Nanomaterial Based Biosensors for Detection of Viruses Including SARS-CoV-2: A Review

Bisht, Ayushi; Mishra, Abhishek; Bisht, Harender S.; Tripathi, Ravi Mani

doi:10.1007/s41664-021-00200-0

Cited by 49 publications

(29 citation statements)

References 104 publications

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“…Although enormous success in sensing based on MOF/AuNCs assemblies has been achieved, some challenges still remain to be dealt with. Firstly, efforts will be worthwhile to expand the scope of detectable analytes, such as bacteria [ 137 ], virus (e.g., coronavirus COVID-19) [ 138 ], volatile organic compounds (e.g., aliphatic and aromatic hydrocarbons, aldehydes) and toxic gases (e.g., NH 3 , SO 2 , NO x , CS 2 ) [ 60 ]. Secondly, the integration of MOFs with ultrasmall-sized AuNCs provides great opportunities for sensing application beyond the present advances, which have not been exploited adequately yet.…”

Section: Discussionmentioning

confidence: 99%

Metal–Organic Frameworks-Mediated Assembly of Gold Nanoclusters for Sensing Applications

Wang

Tan

et al. 2022

J. Anal. Test.

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Gold nanoclusters (AuNCs) are an emerging type of ultrasmall nanomaterials possessing unique physicochemical characteristics. Metal–organic frameworks (MOFs), a singular kind of porous solid and crystalline material, have attracted tremendous attention in recent years. The combination of AuNCs and MOFs can integrate and improve the prominent properties of both components, such as high catalytic activities, tunable optical properties, good biocompatibility, surface functionality and stability, which make the composites of MOFs and AuNCs promising for sensing applications. This review systematically summarizes the recent progress on the sensing of various analytes via MOFs-mediated AuNCs assemblies based on strategies of luminescence sensing, colorimetric sensing, electrochemiluminescence sensing, and electrochemical and photoelectrochemical sensing. A brief outlook regarding the future development of MOFs-mediated AuNCs assemblies for sensing application is presented as well.

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Section: Discussionmentioning

confidence: 99%

Metal–Organic Frameworks-Mediated Assembly of Gold Nanoclusters for Sensing Applications

Wang

Tan

et al. 2022

J. Anal. Test.

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“…Carbon nanotubes (CNTs) exhibit limitations in terms of toxicity for the treatment of COVID-19 (Sadighbayan et al, 2020;Jeong et al, 2021;Joshi et al, 2021). When exposed to the lungs, they activate macrophages in the lower respiratory tract, causing fibrosis and collagen formation in the lesions (Bisht et al, 2021;Galal et al, 2021;Özmen et al, 2021). Lipid-coated MSNPs containing antiviral agent (ML336) were developed as a strategy to improve antiviral circulation time and biocompatibility.…”

Section: Nanomaterial-based Drug Delivery Systemsmentioning

confidence: 99%

Nanotechnology and COVID-19: Prevention, diagnosis, vaccine, and treatment strategies

Ayan

Aranci-Ciftci²,

Çiftçi³

et al. 2023

Front. Mater.

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In December 2019, Coronavirus pandemic (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) viruses, which affected the whole world, is emerged. The details on the epidemiology, infection source, transmission mode, and prognosis of SARS-CoV-2 gave in this review. Universal infection control standards such as hand hygiene, environmental cleanliness, use of personal protective equipment, and quarantine used to prevent the spread of COVID-19 without vaccine. However, many vaccine candidate studies carried out globally with using traditional and technological approaches. Innovations in technology allow the development of nanotechnological tools and the formation of systems that will inactivate SARS-CoV-2 in patients. It expected to include technologies that combine different disciplines, especially robotic applications, antimicrobial nanotechnology, and tissue engineering for the future treatment of COVID-19. This review-based work discusses the relationship of COVID-19 and nanotechnology based working principles.

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“…In pandemic-like circumstances, mass-scale, on-the-spot primary testing of pretreatmentfree samples using a reusable biosensor has great promise [101]. A unique portable handheld analyzer comprising a nanomaterial-based hybrid sensor array with multiplexed capabilities was reported for the detection and monitoring of COVID-19-specific volatile organic compounds (VOCs) from the exhaled breath (Figure 3C) [98].…”

Section: Chip-based Electrochemical Antigen Detectionmentioning

confidence: 99%

A Review on Potential Electrochemical Point-of-Care Tests Targeting Pandemic Infectious Disease Detection: COVID-19 as a Reference

et al. 2022

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Fast and accurate point-of-care testing (POCT) of infectious diseases is crucial for diminishing the pandemic miseries. To fight the pandemic coronavirus disease 2019 (COVID-19), numerous interesting electrochemical point-of-care (POC) tests have been evolved to rapidly identify the causal organism SARS-CoV-2 virus, its nucleic acid and antigens, and antibodies of the patients. Many of those electrochemical biosensors are impressive in terms of miniaturization, mass production, ease of use, and speed of test, and they could be recommended for future applications in pandemic-like circumstances. On the other hand, self-diagnosis, sensitivity, specificity, surface chemistry, electrochemical components, device configuration, portability, small analyzers, and other features of the tests can yet be improved. Therefore, this report reviews the developmental trend of electrochemical POC tests (i.e., test platforms and features) reported for the rapid diagnosis of COVID-19 and correlates any significant advancements with relevant references. POCTs incorporating microfluidic/plastic chips, paper devices, nanomaterial-aided platforms, smartphone integration, self-diagnosis, and epidemiological reporting attributes are also surfed to help with future pandemic preparedness. This review especially screens the low-cost and easily affordable setups so that management of pandemic disease becomes faster and easier. Overall, the review is a wide-ranging package for finding appropriate strategies of electrochemical POCT targeting pandemic infectious disease detection.

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Nanomaterial Based Biosensors for Detection of Viruses Including SARS-CoV-2: A Review

Cited by 49 publications

References 104 publications

Metal–Organic Frameworks-Mediated Assembly of Gold Nanoclusters for Sensing Applications

Metal–Organic Frameworks-Mediated Assembly of Gold Nanoclusters for Sensing Applications

Nanotechnology and COVID-19: Prevention, diagnosis, vaccine, and treatment strategies

A Review on Potential Electrochemical Point-of-Care Tests Targeting Pandemic Infectious Disease Detection: COVID-19 as a Reference

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