Multi residue determination of the penicillins regulated by the European Union, in bovine, porcine and chicken muscle, by LC–MS/MS

Quechers methodologies as an alternative to solid phase extraction (SPE) for the determination and characterization of residues of cephalosporins in beef muscle using LC–MS/MS

“…Hence, any of these four cartridges could be chosen to carry out the determination of cephalosporins in muscle samples. Anyway, we finally chose Isolute ENV+ SPE cartridges because its performance demonstrated for the analysis of other antibiotics, such as penicillins and quinolones, that might occasionally occur with cephalosporins [15,[33][34][35].…”

“…In particular, LC-MS or LC/MS/MS are the preferred techniques in the determination of ␤-lactams residues. A number of authors have reported multiresidue methods for the determination of ␤-lactams in animal tissues or milk [6,[9][10][11][12][13][14][15][16][17], but only a few of these methods include some cephalosporins as targets of study [9][10][11]16,17].…”

Técnicas analíticas contemporáneas para la identificación de residuos de sulfonamidas, quinolonas y cloranfenicol

“…Acoplamiento TANDEM (MS n ): La espectrometría de masas, ya sea en modo simple MS o en tándem (MS/MS), es la técnica de detección más extendida (Dorge & Bajic 1995, Volmer et al 1997, Johnston et al 2002, Hewitt et al 2002, Thevis et al 2003, Huetos 2004, Guy et al 2007, Ramírez et al 2007, Stolker et al 2007, Ackermann et al 2008, Le Bizec et al 2009, Jin et al 2010, Macarov et al 2012. La espectrometría de masas, sin duda alguna, la técnica analítica instrumental más completa que existe actualmente.…”

Comparison of Sample Preparation and Determination of 60 Veterinary Drug Residues in Flatfish Using Liquid Chromatography-Tandem Mass Spectrometry

“…Anthelminitic drugs, such as benzimidazole, are mainly used to treat parasitic infections. β-Lactam antibiotics such as penicillin and cephalosporin are used as growth promoters and to treat bacterial infections such as respiratory or skin infections [4][5][6][7]. However, the intensive use of antibiotics in aquaculture can affect microbial populations in the aquatic environment and further promote the spread of drug-resistant bacteria and resistance genes [8,9].…”