Measles Epidemic Process in Various Vaccinal Periods

Цвиркун, О. В.; Тихонова, Н. Т.; Ющенко, Г. В.; Герасимова, А. Г.

doi:10.31631/2073-3046-2015-14-2-80-87

Cited by 15 publications

(4 citation statements)

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“…This trend is associated with a decrease in the level of population immunity. Although it is generally accepted that the live attenuated measles vaccine is highly effective, and especially two doses of the vaccine guarantee protection against the disease in 94.1% of cases, the intensity and duration of post-vaccination immunity may be lower compared to the level of immunity acquired after an infection with a wild-type virus, since annually 15–20% of cases fall on vaccinated and revaccinated persons, and in some years their share is up to 30% ( 6 , 7 ). When examining more than 1,000 children in Canada, it was revealed that the titer of measles antibodies in them falls by an average of 5.6%, that is, the intensity of measles immunity will be almost halved over 12 years ( 8 ).…”

Section: Introductionmentioning

confidence: 99%

Comparative Analysis of the Measles Antibody Levels in Healthy Medical Personnel of Maternity Ward and Women in Labor

et al. 2021

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It has been proven that post-vaccination immunity to measles virus after two doses of vaccine is not able to persistently protect against infection throughout life. The goal of this research was to determine the immune layer to the measles virus among women in labor and maternity ward personnel in the same medical institution. The levels of IgG antibodies to measles virus in the umbilical cord blood of 594 women in labor and 88 workers of the maternity ward were studied by ELISA. It was revealed that 22.7% of umbilical cord blood serum samples from parturient women and 21.4% of blood serum samples from maternity ward personnel were seronegative (<0.18 IU/ml). Levels of IgG antibodies to measles virus in low values (<1.0 IU/ml) were detected in 67% of blood serum samples among women in labor and 68.9% among employees of the maternity ward. Among women in labor, women under 35 years of age are at the highest risk of contracting measles; the proportion of women with low levels of protective antibodies in this age group was almost 70%, and the proportion of women without protective levels of antibodies was 23%. Compared with the age group 36–43, the age of women in labor under 35 was associated with a higher chance of not having immune protection against infection with measles virus OR [95% CI] = 2.2 [1.1–4.5] (p = 0.02) or had a low level of protection OR [95% CI] = 1.9 [1.2–3.0] (p = 0.001). It was also found that among women over 35 years of age, the proportion of persons with a high level of antibodies in women in labor was statistically significantly higher than among members of the maternity ward staff (13 and 0%, respectively, p = 0.007). Thus, maternity ward employees and women in labor constitute a risk group for measles due to the presence of a high proportion of seronegative persons among women of childbearing age (both maternity ward employees and women in labor). These conditions create the need to revise current approaches to present vaccination procedures, especially in the current epidemiological situation with COVID-19.

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Section: Introductionmentioning

confidence: 99%

Comparative Analysis of the Measles Antibody Levels in Healthy Medical Personnel of Maternity Ward and Women in Labor

et al. 2021

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“…A single measles vaccination altered some of the characteristics of the epidemic process of infection. The incidence decreased by almost 5 times in various age and social groups of the population, there was a slight increase in the inter-epidemic period and a decrease in the duration of the seasonal rise in incidence [4].…”

Section: Introductionmentioning

confidence: 89%

“…Major measles epidemics occurred every 2-3 years and resulted in more than 2.6 million deaths. The disease cyclically ranged from 50 to 1200 cases per 100,000 people per year, in one focus of the disease, on average, there were 30 cases, the proportion of foci of the disease with a prevalence of 17%, lethality involved 0.15% [2, 3,4].…”

Section: Introductionmentioning

confidence: 99%

Epidemiological features of measles infection during an outbreak in Tashkent city

Bryantseva,

Matnazarova,

Tursunova

et al. 2023

E3S Web Conf.

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The article presents the results of a retrospective analysis of the incidence of measles in the Republic of Uzbekistan for 20 years (from 2001-2020). In 2017, Uzbekistan received a WHO certificate of elimination of measles in the country, but in 2018-2019, there were large outbreaks of measles in the world. Imported cases of measles facilitated the spreading of this infection in Uzbekistan. The article describes in details the outbreak of measles that occurred during this period in Tashkent, and characterizes the epidemiological features of measles at the present stage.

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“…The epidemic situation with airborne infections regulated by specific preventive means remains tense. Cases of measles, rubella and mumps are discovered both among unvaccinated and vaccinated people 2 . Internal and external migration of global population, environmental disasters and globalization contribute to the rapid spread of viruses, outbreaks 3 .…”

Section: Introductionmentioning

confidence: 99%

The Current Epidemic Situation of Infections with Airborne Transmission of Viral Etiology in Ukraine

Podavalenko

Малыш

Zadorozhna

et al. 2022

Bangladesh J Med Sci

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Background: The infectious diseases of viral etiology with airborne transmission generally dominate in the structure of infectious incidence. Objective: To determine incidence of viral infections with airborne transmission in the north-eastern region of Ukraine, to research the impact of social and natural factors on the intensity of epidemic process. Methods: In order to determine the current epidemiological peculiarities of infections with airborne transmission in the north-eastern region of Ukraine, a retrospective and operative analysis of the incidence, reports of vaccination of decreed child population in 2009‒2019, demographic and natural indicators. Results: Trends in the incidence of influenza were characterized by chaotic nature and disorder, acute respiratory viral infections ‒ high intensity and monotony. Significant correlations were established between the incidence of influenza and number and density of the population, the incidence of acute respiratory viral infections and the coefficient of migration population movement. Direct strong correlations were found between social factors and trends in the incidence of rubella and mumps. Coronavirus infection COVID–19 has become the problem for health care facilities in Sumy oblast. Conclusion: Quantitative and qualitative characteristics of the epidemic process of infections of viral etiology with airborne transmission have changed, which requires new approaches to organization of the system of epidemiological surveillance. Bangladesh Journal of Medical Science Vol. 21 No. 03 July’22 Page: 610-619

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Measles Epidemic Process in Various Vaccinal Periods

Cited by 15 publications

References 0 publications

Comparative Analysis of the Measles Antibody Levels in Healthy Medical Personnel of Maternity Ward and Women in Labor

Comparative Analysis of the Measles Antibody Levels in Healthy Medical Personnel of Maternity Ward and Women in Labor

Epidemiological features of measles infection during an outbreak in Tashkent city

The Current Epidemic Situation of Infections with Airborne Transmission of Viral Etiology in Ukraine

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