2017
DOI: 10.1016/j.nut.2017.06.006
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Molecular aspects of cancer chemopreventive and therapeutic efficacies of tea and tea polyphenols

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Cited by 79 publications
(49 citation statements)
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“…Evidence from several laboratory studies has demonstrated the strong chemopreventive and potentially cancer chemotherapeutic effects of the major green tea constituent, epigallocatechin-3-gallate (EGCG), against breast cancer (70). Most experimental data have shown that green polyphenols can modulate multiple signalling pathways and regulate the growth, survival and metastasis of cancer cell at multiple levels (71,72).…”
Section: Epigallocatechin-3-gallate (Egcg)mentioning
confidence: 99%
“…Evidence from several laboratory studies has demonstrated the strong chemopreventive and potentially cancer chemotherapeutic effects of the major green tea constituent, epigallocatechin-3-gallate (EGCG), against breast cancer (70). Most experimental data have shown that green polyphenols can modulate multiple signalling pathways and regulate the growth, survival and metastasis of cancer cell at multiple levels (71,72).…”
Section: Epigallocatechin-3-gallate (Egcg)mentioning
confidence: 99%
“…VEGF) and apoptosis (e.g. P53 , BAX , BCL2 , caspase 3; Sur & Panda, ; Yang, Du, & Yang, ). To the best of our knowledge, no direct evidence has shown that EGCG modulates WNT/JNK pathway in tumour cells.…”
Section: Discussionmentioning
confidence: 99%
“…10 Studies have shown that the polyphenols contained in insect tea inhibit gastric injury, have anti-oxidation, anti-cancer, antibacterial and anti-viral properties, lower blood sugar and blood pressure, reduce body fat and weight, and prevent cancer. [11][12][13] Tea can effectively regulate the microecology and calcium status in the digestive system, thus regulating the immunity of the body and reducing inammation. It may play a conservative role in treating inammation and avoiding surgery.…”
Section: Introductionmentioning
confidence: 99%