Olfactory Cleft Disease: An Analysis of 13 Cases

Biacabe, B; Faulcon, P.; Amanou, Laurent; Bonfils, P.

doi:10.1016/j.otohns.2003.09.002

Cited by 31 publications

(26 citation statements)

References 16 publications

(29 reference statements)

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“…This fact has to be taken into account regarding the management of these cases for two reasons. Nasal endoscopy sometimes fails to confirm the presence of polyps in the olfactory area requiring further investigation with a CT scan [26] , and limited surgery can be performed in this area [27] .…”

Section: Discussionmentioning

confidence: 99%

Olfactory Dysfunction in Nasal Polyposis: Correlation with Computed Tomography Findings

Konstantinidis¹,

Triaridis²,

Printza³

et al. 2007

ORL

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Aims: This study evaluates if a computed tomography (CT) scan is useful to assess the olfactory loss in sinonasal disease, and if a preoperative CT scan has a predictive value for the long-term outcome regarding olfaction. Methods: Thirty-one patients with nasal polyposis were included. Olfactory function was assessed with the ‘Sniffin’ Sticks’ test and subjective perception recorded with a visual analogue scale. CT scans were assessed with the Lund-Mackay system and the Damm nasal segmentation. Patients were retested after endoscopic sinus surgery in a follow-up appointment at least 1 year later. Results: Disease in the upper meatus and the posterior portion of the middle meatus strongly affects olfactory function. Lund-Mackay scores were significantly correlated with preoperative olfactory test results. Preoperative subjective ratings had a significant correlation only with present disease in the anterior upper meatus. Postoperative results were significantly decreased. Their relative percentage change was correlated only with the preoperative presence of disease in the anterior upper meatus. No correlation was found between the Lund-Mackay score and the postoperative olfactory results. Conclusions: Olfactory dysfunction in nasal polyposis is strongly related to specific obstructed nasal areas. A CT scan has no predictive value for the long-term surgical outcome regarding olfaction.

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Section: Discussionmentioning

confidence: 99%

Olfactory Dysfunction in Nasal Polyposis: Correlation with Computed Tomography Findings

Konstantinidis¹,

Triaridis²,

Printza³

et al. 2007

ORL

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show abstract

“…The endoscopic examination of the nose must in particular check for polyps or other swellings in the area of the middle turbinate or olfactory cleft region, which can block access of odor molecules to the olfactory epithelium meaning the smell function disappears but the ability to breathe is unimpaired. Such a condition has been described and named “olfactory cleft disease” [78], consisting of an isolated obstruction of the olfactory cleft. This is the reason why rhinomanometry is not entirely useful for evaluating smell function (see also [79]).…”

Section: The Sense Of Smellmentioning

confidence: 99%

Smell and taste disorders

Hummel

Landis²,

Hüttenbrink³

2011

GMS Current Topics in Otorhinolaryngology - Head and Neck Surgery; 10:Doc04; ISSN 1865-1011

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“…Free access of air to the olfactory cleft (OC) is a key element towards maintaining normal olfactory function [1]. Biacabe et al have defined OC disease as an olfactory disability related with a clinical and/or radiologic OC abnormality, involving a pathologic process limited to or predominating in the OC [2]. ey classified the OC disease into 3 groups based on the etiology.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Endoscopic Olfactory Cleft Opening on Obstructed Olfactory Cleft Disease

Jiang

Liang

2020

International Journal of Otolaryngology

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Purpose. This study was conducted to evaluate the effect of endoscopic olfactory cleft (OC) opening on olfaction in patients with obstructed OC disease. Materials and Methods. Patients with obstructed OC disease who underwent endoscopic OC opening for treatment were enrolled. The endoscopic olfactory cleft opening was performed under local anesthesia. Under an endoscopy, the middle and superior turbinates were gently lateralized to open the OC using an elevator. The phenyl ethyl alcohol threshold test was performed to evaluate the olfactory function both before and after surgery. Results. An endoscopic OC opening was performed on 42 patients. Amongst them, the etiology of OC obstruction revealed anatomic anomalies in 14 patients, inflammatory process in 14, and anatomic anomalies as well as inflammatory process in 14. The phenyl ethyl alcohol threshold levels improved in 32 (76.2%) of the patients after surgery. The olfactory function was better improved in patients experiencing OC obstructed by inflammatory process than those by anatomic anomalies. Conclusions. This study showed that endoscopic OC opening seemed to be effective in treating olfactory dysfunction in patients with obstructed OC disease caused by inflammatory process.

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Olfactory Cleft Disease: An Analysis of 13 Cases

Abstract: Olfactory cleft disease involves various pathophysiologic processes. Computed tomography scanning provides the most information for diagnosis. Indications of functional endoscopic surgery remain to be defined after failure of medical therapy.

Cited by 31 publications

References 16 publications

Olfactory Dysfunction in Nasal Polyposis: Correlation with Computed Tomography Findings

Olfactory Dysfunction in Nasal Polyposis: Correlation with Computed Tomography Findings

Smell and taste disorders

The Effect of Endoscopic Olfactory Cleft Opening on Obstructed Olfactory Cleft Disease

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