Olfactory Dysfunction in Nasal Polyposis: Correlation with Computed Tomography Findings

Konstantinidis, Iordanis; Triaridis, Stefanos; Printza, Athanasia; Vital, Victor; Ferekidis, Eleftherios; Constantinidis, Jannis

doi:10.1159/000101543

Cited by 42 publications

(45 citation statements)

References 53 publications

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“…Two studies did not find any association between age and olfactory dysfunction . Within CRS‐specific factors, a higher Lund‐Mackay (LM) computed tomography (CT) score was most frequently associated with poorer smell with 11 studies reporting this relationship . Remaining studies did not examine this association.…”

Section: Resultsmentioning

confidence: 98%

“…Three studies in CRS mixed and two studies in chronic rhinosinusitis without nasal polyps (CRSsNP) presented modified 12‐odor identification scores, yielding a population of 245 and 53 patients, respectively. Olfaction is classified using the 12‐odor Sniffin' Sticks identification test as: 0 to 6 anosmic, 7 to 10 hyposmic, and 11 to 12 normosmic .…”

Section: Resultsmentioning

confidence: 99%

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The prevalence of olfactory dysfunction in chronic rhinosinusitis

et al. 2016

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Objective Many studies have reported that olfactory dysfunction frequently occurs in chronic rhinosinusitis (CRS) populations; however, the prevalence and degree of olfactory loss has not been systematically studied. The aims of this study are to use combined data to report the prevalence of olfactory dysfunction and to calculate weighted averages of olfactory test scores in CRS patients. Data Sources A search was conducted in PubMed and Scopus, following the methods of Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines. Review Methods Studies reporting the prevalence of olfactory dysfunction using objective measures or olfactory test scores using validated scales were included. Results A total of 47 articles were included in systematic review and 35 in the pooled data analysis. The prevalence of olfactory dysfunction in chronic rhinosinusitis was found to be 30.0% using the Brief Smell Identification Test, 67.0% using the 40-item Smell Identification Test, and 78.2% using the total Sniffin’ Sticks score. Weighted averages ± standard deviation of olfactory test scores were 25.96±7.11 using the 40-item Smell Identification Test, 8.60±2.81 using the Brief Smell Identification Test, 21.96±8.88 using total Sniffin’ sticks score, 5.65±1.51 using Sniffin’ Sticks threshold, 9.21±4.63 using Sniffin’ Sticks discrimination, 9.47±3.92 using Sniffin’ Sticks Identification, and 8.90±5.14 using the questionnaire for olfactory disorders-negative statements. Conclusion In chronic rhinosinusitis populations, a significant percentage of patients experience olfactory dysfunction and mean olfactory scores are within the dysosmic range.

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Section: Resultsmentioning

confidence: 98%

Section: Resultsmentioning

confidence: 99%

The prevalence of olfactory dysfunction in chronic rhinosinusitis

et al. 2016

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“…After close evaluation of the publications, 24 studies reached the inclusion criteria for this review. These have been published over the last 20 years and used the USPIT or single components or the whole battery of the Sniffin’ Sticks test . Almost all the included studies were published in the period from 2007 to 2018; only one earlier study from 1994 was identified …”

Section: Resultsmentioning

confidence: 99%

Recovery of olfaction after sinus surgery for chronic rhinosinusitis: A review

Haxel

2019

The Laryngoscope

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Objective Investigation of the postoperative olfactory function after sinus surgery for chronic rhinosinusitis (CRS) with and without polyps in a review. Data Sources PubMed. Review Methods A comprehensive literature search was conducted through June 2018 using relevant keywords. The titles/abstracts were reviewed to identify studies evaluating the sense of smell in CRS‐patients pre‐ and postoperatively by either using the whole or parts of the University of Pennsylvania Smell Identification Test or the Sniffin’ Sticks test. Study characteristics and outcome data of the included studies were extracted. Results In total, 106 studies were retrieved. Twenty‐four studies comprising 1,956 patients were included after quality assessment. The number of patients investigated per study was 19 to 206. In the 24 studies, 959 patients with nasal polyps and 516 without nasal polyps were described. The follow‐up times varied between 0.5 and 28 months. Twenty‐three studies reported an improved sense of smell, at least in certain subgroups. An overall improvement was seen in approximately 50% of the included patients. Nasal polyposis and preoperative anosmia were associated with a higher chance of improvement in olfaction. In those studies that commented on deterioration after sinus surgery, a decrease in olfaction was found in a range from 0% to 10% of cases. Conclusion Olfaction can be improved by sinus surgery in about every second patient, especially if the patient had chronic rhinosinusitis with polyps, was anosmic, and had no prior surgery. A deterioration of sense of smell after surgery is rare. Laryngoscope, 129:1053–1059, 2019

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“…3,22,23 Similarly, the predictive value of CT seems to be limited and controversial in terms of both olfactory and endoscopic examination. [24][25][26][27] Most of the existing studies have used the patient's subjective evaluation of symptoms to assess the clinical outcomes after FESS with questionnaires on several patient-evaluated symptoms, without targeting olfactory performance. 3,5,6 Individuals, however, seem to vary in their awareness of changes in olfactory sensitivity and only 84% of the patients with impaired sense of smell seem to be aware of their problem.…”

Section: Between the Different Time Frames Within Each Group (One-waymentioning

confidence: 99%