Op059

Чиссов, В. И.; Reshetov, I.; Boiko, A. V.; Черниченко, А В; Edemskaya, Olga V.; Polyakov, A.

doi:10.1016/j.oraloncology.2013.03.067

Cited by 3 publications

(4 citation statements)

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“…This clinical case makes it original that there is a fact of metastatic lesion of the inguinal nodes. Since the literature describes cases of lesions of the supraclavicular nodes on the left -Virchow nodes, bilateral ovarian lesions -Krukenberg's tumors, metastases in the paraumbilical region -Sister Mary Joseph's nodules, the Irish node -metastasis in the left axillary region, Schnitzler metastasis -in the lymph nodes of the pararectal tissue, a large tumor node in the pelvis, determined by rectal and vaginal examination (Blumer's protrusion) (6). The purpose of the article is to draw the attention of clinician-oncologists and other doctors to the possible metastasis of gastric cancer into completely unexpected groups of lymph nodes and organs that do not fall within the generally accepted classification and, possibly, by publication to attract attention and find other similar cases in order to satisfy the pattern of the indicated metastasis and use these data for tertiary prophylaxis (prevention, early diagnosis and treatment of relapses) (7).…”

Section: Discussionmentioning

confidence: 99%

Clinical case of complications of inguinal node metastatic lesion in gastric cancer after surgical treatment

Shtefanov

Zhakipova²,

Mukhtarova

et al. 2019

Electron J Gen Med

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Objective: To study the phenomena of complications of atypical distant lymphangitic metastasis by the example of gastric cancer. Methods: Within the framework of the study "Hereditary diffuse gastric cancer and measures for its prevention", a clinical group and a control group of patients with the most likely risk of developing this genetic disease were recruited. DNA samples were taken from 119 patients of the main clinical group and the control group. In the course of filling out statistical charts, questioning and examination of patients, cases of distant lymphangitic and hematogenous metastasis were revealed in 7 patients. As diagnostic methods for distant lymphangitic and hematogenous metastasis, we used the results of studies of computed tomography, positron emission tomography combined with computed tomography of the whole body, nuclear magnetic resonance imaging, ultrasound methods, open biopsy and trephine-biopsy of lymph nodes. Results: Krukenberg's tumors were detected in 2 patients, Virchow's metastases-in 2 patients, metastases in the paraumbilical region-in 2 patients, Schnitzler metastases-in 1 patient, Irish node was detected in 1 of the examined patients. There was also a metastatic lesion of the lymph nodes of inguinal region on the left in 2 patients and one case of metastasis to the right testicle in a patient with true inguinal cryptorchidism. This article reflects one case of metastatic lesion of the inguinal nodes on the left and subsequent complications in the form of lymphostasis and pain syndrome. Conclusion: According to the classification of distant metastases in case of malignant neoplasms of the stomach, classical cases of metastases of Krukenberg, Virchow, Schnitzler, Sister Mary Joseph, and Irish were revealed. There is atypical metastasis to the inguinal nodes and to the undescended (true inguinal cryptorchidism) right testicle, which does not fall under the generally accepted classification of distant metastases of gastric cancer. Further tactics of treatment in the case of metastatic lesion to the inguinal regions in gastric cancer are not entirely clear, which requires an increase in the study of the amount of these clinical cases.

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Section: Discussionmentioning

confidence: 99%

Clinical case of complications of inguinal node metastatic lesion in gastric cancer after surgical treatment

Shtefanov

Zhakipova²,

Mukhtarova

et al. 2019

Electron J Gen Med

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“…Дані літератури стверджують, що найкращий прогноз стосовно загальної і безрецидивної виживаності очікується у випадках, коли «базовий» рівень СА-125 після завершення комплексного лікування не перевищує 10 Од/мл [4,10,11]. При цьому зменшення рівня маркерів від цієї величини на кожну 1 Од/мл веде до збільшення часу стабілізації на кілька місяців [5,10,12].…”

Section: Introductionunclassified

“…The literature suggests that the best prognosis for promotion to overall and relapse-free survival is expected in cases where the "baseline" level of CA-125 after completion of complex treatment does not exceed 10 U/ml [10,11,4]. The decrease in the level of markers from this value for every 1 U/ml leads to an increase in stabilization time for several months [5,10,12].…”

Section: Introductionmentioning

confidence: 99%

Risk of recurrence of malignant tumors of the ovaries and levels of tumor markers НЕ-4 and СА-125

2020

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Background. Timely diagnosis of recurrence of malignant tumors of the ovaries can improve treatment outcomes. Purpose – determine the feasibility of using the tumor marker HE-4 in case of recurrence of malignant ovarian tumors. Materials and methods. To analyze the levels of HE-4 and CA-125 in patients with recurrence of malignant ovarian tumors and determine the feasibility of using HE-4 at this stage of monitoring, 29 patients with known indicators of HE-4 and CA-125 at the time of recurrence and their baseline data were selected. Results and discussion. The paper presents the results of the study of the HE-4 and CA-125 tumor markers levels in 29 patients with a proven recurrence of malignant ovarian neoplasms depending on the timing of its appearance – up to 12 months (n = 9), 13–24 months (n = 11) and after 24 months (n = 9). The values of the tumor-associated HE-4 marker were decreased during the relapse compared to baseline expression levels. When analyzing of the HE-4 serum, their significant difference was revealed only in the event of relapse in the period of up to one year (1207.00 pmol/l) from recurrence rates in the periods of 13–24 and of over 24 months (567.00 and 655.50 pmol/l, respectively). Conclusions. Only the baseline expression of HE-4 is prognostically significant for determining the timing of recurrence of ovarian malignancies.

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“…At the same time, Chissov V.I., Daryalova S.L. [8] believe that chemotherapy and radiation methods rarely regress a tumour, and the life expectancy after it does not exceed 13 months.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer

Orazbayev¹,

Мусулманбеков²,

Bukenov³

2019

Open Access Maced J Med Sci

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AIM:This study aims to evaluate the methods of treatment of the thoracic part of oesophagal cancer and to predict the results of treatment depending on the factors of the prognosis.MATERIALS AND METHODS:The results of treatment of 366 patients with cancer of the thoracic part of the oesophagus for 10 years (2007-2016) by the department of thoracic oncology of the Karaganda oncological dispensary were studied.RESULTS:The overall five-year survival rate, regardless of the method of treatment, was only 8.72% (28 of 321), and in the 6-10 year period 8.41% (27 of 321) lived, p < 0.05. Analysis of the overall survival of patients with cancer of the thoracic part of oesophagus showed that the method of treatment does not have a significant effect on life expectancy. A multivariate analysis of 19 grades that affect the prognosis of the disease was carried out.CONCLUSION:Radical type of treatment of the middle and lower thoracic oesophagus is surgical, in which the median of cumulative survival is 19 months. Traditional radiotherapy should be used in a limited way, as it is palliative, with a median survival of no more than 9 months. The leading factor in the prognosis for thoracic part of oesophagal cancer is the presence of regional metastases, on which the choice of method of treatment depends.

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Op059

Cited by 3 publications

References 0 publications

Clinical case of complications of inguinal node metastatic lesion in gastric cancer after surgical treatment

Clinical case of complications of inguinal node metastatic lesion in gastric cancer after surgical treatment

Risk of recurrence of malignant tumors of the ovaries and levels of tumor markers НЕ-4 and СА-125

Analysis of Treatment Results of the Thoracic Part of Oesophageal Cancer

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