2009
DOI: 10.2500/ajra.2009.23.3325
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Allergic Rhinitis and Aspirin-Exacerbated Respiratory Disease as Predictors of the Olfactory Outcome after Endoscopic Sinus Surgery

Abstract: The olfactory recovery after FESS for nasal polyposis is significantly affected by the concomitant presence of AERD. Although allergy seems to have a general negative effect on olfactory acuity, it was not found to affect the extent of the olfactory improvement, when patients with comparable preoperative characteristics are addressed.

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Cited by 31 publications
(28 citation statements)
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References 32 publications
(48 reference statements)
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“…In this study, we observed that AERD patients have significantly higher SNOT-20 GAV scores when compared to CRSwNP or CRSsNP. This is in accordance with previous data showing that QoL and olfactory function of AERD patients is more compromised when compared to those CRS patients who are not aspirin-intolerant [21,23]. In our analysis of the various subcategories of the SNOT-nasal, otologic, sleep, and emotional symptoms-it became evident that the different SNOT outcome is mainly due to nasal symptom burden.…”
Section: Discussionsupporting
confidence: 92%
See 1 more Smart Citation
“…In this study, we observed that AERD patients have significantly higher SNOT-20 GAV scores when compared to CRSwNP or CRSsNP. This is in accordance with previous data showing that QoL and olfactory function of AERD patients is more compromised when compared to those CRS patients who are not aspirin-intolerant [21,23]. In our analysis of the various subcategories of the SNOT-nasal, otologic, sleep, and emotional symptoms-it became evident that the different SNOT outcome is mainly due to nasal symptom burden.…”
Section: Discussionsupporting
confidence: 92%
“…In this respect, patients with non-type 2 disease or CRSsNP suffer from fewer recurrences of the disease after surgical treatment and have a lower incidence of comorbidities than seen in type-2 inflammation or CRSwNP [4]. Furthermore, patients with AERD have a higher endoscopic polyp score [21], greater impairment of olfactory function [22,23], and a higher risk of revision surgery when compared to those suffering from nasal polyposis alone [24,25]. However, despite clear differences in CRS subtypes, studies evaluating whether this is also reflected in QoL outcomes are missing.…”
Section: Introductionmentioning
confidence: 99%
“…However, a recent study has reported that patients with asthma, CRSwNP, and aspirin sensitivity have postoperative quality of life outcomes that are comparable to patients with CRSwNP who are not aspirin sensitive [27]. The olfactory recovery after FESS for CRSwNP is significantly affected by the concomitant presence of AERD [32].…”
Section: Extent Of Disease At Baseline and Comorbiditiesmentioning
confidence: 95%
“…The recovery of a normal sense of smell after medical and surgical treatment appears to be less likely in AERD patients compared with patients with allergic rhinitis. 8 Recurrence of nasal polyps after medical or surgical treatment is typical in AERD patients and has been reported to be nearly three times higher than in aspirin-tolerant asthmatic patients. 9 …”
Section: Natural Historymentioning
confidence: 99%