On the role of 2,3-dihydro-3,5-dihydroxy-6-methyl-(4H)-pyran-4-one in antioxidant capacity of prunes

Čechovská, L.; Cejpek, Karel; Konečný, M.; Velı́šek, J.

doi:10.1007/s00217-011-1527-4

Cited by 69 publications

(26 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Additionally, it contains radical scavenging activity compounds such as 13-Tetradecenal. This is because plum, grape and apple seeds have a phenolic composition with antioxidant capacity, comprising 4H-pyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl-and 9,12-octadecadienoic acid (Z, Z)-and phenylmethyl ester [68][69][70][71].…”

Section: Discussionmentioning

confidence: 99%

Screening Pilot Study of Fruit Seed Compositions by GC-MS and Their Potential Scenario Anti ACE2 and 2rh1 Receptors as a Recycling Possibility in the Coronavirus Pandemic

Hamouda¹,

Farawilla²,

Attafi³

et al. 2021

JCMR

View full text Add to dashboard Cite

Background: Since 2019, several critical effects of the coronavirus pandemic have surfaced, including its psychological problems such as depression. The World Health Organization has approved a group of drugs and vaccines. However, the world still faces novel coronavirus mutations, requiring more ideas to investigate a drug, vaccine and phytochemical potential chemoprevention proposal. Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV)-2 co-operates directly with the Angiotensin-Converting Enzyme 2 (ACE2) to penetrate the target cells.Aims: We aim to introduce the possibility of studying seed oil extract as an anti-depression, anti-stress, anti-epinephrine receptor (PDB: 2rh1) and as potentially binding anti-angiotensinconverting enzyme 2 (ACE2) agent.

show abstract

Section: Discussionmentioning

confidence: 99%

Screening Pilot Study of Fruit Seed Compositions by GC-MS and Their Potential Scenario Anti ACE2 and 2rh1 Receptors as a Recycling Possibility in the Coronavirus Pandemic

Hamouda¹,

Farawilla²,

Attafi³

et al. 2021

JCMR

View full text Add to dashboard Cite

show abstract

“…14,37,38 Accordingly, this study has found some known phenolic compounds with anti-oxidant property such as 2,3-Dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one, 39,40 β-tocopherol, 41 pyrogallol (1,2,3,-benzenetriol) 28 and α-tocopherol.…”

mentioning

confidence: 93%

GC-MS Analysis of Phytochemical Compounds in Syzygium polyanthum Leaves Extracted using Ultrasound-Assisted Method

Rahim¹,

Ismail²,

Omar³

et al. 2017

View full text Add to dashboard Cite

Context:Syzygium polyanthum has been traditionally formulated by the folklore for the treatment of diseases including diarrhea, rheumatism, diabetes mellitus, hypercholesterolemia, hypertension, gastritis and hyperuricemia. Normally, its phytochemicals are always extracted using solvent, maceration and steam distillation methods, but the use of ultrasound-assisted extraction (UAE) method is still not well documented. Aims: This study aims to extract the phytochemical compounds present in S. polyanthum leaves using UAE and to identify them by Gas Chromatography-Mass Spectrometry (GC-MS) analysis. Methodology: The leaves were consecutively soaked with n-hexane, ethyl acetate and methanol in a bath sonicator to derive n-hexane (HSP), ethyl acetate (EASP), and methanol (MSP) extracts of S. polyanthum leaves and then the extracts were subjected to GC-MS analysis. Mass-spectral databases of peaks were compared with database from Wiley, NIST and FNSCC libraries for compound identification. Results: GC-MS analyses of HSP, EASP and MSP showed the presence of 21, 27, and 31 peaks, respectively. The major compound for HSP (31.912%), EASP (27.042%), and MSP (22.386%) were unknown compounds which were detected at retention time between 61.980 and 62.29 min, thus requires further characterization. Squalene and phytol were among the other major compounds present in all three extracts. Several identified compounds in the extracts such as squalene, phytol, hentriacontane, palmitic acid, α-pinene, nerolidol, linalool, α-tocopherol and β-tocopherol were known bioactive compounds. analysis of crude methanolic S. polyanthum leaves extract showed the presence of tannins, flavonoids, glycosides, alkaloids, carbohydrates, steroids, triterpenoids and flavonoids. 5,6 Phenolic compounds such as caffeic acid and gallic acid were previously identified in crude macerated methanolic extract of S. polyanthum leaves by high performance liquid chromatography and liquid chromatography mass spectrometry analyses. Conclusion: GC-MS analyses of n-hexane (HSP), ethyl acetate (EASP),7 Analysis on the crude macerated methanolic extract of S. polyanthum leaves has detected squalene as the major compound. 5,8 Another analysis on the macerated n-hexane extract similarly found squalene as the major compound (30.45%) followed by n-hentriacontane (6.57%). 8Most phytochemicals previously studied were extracted using solvent maceration and steam distillation methods, however, the use of ultrasound-assisted extraction (UAE) method is not well-documented. The present study has utilized UAE method, a different extraction method from the other previous studies. Basically, UAE method Rahim et al.: GC-MS Analysis of Syzygium polyanthum Leaves Extracted using Ultrasound-Assisted Extraction MethodPharmacognosy Journal, Vol 10, Issue 1, Jan-Feb, 2018 111 GC conditionThe injector temperature was set at 250 º C, column temperature program was set at 50ºC (0 min) with an increasing rate of 3 º C/min to 300 º C (10 min). The carrier gas used was pure helium gas (9...

show abstract

“…Cardiac glycosides have cardiotonic activity, are antiviral, anticancer and antiproliferative effects [38]. Research findings have reported the anticancer and antimicrobial nature of desulphosinigrin [42]; antioxidant and antifungal activities of 4H-Pyran-4-one,2,3-,dihydro-3,5-dihydroxy-6-methyl- [43][44][45]; 5-Alpha reductase inhibitor, anti-androgenic, anticancer, antioxidant, hypocholesterolemic, acne reductive, anti-inflammatory and antieczemic effect of 9,12-Octadecadienoic acid (Z,Z)- [46][47][48], as well as the anti-inflammatory, anti-cancer, cytotoxic and antimicrobial properties of n-Hexadecanoic acid and Hexadecanoic acid [49][50][51].…”

Section: Discussionmentioning

confidence: 99%

Proximate Analysis and Phytochemical Profile of Brachystegia eurycoma Leaves

Ududua

Monanu

Chuku

2019

AJRB

View full text Add to dashboard Cite

Aim: This study investigated the proximate and phytochemical composition of Brachystegia eurycoma leaves. Methods: Crude ethanol extract of B. eurycoma leaves was obtained by cold extraction method. AOAC method was used for proximate analysis. Phytochemical profiling was done with qualitative phytochemical evaluation and gas chromatography-mass spectrometry (GC/MS) analytical method. Matching and interpretation of the spectral was done with the National Institute standard and Technology (NIST05) library. Results: The proximate analysis result showed B. eurycoma leaves to be abundant in parameters evaluated in the order of 31.47±0.43% Carbohydrate > 15.15±0.04% Ash > 14.45±0.15 crude fibre > 13.83±0.32 protein > 13.14±0.22 moisture > 1.97±0.01 fat. Qualitative phytochemical analysis detected alkaloid, saponin, tannin, diterpenes, phenol, quinine, flavonoid, protein, xanthoprotein and cardiac glycoside in the leaves of B. eurycoma. GC/MS data showed that the prevailing volatile bioactive compounds in ethanol leaf extract of B. eurycoma were 3-O-Methyl-d-glucose (13.23%), cis-9-Hexadecenal (10.40%), Desulphosinigrin (10.34%), Phytol (7.58%), Hydroquinone (7.23%), n-Hexadecanoic acid (6.61%), Oleoyl chloride (6.10%), 9,12-Octadecadienoic acid (Z,Z)- (5.89%), Hexadecanoic acid, (2.97%), Benzofuran, 2,3-dihydro-(1.94%), Hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl) (1.92%). Conclusion: The result of this preliminary investigation reveals the potentials of B. eurycoma leaves as candidate for food, pharmaceutical, cosmetic and nutraceutical industries.

show abstract

On the role of 2,3-dihydro-3,5-dihydroxy-6-methyl-(4H)-pyran-4-one in antioxidant capacity of prunes

Cited by 69 publications

References 31 publications

Screening Pilot Study of Fruit Seed Compositions by GC-MS and Their Potential Scenario Anti ACE2 and 2rh1 Receptors as a Recycling Possibility in the Coronavirus Pandemic

Screening Pilot Study of Fruit Seed Compositions by GC-MS and Their Potential Scenario Anti ACE2 and 2rh1 Receptors as a Recycling Possibility in the Coronavirus Pandemic

GC-MS Analysis of Phytochemical Compounds in Syzygium polyanthum Leaves Extracted using Ultrasound-Assisted Method

Proximate Analysis and Phytochemical Profile of Brachystegia eurycoma Leaves

Contact Info

Product

Resources

About