Nanotechnology and COVID-19: Prevention, diagnosis, vaccine, and treatment strategies

Ayan, Sümeyra; Aranci-Ciftci, Kubra; Çiftçi, Fatih; Üstündağ, Cem Bülent

doi:10.3389/fmats.2022.1059184

Cited by 4 publications

(13 citation statements)

References 259 publications

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“…Only when herd immunity develops, as a result of an efficient vaccination or if the population has already been exposed and is resistant to reinfection, will COVID-19 be suppressible. Until there is a successful vaccination, there is almost little hope of a return to pre-COVID-19 social behavior [66,68]. Antiviral drugs and other sorts of drugs that prevent viral replication may be delivered via nanotechnology.…”

Section: ■ Nanomaterials For Subunit Dna and Rna Covid-19 Vaccinementioning

confidence: 99%

Nanomaterial for Adjuvants Vaccine: Practical Applications and Prospects

Tran,

Vo,

Dang

et al. 2024

Indones. J. Chem.

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Vaccines contain adjuvants to strengthen the immune responses of the receiver against pathogen infection or malignancy. A new generation of adjuvants is being developed to give more robust antigen-specific responses, specific types of immune responses, and a high margin of safety. By changing the physical and chemical properties of nanomaterials, it is possible to make antigen-delivery systems with high bioavailability, controlled and sustained release patterns, and the ability to target and image. Nanomaterials can modulate the immune system so that cellular and humoral immune responses more closely resemble those desired. The use of nanoparticles as adjuvants is believed to significantly improve the immunological outcomes of vaccination because of the combination of their immunomodulatory and delivery effects. In this review, we discuss the recent developments in new adjuvants using nanomaterials. Based on three main vaccines, the subunit, DNA, and RNA vaccines, the possible ways that nanomaterials change the immune responses caused by vaccines, such as a charge on the surface or a change to the surface, and how they affect the immunological results have been studied. This study aims to provide succinct information on the use of nanomaterials for COVID-19 vaccines and possible new applications.

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Section: ■ Nanomaterials For Subunit Dna and Rna Covid-19 Vaccinementioning

confidence: 99%

Nanomaterial for Adjuvants Vaccine: Practical Applications and Prospects

Tran,

Vo,

Dang

et al. 2024

Indones. J. Chem.

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show abstract

“…Angiotensin-converting enzyme 2 (ACE2) receptors allow COVID-19 viruses to enter cells, so lowering ACE2 levels could help cut down on the number of infections. It was suggested that using nanotechnology in the gloves to catch the viruses before they enter the cells would be very beneficial [ 4 ].…”

Section: Reviewmentioning

confidence: 99%

“…The vaccines have been developed and tested at an unprecedented pace, thanks to advancements in biomedical science. This has been a significant achievement, and it provides hope for the control of other infectious diseases in the future [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Emerging Applications of Biomedical Science in Pandemic Prevention and Control: A Review

Weerarathna,

Luharia,

Tivaskar

et al. 2023

Cureus

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The COVID-19 pandemic has made it abundantly clear how crucial biomedical science is to pandemic control and prevention on a global scale. The importance of biomedical science in the fight against pandemics has increased with the appearance of new, deadly infectious diseases. Biomedical science and engineering have been presented as possible areas for combating the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) due to the unique challenges raised by the pandemic, as reported by epidemiologists, immunologists, and doctors, including the survival, symptoms, protein surface composition, and infection mechanisms of COVID-19. These multidisciplinary engineering concepts are applied to design and develop prevention methods, diagnostics, monitoring, and therapies. An infectious disease outbreak that has spread over a sizable region, such as several continents or the entire world, and is affecting a sizable number of people is referred to as a "pandemic. While current knowledge about the SARS-CoV-2 virus is still limited, various (old and new) biomedical approaches have been developed and tested. Here, we review the emerging applications of biomedical science in pandemic prevention and control, including rapid diagnosis tests, the development of vaccines, antiviral therapies, artificial intelligence, genome sequencing, and personal protective equipment. Biomedical science and nanotechnology are two fields that have the potential to combine to develop emerging applications for combating pandemics. In this review, we also discuss the intersection of biomedical science and nanotechnology in pandemic prevention and control.

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“…The genomic structure of the SARS-CoV-2 virus has been found to have a 79.5% match with the SARS-CoV-1 virus which was the causative agent of an epidemic in the year 2002 [3,4]. In addition, the SARS-CoV-2 virus exhibits a 96% genome similarity to RaTG13 which is a species of a bat coronavirus [3,4,6]. As validated by evolutionary research and due to the genomic similarity, the bat is now considered to be the main biological host of SARS-CoV-2 virus.…”

Section: Introductionmentioning

confidence: 98%

“…As validated by evolutionary research and due to the genomic similarity, the bat is now considered to be the main biological host of SARS-CoV-2 virus. In order to successfully prevent and manage COVID-19 infections, there is need to understand it's viral protein structure as well as the links between its functions and the interactions with the human host machinery during pathogenesis [4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

A Concise Review of The Role of Nanotechnology, Nanoparticles and Nanomedicine Play in The Diagnostics, Vaccination and Treatment Options For COVID-19

Sharma¹

2023

IJOPRS

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Since the end of 2019, we have been combating the health challenges caused by the multiple waves of COVID-19 (coronavirus disease 2019) pandemic caused by the mutated variants of concern of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The key to successfully combating the COVID-19 pandemic remains prevention by vaccination, rapid as well as timely detection and diagnosis, with proper treatment of infection cases. The previously used and standardized viral diagnostics and therapeutics have not been effective in combating the SARS-CoV-2 virus as observed during this ongoing COVID-19 pandemic. Nanotechnology and it's applications in nanomedicine have been very effective and valuable as applied in drug delivery, vaccines and nanosensor technology in various diseases. In the last three years, nanotechnology, nanoparticles and nanomedicine have played a very significant role in the prevention, diagnostics, treatment options and vaccination associated with the COVID-19 infection. In this concise review, the most recent developments on the role played by nanotechnology, nanoparticles and nanomedicine in the diagnostics, vaccination and treatment options for COVID-19 have been highlighted. .

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Nanotechnology and COVID-19: Prevention, diagnosis, vaccine, and treatment strategies

Cited by 4 publications

References 259 publications

Nanomaterial for Adjuvants Vaccine: Practical Applications and Prospects

Nanomaterial for Adjuvants Vaccine: Practical Applications and Prospects

Emerging Applications of Biomedical Science in Pandemic Prevention and Control: A Review

A Concise Review of The Role of Nanotechnology, Nanoparticles and Nanomedicine Play in The Diagnostics, Vaccination and Treatment Options For COVID-19

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