Manipulation of fatty acid and antioxidant profiles of the microalgae Schizochytrium sp. through flaxseed oil supplementation

Changes in phytochemical content and pharmacological activities of three Chlorella strains grown in different nitrogen conditions

“…Recently, the potential to manipulate the antioxidant activity of microalgae in response to different stimuli such as UV light (Duval et al 1999), flaxseed oil (Gaffney et al 2014), and the age of the culture and strain (Aremu et al 2014) have been documented. The current study also demonstrated that the N level in the media, harvest time, and strain type together with the interaction among these factors significantly affected the antioxidant activity in the three Chlorella strains that were investigated.…”

“…The chemical nature and the polarity of the solvents used in the extraction process determine the extraction yield and composition of the extract and thus the biological activity (Franco et al 2008). The importance of using multiple solvents has been highlighted in biological screenings of microalgae (Li et al 2007;Aremu et al 2014;Custódio et al 2014a;Gaffney et al 2014) with the resulting yields and bioactivities being largely dependent on the characteristics of the extraction solvent and the corresponding solubility of specific chemicals. This was similar in the current study with the DCM extracts having the highest activity in the DPPH assay (Fig.…”

Antioxidant activity of alcohol aqueous extracts of Crypthecodinium cohnii and Schizochytrium sp.

“…It has been reported that phenolic components may contribute to the antioxidant capacity of supplemented Schizochytrium sp. cultures (Gaffney et al, 2014), but poor correlation between TPC and the antioxidant parameters of Schizochytrium sp. was observed in this study, indicating that TPC might not be the key antioxidant component present in the alcohol aqueous extract of this species, which is consistent with a previous study (Li et al, 2007).…”

“…Lv et al (2014) explored the antioxidant activity of the microalgae oil of Schizochytrium aggregatum. Gaffney et al (2014) reported that flaxseed oil supplementation enhanced the antioxidant status of the microalgae Schizochytrium sp. However, extracts of different polarities from these two microalgae have rarely been investigated.…”

“…are two important microalgae for docosahexaenoic acid (DHA) production (Fedorova-Dahms et al, 2014;Gaffney et al, 2014). C. cohnii, distributed world-wide, is a marine heterotrophic microalga (dinoflagellate) (Beam and Himes, 1982).…”