Metabolomics study of dried ginger extract on serum and urine in blood stasis rats based on UPLC‐Q‐TOF/MS

Abstract

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The mechanism of ginger and its processed products in the treatment of estradiol valerate coupled with oxytocin-induced dysmenorrhea in mice via regulating the TRP ion channel-mediated ERK1/2/NF-κB signaling pathway

“…22 Ancient literature and modern studies have demonstrated the anti-inflammatory, bacteriostatic, anti-oxidant, anti-tumour, anti-blood stasis, neuropro-tective, and reproductive-system-protective effects of RZ. [23][24][25][26][27][28] Moreover, in China, a variety of processed products of RZ, such as baked ginger (BG) or ginger charcoal (GC), are used as herbal medicines to meet different clinical needs. The active ingredients responsible for the therapeutic effect of RZ include essential oils (camphene and α-zingiberene), non-volatile compounds (6-gingerol, 8-gingerol, 10-gingerol, gingerol), diphenyl heptane compounds, and other chemical constituents.…”

Metabolomics study of Angelica sinensis (Oliv.) Diels on the abnormal uterine bleeding rats by ultra‐performance liquid chromatography–quadrupole–time‐of‐flight mass spectrometry analysis

“…Metabolomics is a technique to study the metabolites and their dynamic changes before and after being stimulated or disturbed for the biological system (e.g., after a specific gene variation or environmental change). Metabolomics has been widely used in plant molecular phenotype (Showkat et al., 2019 ), drug safety (Chen et al., 2021 ; Yu et al., 2018 ), molecular pathology (Yang & Lao, 2019 ), mechanism of drug action (Su et al., 2020 ), and disease diagnosis (Karakioulaki & Stolz, 2019 ). In addition, it was also used to evaluate the impact of storage environment on food quality (Guo et al, 2019 ).…”

Role of Histological Investigation in The Protective Evaluation of Ginger

“…The use of spices in the treatment of health problems has been a tradition in the world since early ages. Su et al (8) stated that dried ginger has therapeutic effects by regulating multiple metabolic pathways. During stressful times, ginger boosts the unique defensive systems of living organisms by increasing their resistance to infections (9) .…”