“Muhinyo,” a disease of natives in Uganda

Bruce, David; Hamerton, A. E.; Bateman, H. R.; Mackie, F. P.

doi:10.1098/rspb.1910.0042

Cited by 6 publications

(3 citation statements)

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“…Other pathological and climatological factors, however, served to prolong disease and demographic decline in the first two decades of the twentieth century, at least in some districts of the Protectorate. Bruce noted in 1909 that ‘Muhinyo – a disease of natives in Uganda’ had ‘broken out in the province of Ankole’ (Bruce et al. 1908–1909b, ch.…”

Section: The Evolution Of a Catastrophe Sleeping Sickness In Ugandamentioning

confidence: 99%

“…The main focus of the disease, the symptoms of which included ‘fever, profuse sweating, pains in the joints and along the course of nerves, swelling of the various joints, especially the ankles and extreme weakness and emaciation’ was thought to lie along the eastern shore of Lake Edward. A particularly severe case had apparently been met with at Fort George (Katwe), although cases had also been recorded on the western shore of Lake Victoria and as far north as the Katonga River (Bruce et al. 1908–1909b).…”

Section: The Evolution Of a Catastrophe Sleeping Sickness In Ugandamentioning

confidence: 99%

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‘The gloomy forebodings of this dread disease’, climate, famine and sleeping sickness in East Africa

Endfield¹,

Ryves²,

Mills³

et al. 2009

Geographical Journal

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Identifying the nature of the association between climate, environmental, socio‐economic and political context and disease remains a major challenge, yet a better comprehension of the linkages is imperative if predictive models to guide public health responses are to be devised. Our understanding of the relationships could be improved through investigations of historical epidemics. In this paper we draw on a range of published and unpublished documents to explore the complex relationship between climate, environmental change and epidemic disease (re)emergence in East Africa, and Uganda in particular. This is a region which has experienced climate variability at a range of temporal and spatial scales, but which also has a long history of episodic epidemic disease. We focus on the late nineteenth and early twentieth centuries – a time of social, economic and political reordering in East Africa associated with European colonial intervention, but also a period which witnessed a variety of climatic, ecological and disease events. It will be argued that these developments coalesced, creating a set of spatially distinctive social and environmental conditions which fostered the emergence and prolongation of one of the most deadly episodes of disease in East African history, the sleeping sickness epidemic of c.1900–20.

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Section: The Evolution Of a Catastrophe Sleeping Sickness In Ugandamentioning

confidence: 99%

Section: The Evolution Of a Catastrophe Sleeping Sickness In Ugandamentioning

confidence: 99%

‘The gloomy forebodings of this dread disease’, climate, famine and sleeping sickness in East Africa

Endfield¹,

Ryves²,

Mills³

et al. 2009

Geographical Journal

View full text Add to dashboard Cite

show abstract

“…In 1906 Lieutenant-Colonel C Birt and Dr Strachan both reported that they had found Malta Fever to be endemic in the Orange River Colony in South Africa and that goats' milk was much used in the district (98)(99), and in 1909 they updated their report confirming the presence of a widespread epizootic of Malta fever amongst the goats of South Africa (100). Colonel Bruce, during his work in Uganda in 1909 with the Sleeping Sickness Commission, investigated the local disease 'Muhinyo', proving it to be Malta Fever (101). There were also a number of case reports from Gibraltar (102)(103), from the Orange River Colony (104), the Blue Nile (105) and Sudan (106)(107)(108).…”

Section: Epidemiologymentioning

confidence: 99%

The Corps Disease: Brucellosis and Its Historical Association with the Royal Army Medical Corps

Vassallo

1992

J R Army Med Corps

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Brucellosis (also known as Malta, Mediterranean or Undulant Fever) has aptly been nicknamed the Corps Disease because of the major role played by the Royal Army Medical Corps in elucidating its nature and discovering its mode of spread, thus leading to its prevention and eradication. This history of brucellosis, incorporating a complete bibliography of all references to the disease in the Journal of the Royal Army Medical Corps from 1903 to 1992, documents the fascinating story of this association.

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Characterization of Brucella spp. and other abortigenic pathogens from aborted tissues of cattle and goats in Rwanda

Ntivuguruzwa

Kolo

Mwikarago³

et al. 2022

Veterinary Medicine & Sci

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Background Abortions cause tremendous economic losses in food‐producing animals and may lead to food insecurity. Objectives This study aimed to characterize Brucella spp. and other abortigenic pathogens from aborted tissues of cattle. Methods For cattle, aborted tissues (n = 19) were cultured, and Brucella spp. were detected using the genus‐specific 16S‐23S ribosomal DNA interspacer region (ITS) assay and speciated using Brucella abortus, Brucella melitensis, Brucella ovis, and Brucella suis (AMOS) and Bruce‐ladder PCR assays. Brucella negative samples were screened using the eight abortigenic pathogens PCR panel. Samples from an abortion outbreak that occurred within a goat tribe were included in this investigation. Sera of females (n = 8) and males (n = 2) were analyzed using the Rose Bengal Test (RBT) and indirect enzyme‐linked immunosorbent assay (i‐ELISA), while vaginal swabs (n = 3) and aborted tissues (n = 1) were cultured and characterized. Results The ITS‐PCR detected Brucella DNA in cultures from two aborted tissues of cattle (10.5%, [2/19]), which were identified as B. melitensis (n = 1), and B. abortus (n = 1) using AMOS and Bruce‐ladder PCR assays. Campylobacter fetus (n = 7) and Leptospira spp. (n = 4) including co‐infections (n = 2) of C. fetus and Leptospira spp. were identified from the Brucella negative samples of cattle. Goats (100.0%, 10/10) were brucellosis seropositive on RBT and i‐ELISA. Mixed infections caused by B. melitensis and B. abortus were isolated from the vaginal swabs (n = 3) and aborted tissues (n = 1). Discussion and conclusions This is the first identification of abortion‐associated pathogens in aborted cattle indicating the enormous financial losses and a threat to public health. It is therefore essential to include these identified pathogens in the surveillance scheme of veterinary and human services.

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“Muhinyo,” a disease of natives in Uganda

Cited by 6 publications

References 0 publications

‘The gloomy forebodings of this dread disease’, climate, famine and sleeping sickness in East Africa

‘The gloomy forebodings of this dread disease’, climate, famine and sleeping sickness in East Africa

The Corps Disease: Brucellosis and Its Historical Association with the Royal Army Medical Corps

Characterization of Brucella spp. and other abortigenic pathogens from aborted tissues of cattle and goats in Rwanda

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