MgO NPs Catalyzed Eco‐friendly Reaction: A Highly Effective and Green Approach for the Multicomponent One‐pot Synthesis of Polysubstituted Pyridines using 2‐Aminobenzothiazole

Gandhi, Divyani; Agarwal, Shikha

doi:10.1002/jhet.3384

Cited by 16 publications

(10 citation statements)

References 42 publications

(34 reference statements)

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“…In this study we report the synthesis of novel bis‐coumarin derivatives using Fe 3 O 4 @sulfosalicylic acid MNPs as a novel nanocatalyst. Initially, the Fe 3 O 4 MNPs were easily prepared in water by the co‐precipitation method 43 . Then, sulfosalicylic acid catalyst was grafted onto the surface of the Fe 3 O 4 MNPs by the reaction of its carboxylic acid functional groups with hydroxyl groups on the surface of the Fe 3 O 4 MNPs in green condition (Scheme 1).…”

Section: Resultsmentioning

confidence: 99%

“…Regarding the chemistry of sustainability, the development of humanitarian, environmentally friendly, and efficient synthetic procedures for the preparation of biologically active molecules both in terms of the selection of synthetic routes and the investigation of catalyst and solvent efficiency are significant challenges in organic synthesis 34–36,40–43 …”

Section: Introductionmentioning

confidence: 99%

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A novel nanomagnetic solid acid catalyst for the synthesis of new functionalized bis‐coumarin derivatives under microwave irradiations in green conditions

Zare‐Akbari

Dastmalchi

Edjlali

et al. 2020

Applied Organom Chemis

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In this study, a novel, green, environmentally friendly and magnetically heterogeneous catalyst based on the immobilization of sulfosalicylic acid onto Fe3O4 nanoparticles (Fe3O4@sulfosalicylic acid MNPs) is reported. The bis‐coumarin analogs were synthesized in high yield using the reaction of 1 equivalent of aryl aldehydes with 2 equivalents of 4‐hydroxycoumarin in water under microwave irradiation conditions. Scanning electron microscopy, transmission electron microscopy, energy‐dispersive X‐ray spectroscopy, X‐ray diffraction, thermogravimetric analysis, dynamic light scattering, vibrating sample magnetometry, Fourier transform infrared spectroscopy, UV–visible absorption, and Brunauer‐Emmett‐Teller (BET) techniques confirmed the successful synthesis of the catalyst. The main attractive characteristics of the presented green protocol are very short reaction times (10–15 min), excellent yields, and the avoidance of hazardous or toxic reagent and solvents. Thermal durability, easy separation, and high reusability are important advantages of the new catalyst in comparison to other catalysts.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A novel nanomagnetic solid acid catalyst for the synthesis of new functionalized bis‐coumarin derivatives under microwave irradiations in green conditions

Zare‐Akbari

Dastmalchi

Edjlali

et al. 2020

Applied Organom Chemis

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“…Nanoparticles have a large surface-to-volume ratio and active coordination parts, compared to bulk materials. Nano-heterogeneous catalyst shows high activity, low energy consumption and 100% selectivity; therefore, these are suitable for the preparation of bioactive heterocyclic compounds [70,71]. Recently, magnetic nanoparticles have received great attention because of their enormous benefits such as cost-efficiency, good stability, easy separation and high surface area [72].…”

Section: Nanoparticle-catalyzed Synthesismentioning

confidence: 99%

Saturated Five-Membered Thiazolidines and Their Derivatives: From Synthesis to Biological Applications

Sahiba¹,

Sethiya²,

Soni³

et al. 2020

Top Curr Chem (Z)

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In past decades, interdisciplinary research has been of great interest for scholars. Thiazolidine motifs behave as a bridge between organic synthesis and medicinal chemistry and compel researchers to explore new drug candidates. Thiazolidine motifs are very intriguing heterocyclic five-membered moieties present in diverse natural and bioactive compounds having sulfur at the first position and nitrogen at the third position. The presence of sulfur enhances their pharmacological properties, and, therefore, they are used as vehicles in the synthesis of valuable organic combinations. They show varied biological properties viz. anticancer, anticonvulsant, antimicrobial, anti-inflammatory, neuroprotective, antioxidant activity and so on. This diversity in the biological response makes it a highly prized moiety. Based on literature studies, various synthetic approaches like multicomponent reaction, click reaction, nano-catalysis and green chemistry have been employed to improve their selectivity, purity, product yield and pharmacokinetic activity. In this review article, we have summarized systematic approaches for the synthesis of thiazolidine and its derivatives, along with their pharmacological activity, including advantages of green synthesis, atom economy, cleaner reaction profile and catalyst recovery which will help scientists to probe and stimulate the study of these scaffolds.

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“…Nanocatalysts have a high surface-to-volume ratio and active sites that display high activity and selectivity in various heterocyclic synthesis. Nanocatalysts are easily prepared, recyclable, and show clean reaction, excellent yields in short reaction time, simple separation, and reduce the use of toxic solvents and reagents [93,94]. A simple, greener, and high-yielding protocol for the preparation of perimidine derivatives from condensation of NDA and aldehydes using nano-silica sulfuric acid catalyst in EtOH at RT was developed by Mobinikhaledi et al [95].…”

Section: Nanocatalyst-assisted Synthesismentioning

confidence: 99%

Recent Advances in the Synthesis of Perimidines and their Applications

Sahiba¹,

Agarwal²

2020

Top Curr Chem (Z)

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Perimidines are versatile scaffolds and a fascinating class of N-heterocycles that have evolved significantly in recent years due to their immense applications in life sciences, medical sciences, and industrial chemistry. Their ability of molecular interaction with different proteins, complex formation with metals, and distinct behavior in various ranges of light makes them more appealing and challenging for future scientists. Various novel technologies have been developed for the selective synthesis of perimidines and their conjugated derivatives. These methods extend to the preparation of different bioactive and industrially applicable molecules. This review aims to present the most recent advancements in perimidine synthesis under varied conditions like MW radiation, ultrasound, and grinding using different catalysts such as ionic liquids, acid, metal, and nanocatalyst and also under green environments like catalyst and solvent-free synthesis. The applications of perimidine derivatives in drug discovery, polymer chemistry, photo sensors, dye industries, and catalytic activity in organic synthesis are discussed in this survey. This article is expected to be a systematic, authoritative, and critical review on the chemistry of perimidines that compiles most of the state-of-art innovation in this area.

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MgO NPs Catalyzed Eco‐friendly Reaction: A Highly Effective and Green Approach for the Multicomponent One‐pot Synthesis of Polysubstituted Pyridines using 2‐Aminobenzothiazole

Cited by 16 publications

References 42 publications

A novel nanomagnetic solid acid catalyst for the synthesis of new functionalized bis‐coumarin derivatives under microwave irradiations in green conditions

A novel nanomagnetic solid acid catalyst for the synthesis of new functionalized bis‐coumarin derivatives under microwave irradiations in green conditions

Saturated Five-Membered Thiazolidines and Their Derivatives: From Synthesis to Biological Applications

Recent Advances in the Synthesis of Perimidines and their Applications

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