Mean Platelet Volume in Nasal Polyps

Abstract

Reduction in MPV may be an indicator for nasal polyp formation. Further studies with a larger study population are needed to detect the possible correlation between eosinophil count and MPV values in patients with nasal polyps.

Study the relationship between nasal polyps, platelet count, mean platelet volume, neutrophil/lymphocyte ratio in patients attending otolaryngology OPD in a tertiary care teaching hospital, West Bengal

“…[28][29][30] Platelet count in the studies of Aktas et al and Sagit et al was not different between patients with nasal polyps and controls, however unlike these studies; we have observed that the platelet count was significantly lower in patients than in controls group. 8,24 A study by Ulu et al in which the platelet count was investigated in patients with septal deviation which frequently causes chronic nasal congestion reported that the platelet count was lower in patients than in controls supporting our results. 31 Increased platelet activity is associated with increased platelet volume, which can be measured by larger mean platelet volume (MPV) and platelet distribution width (PDW).…”

“…In the study by Aktas et al and Sagit et al WBC parameter was not different in patients and controls again and both of these studies are supporting our results. 8,24 "RDW" is a numerical measure of the size variability of circulating erythrocytes. 25 Disorders related to ineffective erythropoiesis or increased red blood cell destruction cause heterogeneity in size and a higher RDW.…”

“…Platelets are involved in haemostasis, tissue repairing and inflammation. 8 Although the relationship between nasal polyps and MPV was investigated in previous studies; we did not encounter any studies on the relationship between MPV, NLR and nasal polyps in Indian subjects.…”

A review of the association of mean platelet volume and red cell distribution width in inflammation

“…32,33 Afterwards, relation of decreased MPV with inflammation has been shown in different inflammatory conditions such as rheumatoid arthritis, 34 and nasal polyp. 7 In contrast, some authors reported elevated MPV in inflammatory conditions. For example, Shin et al showed that MPV increased in patients with hepatosteatosis.…”

“…Literature is full of data about the association between inflammation and RDW [1][2][3][4] and MPV. [4][5][6][7][8] Although they are both inexpensive and easy to access tests, clinical usefulness of these parameters are controversial. In this review, we aimed to show the clinical significance of these hemogram parameters in inflammatory states by reviewing the related studies in literature.…”