Mechanical, material, and antimicrobial properties of acrylic bone cement impregnated with silver nanoparticles

Slane, Joshua; Vivanco, Juan; Rose, Warren E.; Ploeg, Heidi‐Lynn; Squire, Matthew W.

doi:10.1016/j.msec.2014.11.068

Cited by 108 publications

(84 citation statements)

References 35 publications

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“…Dental applications were obtained with composites containing silver nanoparticles that can act against S. mutans biofilm [95]. Also, bone cements modified with AgNPs significantly reduced biofilm formation on the surface of the cement [96]. Some medical devices, as well as surgical masks [97], coated with AgNPs are already in clinical trials [93] with promising results [98,99].…”

Section: Agnps Antibiofilm Activitymentioning

confidence: 99%

Silver Nanoparticles as Potential Antibacterial Agents

et al. 2015

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Multi-drug resistance is a growing problem in the treatment of infectious diseases and the widespread use of broad-spectrum antibiotics has produced antibiotic resistance for many human bacterial pathogens. Advances in nanotechnology have opened new horizons in nanomedicine, allowing the synthesis of nanoparticles that can be assembled into complex architectures. Novel studies and technologies are devoted to understanding the mechanisms of disease for the design of new drugs, but unfortunately infectious diseases continue to be a major health burden worldwide. Since ancient times, silver was known for its anti-bacterial effects and for centuries it has been used for prevention and control of disparate infections. Currently nanotechnology and nanomaterials are fully integrated in common applications and objects that we use every day. In addition, the silver nanoparticles are attracting much interest because of their potent antibacterial activity. Many studies have also shown an important activity of silver nanoparticles against bacterial biofilms. This review aims to OPEN ACCESSMolecules 2015, 20 8857 summarize the emerging efforts to address current challenges and solutions in the treatment of infectious diseases, particularly the use of nanosilver antimicrobials.

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Section: Agnps Antibiofilm Activitymentioning

confidence: 99%

Silver Nanoparticles as Potential Antibacterial Agents

et al. 2015

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“…While there is a lack of evidence on the effect AgZrPO 4 has on the physical property of the impression material, it was interesting to note that Bajrachary et al, in their study of Poly methyl methacrylate resin incorporated with silver nanoparticles did not compromise the flexural strength of the Poly methyl methacrylate resin [16]. The findings of Slane et al, in acrylic bone cement impregnated with silver nanoparticles authenticate the least effect it has on the materials physical property where it was established that under low concentrations of metallic silver nanoparticles, acrylic bone cements had retained their mechanical and material properties similar to the standard cement [17]. It may not be appropriate to say the physical properties of the impression material incorporated with AgZrPO 4 will be least affected but rather be experimented and prove accordingly.…”

Section: Discussionmentioning

confidence: 87%

Antimicrobial Property of Hydrocolloid Impression Material Incorporated with Silver Nanoparticles AgainstStaphylococcusAureus

et al. 2017

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Abstract. Dental impressions can easily become contaminated with patient's blood and saliva which are capable of transmitting infectious diseases to dental personnel. The addition of antimicrobial agents into impression materials could be effective in reducing the chances of cross-infection. Silver nanoparticles have been applied in dentistry as a potent antimicrobial agent. This study aims to evaluate the in vitro antimicrobial efficacy of silver nanoparticles incorporated to irreversible hydrocolloid impression material against Staphylococcus aureus. Silver nanoparticles (AgZrPO4, National Direct Network Company, Thailand) at concentrations of 0.25%, 0.50%, 1.00% and 1.50% w/w were added to powder of impression materials (Kromopan, Lascod, Ilaty). Impression material samples were prepared on sterile plate in accordance with manufacturer's instruction. After setting, a 100 microliter of S. aureus ATCC6538 suspension (10 6 cells/mL) were inoculated on the surface of the impression sample and left for 10 minutes. The amount of S. aureus on the surface was quantified using imprint technique on Mannitol Salt agar. Impression materials incorporated with AgZrPO4 showed antimicrobial property against S. aureus (up to 95% reduction) compared with control (impression material without AgZrPO4). Even though the mechanism of antimicrobial action was not clearly understood, AgZrPO4 incorporated to impression material was demonstrated to possess an inhibitory effect against pathogenic bacteria. Further studies are needed to investigate physical properties of the material and the clinical usage.

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“…Also, bone cements modified with NPs significantly reduced biofilm formation on the surface of the cement (96). Some medical devices, as well as surgical masks (97), coated with NPs are already in clinical trials with promising results (93,98,99).…”

Section: The Antibiofilm Activity Of Nanoparticlesmentioning

confidence: 98%

Nanomedicine opened new horizons for metal nanoparticles to treat multi-drug resistant organisms

Halawani¹

2016

Int.J.Curr.Microbiol.App.Sci

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Mechanical, material, and antimicrobial properties of acrylic bone cement impregnated with silver nanoparticles

Cited by 108 publications

References 35 publications

Silver Nanoparticles as Potential Antibacterial Agents

Silver Nanoparticles as Potential Antibacterial Agents

Antimicrobial Property of Hydrocolloid Impression Material Incorporated with Silver Nanoparticles AgainstStaphylococcusAureus

Nanomedicine opened new horizons for metal nanoparticles to treat multi-drug resistant organisms

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