or surgery, which destroys the sweat glands to remove them, is possibly permanent and most are associated with attendant side effects. Conclusion Several treatments including medical and surgical option are available for the treatment of axillary hyperhydrosis. Patient education is important component of its management. Individualized approach of management is necessary for optimal outcome of treatment.

Aluminum‐containing antiperspirants are not associated with breast cancer

“…1,2 Topical antiperspirants containing aluminum chloride are often used for patients with axillary hyperhidrosis and in the general population for personal hygiene. 3 Aluminum is known to have a genotoxic profile, capable of causing both DNA alterations and epigenetic changes. Furthermore, aluminum in the form of aluminum chloride or aluminum chlorohydrate may mimic estrogen, thus also having the potential to contribute to breast cancer progression.…”

Axillary hyperhidrosis: An update

“…Therapy revolves around general measures to reduce sweating (wearing loose fitting cotton clothing and avoiding friction), topical and systemic agents, and surgeries [Table 3] in refractory cases. [10,11] Topical Aluminum salts (12.5-30%) constitute the first line of treatment. There is occlusion of the distal ducts, and prolonged blockage of the glands leads to acinar degeneration and reduced sweat.…”

Comparison of 10 versus 20 sessions tap water iontophoresis efficacy in the treatment of palmoplantar hyperhidrosis

“…Primary hyperhidrosis (HH) is a chronic disorder of excessive sweating that most commonly occurs in the palmoplantar areas and axillae 1–5 . Since it disrupts professional life and leads to social embarrassment, providing effective treatment is crucial.…”

“…

Primary hyperhidrosis (HH) is a chronic disorder of excessive sweating that most commonly occurs in the palmoplantar areas and axillae. [1][2][3][4][5] Since it disrupts professional life and leads to social embarrassment, providing effective treatment is crucial. Topical aluminum salts are recommended as the first-line therapy because of their safety, affordability, and ease of application, while they have limited clinical efficacy.

…”