Multifocal epithelial hyperplasia in a community in the Mayan area of Mexico

Gonzalez-Losa, M.R.; Suarez-Allén, Rosa E; Canul-Canche, Jaqueline; Conde-Ferráez, Laura; Eljure-Lopez, Nixma

doi:10.1111/j.1365-4632.2010.04718.x

Cited by 20 publications

(19 citation statements)

References 21 publications

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“…We found no difference in age distribution for HPV prevalence or for clinical manifestations of FEH. However, the age range was 6-14 years of age; perhaps on a larger range of ages there would be an apparent age group with a higher prevalence of FEH [9]. Also, we found no difference in gender prevalence (Figure 4).…”

Section: Elementarycontrasting

confidence: 37%

“…HPV has been previously isolated in saliva [9] of patients with FEH and even though all three schools are at risk of saliva transmission, the prevalence of HPV-13 positive samples were inversely proportional to the income level of the elementary schools, with a higher prevalence in the LI elementary.…”

Section: Discussionmentioning

confidence: 89%

“…This study took place in a rural Mayan community previously studied epidemiologically for the evidence of presence of Heck's disease [9]. The scope of the present study is to document the prevalence of Heck's disease in a rural community with an important indigenous population and compare it to an urban community with a more mestizo population.…”

Section: Introductionmentioning

confidence: 99%

“…Also we seek to molecularly determine the presence of HPV-13 in patients with and without lesions clinically compatible with Heck's disease. Previously described risk factors also include indigenous ethnic heritage, lower economic status, family history of the disease, and malnutrition [9].…”

Section: Introductionmentioning

confidence: 99%

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Focal Epithelial Hyperplasia Prevalence in an Endemic Population, Molecular Association of HPV-13 to Asymptomatic Patients and Comparison Between Three Elementary Schools of Different Income Levels

Zavala-Garcia¹,

Briceño-Mena²,

Romero-Beltran³

et al. 2017

J immuno Biol

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Heck's disease, or Focal Epithelial Hyperplasia (FEH), caused by Human Papilloma Virus (HPV) subtypes 13 and mainly 32, is a rare and benign pathology of the oral mucosa; diagnosis is confirmed by PCR analysis. This is a common disease in the Mayan and other Native-American populations, most frequently between 2-13 years. Risk factors include lower income class, poor hygiene and genetic predisposition.This cross-sectional study aims to determine the prevalence of clinically compatible lesions of FEH in children from low, middle and high-income in 3 elementary schools in Yucatan, Mexico.Clinical evaluation was conducted and documented for later analysis by a dermatologist familiar with FEH. Samples were taken and HPV-13 was identified by PCR.The total of 186 subjects were analyzed from the low-income elementary school, with 41 subjects presenting FEH lesions and 76 presented HPV-13 upon PCR analysis. In the middle-income school, of the 144 subjects studied, 3 had FEH lesions and 8 presented HPV-13 upon PCR analysis. In the high-income elementary school, 96 students were studied, and none presented FEH lesions, however, 6 had HPV-13 positivity.FEH and HPV-13 prevalence were inversely proportional to socioeconomic status. Lacking an association to a particular gender or difference in the age groups studied.

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Section: Elementarycontrasting

confidence: 37%

Section: Discussionmentioning

confidence: 89%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Focal Epithelial Hyperplasia Prevalence in an Endemic Population, Molecular Association of HPV-13 to Asymptomatic Patients and Comparison Between Three Elementary Schools of Different Income Levels

Zavala-Garcia¹,

Briceño-Mena²,

Romero-Beltran³

et al. 2017

J immuno Biol

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“…Como se muestra en la Figura 3 es una patología benigna de la mucosa oral, caracterizada por lesiones múltiples, bien definidas, de un tamaño aproximado de 5 mm, estas lesiones se presentan a manera de pápulas o placas del mismo color de la mucosa oral. Afecta labios, margen lateral de la lengua, así como la mucosa, su crecimiento es lento, y principalmente se presentan en niños de ambos sexos (González-Losa et al, 2011). Estas lesiones se han reportado sobretodo en grupos étnicos latinoamericanos, se han asociado a múltiples factores tales como predisposición genética, desnutrición, higiene y las condiciones de vivienda de las personas afectadas (Carlos & Sedano, 1994).…”

Section: Alto Riesgo Bajo Riesgounclassified

Presencia del Virus Papiloma Humano en la Cavidad Oral: Revisión y Actualización de la Literatura

Atienzo

Memije

Galván

et al. 2015

Int. J. Odontostomat.

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RESUMEN:El virus del papiloma humano (VPH) forma parte de un grupo de virus ADN heterogéneo llamados papillomaviridae; este virus es causante de múltiples lesiones hiperplásicas, verrucosas y papilomatosas de las células epiteliales de piel y mucosas, existen más de 120 tipos de VPH, de solo 100 se conoce su secuencia genómica completa. Los dos géneros más importantes son los papilomavirus alpha (∂) y los beta (ß), la mayoría de los virus que infectan el área genital pertenecen al género alpha; según sus características clínicas, se pueden subdividir en cutáneos y de mucosa. Si bien las infecciones por este virus son frecuentes en cavidad oral, este campo de la medicina se encuentra en estudio, debido a que la información sobre el tema no es concluyente, es prioritario para el estomatólogo conocer las generalidades acerca del VPH y tratar las lesiones de una manera informada, este virus se asocia a un 35% de los casos de cáncer de cavidad oral, de los cuales el 70% de ellos son de alto riesgo. En México, se tiene estimado que cerca del 43% de los hombres y del 17,5% de las mujeres, todos ellos sanos y sexualmente activos tienen alguna infección por VPH. PALABRAS CLAVE: virus papiloma humano; cavidad oral; lesiones cutáneas y/o de mucosas. INTRODUCCIÓNEl virus del papiloma humano (VPH) forma parte de un grupo de virus ADN heterogéneo llamados papillomaviridae; este virus, es causante de múltiples lesiones hiperplásicas, verrucosas y papilomatosas de las células epiteliales de piel y mucosas. Tiene un tamaño aproximado de 50 nm de diámetro. Su única molécula de ADN de doble cadena, presenta aproximadamente 8,000 pares de bases. Existen más de 120 tipos de VPH, algunos tipos se muestran en la TablaI, de solo 100 se conoce su secuencia genómica completa (García-Cuellar et al., 2004). Los dos géne-ros de VPH más importantes son los papilomavirus alpha (∂) y los beta (ß), la mayoría de los virus que infectan el área genital pertenecen al género alpha (Lizano et al., 2009), según sus características clíni-cas, los VPH se pueden subdividir en cutáneos y de mucosa (Castillo, 2011 16 6 18 11 26 40 31 42 33 43 35 44 39 54 45 61 51 72 52 81 53 CP6108 56 58 59 66 68 82 Tabla I. Distintos tipos de VPH agrupados según el riesgo que representan (Muñoz et al., 2003). Alto Riesgo Bajo Riesgo

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Dermatoses of the Oral Cavity and Lips

Scully¹

2016

Rook's Textbook of Dermatology, Ninth Edition

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Oral and labial lesions are usually the result of local disease but may be the early signs of systemic disease, including dermatological disorders, and in some instances may cause the main symptoms. This chapter mainly discusses disorders of the periodontal and mucosal tissues that may be related to skin disease and that may present at a dermatology clinic. It should be borne in mind that the professionals most competent in diagnosing and treating oral diseases are those with formal dental training and who are therefore in a position to understand the full complexities of the region. This chapter is divided into a brief discussion of the biology of the mouth, an overview of the more common signs and symptoms affecting specific oral tissues, discussion of the disorders of the oral mucosa of most relevance to dermatology and a tabulated review of oral manifestations of systemic diseases. Only the more classic oral lesions are illustrated. For reasons of space restrictions, diseases affecting the teeth, salivary glands, jaws or temporomandibular joints are not discussed in any depth.

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Multifocal epithelial hyperplasia in a community in the Mayan area of Mexico

Abstract: Human papillomavirus type 13 is involved in multifocal epithelial hyperplasia among the Mexican Mayan population. The presence of HPV 13 in cells from saliva, combined with poor hygiene behaviors, may explain the familial distribution of the pathology.

Cited by 20 publications

References 21 publications

Focal Epithelial Hyperplasia Prevalence in an Endemic Population, Molecular Association of HPV-13 to Asymptomatic Patients and Comparison Between Three Elementary Schools of Different Income Levels

Focal Epithelial Hyperplasia Prevalence in an Endemic Population, Molecular Association of HPV-13 to Asymptomatic Patients and Comparison Between Three Elementary Schools of Different Income Levels

Presencia del Virus Papiloma Humano en la Cavidad Oral: Revisión y Actualización de la Literatura

Dermatoses of the Oral Cavity and Lips

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