Newly synthesized poly(glycidyl methacrylate-co-3-thienylmethylmethacrylate)-based electrode designs for phenol biosensors

Poly(glycidyl methacrylate‐co‐3‐thienyl‐methylmethacrylate) based working electrodes for hydrogen peroxide biosensing

“…13,14,16,17 Electrochemical characterization of Poly(GMA-co-MTM) based electrodes We previously reported that, when an electrode surface was coated with Poly(GMA-co-MTM) only, the electrode showed no response to phenolic compounds, and did not show any electroactivity unless a conductive polymer was joined to the Poly(GMA-co-MTM) side chain via the thiophene groups. Therefore, we proposed to fabricate a conductive composite form of Poly(GMA-co-MTM) with polypyrrole to prevent this drawback.…”

“…Therefore, we proposed to fabricate a conductive composite form of Poly(GMA-co-MTM) with polypyrrole to prevent this drawback. 17 CVs of Poly(GMA 90% -co-MTM 10% )/PPy/HRP, Poly(GMA 85% -co-MTM 15% )/PPy/HRP and Poly(GMA 30% -co-MTM 70% )/PPy/HRP working electrodes are presented in Fig. 1 (only the final cycles are shown).…”

“…Poly(GMA-co-MTM) compositions, including GMA and MTM monomers of various amounts, were synthesized via radical polymerization of appropriate GMA/MTM feed mixtures in the presence of AIBN as an initiator as described in the literature. 16,17 Monomer compositions of the copolymers were determined using photometric analysis with a Shimadzu UV-3600 UV-VIS-NIR spectrometer in THF solutions. Molecular weights and molecular weight distributions of the polymers were measured on an Agilent Instrument (Model 1100) consisting of a pump, a refractive index detector, and four Waters Styragel columns (HR 5E, HR 4E, HR3, and HR 2) using THF as eluent at a flow rate of 0.3 mL min −1 at 30 • C and toluene as an internal standard.…”

“…13 -16 Although, Poly(GMA-co-MTM) has no electroactivity the final polymeric film obtained through the electropolymerization process between thiophene and a conductive polymer becomes a conductive copolymer. 17 Various architectures of epoxy group possessing polymers have been developed. 13,14 Copolymers of glycidyl methacrylate (GMA), an epoxy group containing methacrylate monomer, with other acrylic or vinyl monomers have created great interest because of the pendant epoxide groups.…”

Enzyme based phenol biosensors

“…Theoretically, it is possible for an enzyme molecule to bind to the composite film through the two different mechanisms simultaneously. Such multiple linkages might be resulted an increased steric hindrance on the enzyme molecule (Korkut Ozoner et al, 2010;Bayramoğlu & Yakup Arıca, 2008). Moreover, Kobayashi et al 2005 reported that their results suggested the magnitude of the effect of steric hindrance depended on the disubstitution of phenol derivatives (Kobayashi et al, 2005).…”