Neck circumference in relation to glycemic parameters: a systematic review and meta-analysis of observational studies

Saneei, Parvane; Shahdadian, Farnaz; Moradi, Sajjad; Ghavami, Abed; Mohammadi, Hamed

doi:10.1186/s13098-019-0445-7

Cited by 24 publications

(16 citation statements)

References 48 publications

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“…Another advantage of NC is that the measurement does not require undressing or any mobilization, which protects patient privacy and saves time in anthropometric explorations. Moreover, another study compared the correlation of different anthropometric indicators including BMI, WC, and NC with HOMA-IR, and the results showed that NC outstripped other anthropometric measurements in prediction of IR (26,32). Similar results also were observed in a Turkish Adult Cohort Study in 1,912 middle-aged and elderly individuals and a study with overweight adults (33).…”

Section: Figuresupporting

confidence: 58%

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Neck circumference is a good predictor for insulin resistance in women with polycystic ovary syndrome

Chen

Zheng

et al. 2021

Fertility and Sterility

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Objective: To assess the role of neck circumference (NC) in assessing insulin resistance (IR) in polycystic ovary syndrome (PCOS). Design: A cross-sectional study. Setting: University-affiliated hospital. Patient(s): One hundred forty-three women with PCOS were recruited from November 2018 to February 2020. Intervention(s): None. Main Outcome Measure(s): The associations of NC with IR and the cutoff points of NC for IR. Result(s): The prevalence rates of IR were 64.3%. The patients with PCOS with IR had significantly greater values of systolic blood pressure, NC, body mass index, waist-to-hip ratio, waist circumference, fasting blood glucose, fasting insulin, and homeostasis model assessment of insulin resistance (HOMA-IR). Pearson correlation analysis showed body mass index (log-transformed), waist circumference, waist-to-hip ratio, and HOMA-IR (log-transformed) were positively correlated with NC. Multivariable linear regression showed that NC was significantly associated with HOMA-IR (log-transformed), with the standardized regression coefficient of 0.330 with adjustment for potential confounding factors. Furthermore, multivariate logistic regression analyses showed NC was associated significantly with increased risk of IR, with the adjusted odds ratio of 1.423. Additionally, NC was able to identify IR in women with PCOS; the optimal cut-off points was 34.3 cm (Youden index ¼ 0.586). Conclusion(s):Neck circumference is positively associated with IR in women with PCOS. We suggest NC as a novel, simple, practical, and reliable anthropometric measure to be used to predict the risk of IR in patients with PCOS. (Fertil Steril Ò 2021;115:753-60. Ó2020 by American Society for Reproductive Medicine.) El resumen está disponible en Español al final del artículo.

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Section: Figuresupporting

confidence: 58%

“…Fertil Steril 2020. 26). In addition, a large study from Brazil showed a significant association between NC and IR and determined the cut-off value of the NC for the prediction of IR (20).…”

Section: Figurementioning

confidence: 99%

Neck circumference is a good predictor for insulin resistance in women with polycystic ovary syndrome

Chen

Zheng

et al. 2021

Fertility and Sterility

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“…Studies in Asia reported a mean NC between 31cm and 44cm 102 , 103 . Our pooled estimates fall within this range.…”

Section: Discussionmentioning

confidence: 99%

“…NC has been associated with several cardiometabolic risk factors: insulin resistance, elevated cholesterol, triglycerides, LDL-cholesterol and obesity 102 , 103 . Moreover, NC has also been associated with SAHOS 104 .…”

Section: Discussionmentioning

confidence: 99%

Neck circumference in Latin America and the Caribbean: A systematic review and meta-analysis

López¹,

Landeo²,

Mercado³

et al. 2021

Wellcome Open Res

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Background: High neck circumference (NC) is associated with high burden diseases in Latin American and the Caribbean (LAC). NC complements established anthropometric measurements for early identification of cardio-metabolic and other illnesses. However, evidence about NC has not been systematically studied in LAC. We aimed to estimate the mean NC and the prevalence of high NC in LAC. Methods: We conducted a systematic review in MEDLINE, Embase, Global Health and LILACS. Search results were screened and studied by two reviewers independently. To assess risk of bias of individual studies, we used the Hoy et al. scale and the Newcastle-Ottawa scale. We conducted a random-effects meta-analysis. Results: In total, 182 abstracts were screened, 96 manuscripts were reviewed and 85 studies (n= 51,978) were summarized. From all the summarized studies, 14 were conducted in a sample of the general population, 23 were conducted with captive populations and 49 studies were conducted with patients. The pooled mean NC in the general population was 35.69 cm (95% IC: 34.85cm-36.53cm; I²: 99.6%). In our patient populations, the pooled mean NC in the obesity group was 42.56cm (95% CI 41.70cm-43.42cm; I²: 92.40%). Across all studied populations, there were several definitions of high NC; thus, prevalence estimates were not comparable. The prevalence of high NC ranged between 37.00% and 57.69% in the general population. The methodology to measure NC was not consistently reported. Conclusions: Mean NC in LAC appears to be in the range of estimates from other world regions. Inconsistent methods and definitions hamper cross-country comparisons and time trend analyses. There is a need for consistent and comparable definitions of NC so that it can be incorporated as a standard anthropometric indicator in surveys and epidemiological studies.

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“…Several anthropometric indexes, such as waist‐to‐hip ratio, BMI, waist circumference and neck circumference (NC) are used to evaluate and estimate the ‘adiposity’ 12 . Many studies have shown that upper‐body obesity has a stronger association with cardiometabolic conditions compared to lower‐body obesity 13,14 . NC, as an index for upper‐body subcutaneous adipose tissue distribution, has been shown to be strongly related to insulin resistance, 15 early stage atherosclerosis, 16 diabetes, 17 coronary heart diseases 18 and cardiometabolic syndrome even after adjustment for visceral adipose tissue and BMI 19 .…”

Section: Introductionmentioning

confidence: 99%

Neck circumference as reliable predictor of mechanical ventilation support in adult inpatients with COVID‐19: A multicentric prospective evaluation

Bella

Cesareo

Cristofaro³

et al. 2020

Diabetes Metabolism Res

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AimsCOVID‐19 is especially severe for elderly subjects with cardiometabolic and respiratory comorbidities. Neck circumference (NC) has been shown to be strongly related to cardiometabolic and respiratory illnesses even after adjustment for body mass index (BMI). We performed a prospective study to investigate the potential of NC to predict the need for invasive mechanical ventilation (IMV) in adult COVID‐19 inpatients.Materials and MethodsWe prospectively and consecutively enrolled COVID‐19 adult patients admitted to dedicated medical wards of two Italian hospitals from 25 March to 7 April 2020. On admission, clinical, biochemical and anthropometric data, including BMI and NC were collected. As primary outcome measure, the maximum respiratory support received was evaluated. Follow‐up time was 30 days from hospital admission.ResultsWe enrolled 132 subjects (55.0‐75.8 years, 32% female). During the study period, 26 (19.7%) patients underwent IMV. In multivariable logistic regression analyses, after adjusting for age, sex, diabetes, hypertension and COPD, NC resulted independently and significantly associated with IMV risk (adjusted OR 1.260—per 1 cm increase 95% CI:1.120‐1.417; P < .001), with a stronger association in the subgroup with BMI ≤30 Kg/m2 (adjusted OR 1.526; 95% CI:1.243‐1.874; P < .001). NC showed a good discrimination power in predicting patients requiring IMV (AUC 0.783; 95% CI:0.684‐0.882; P < .001). In particular, NC > 40.5 cm (>37.5 for females and >42.5 for males) showed a higher and earlier IMV risk compared to subjects with lower NC (Log‐rank test: P < .001).ConclusionsNC is an easy to measure parameter able to predict the need for IMV in adult COVID‐19 inpatients.

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Neck circumference in relation to glycemic parameters: a systematic review and meta-analysis of observational studies

Cited by 24 publications

References 48 publications

Neck circumference is a good predictor for insulin resistance in women with polycystic ovary syndrome

Neck circumference is a good predictor for insulin resistance in women with polycystic ovary syndrome

Neck circumference in Latin America and the Caribbean: A systematic review and meta-analysis

Neck circumference as reliable predictor of mechanical ventilation support in adult inpatients with COVID‐19: A multicentric prospective evaluation

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