Marine antioxidants from microalgae

Khavari, Fatemeh; Asadi, Fateme; Nouri, Fatemeh; Taheri, Mohammad; Mohammadi, Fateme; Mohammadi, Mojdeh; Habibi, Parisa; Asghari, Babak

doi:10.1016/b978-0-323-95086-2.00009-6

Cited by 2 publications

(2 citation statements)

References 138 publications

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“…on human skin keratinocytes [ 41 ]. This direction of action is probably the result of the action of lipo- and hydrophilic vitamins contained in microalgae (including α-tocopherol and ascorbic acid) as well as cooperating with each other, as well as pigments from the group of chlorophylls and carotenoids (including astaxanthin, violaxanthin and zeaxanthin), which also reveal significant antioxidant effects [ 78 , 79 , 80 ]. Water-soluble vitamin C, due to the double bond in the ring and four hydrophilic groups, has an antioxidant effect in hydrophilic environments, acting as a cofactor of enzymatic reactions as well as supporting the regeneration of vitamin E, which is involved in the protection of phospholipids [ 81 ].…”

Section: Discussionmentioning

confidence: 99%

Comparison of the Regenerative Metabolic Efficiency of Lipid Extracts from Microalgae Nannochloropsis oceanica and Chlorococcum amblystomatis on Fibroblasts

Stasiewicz,

Conde,

Domingues

et al. 2024

Antioxidants

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UVA radiation leads to oxidative stress and inflammation in skin cells. Therefore, the aim of this study was to compare the effect of lipid extracts from microalgae Nannochloropsis oceanica (N.o.) (marine) and Chlorococcum amblystomatis (C.a.) (freshwater) on the redox balance and PUFA metabolism in human skin fibroblasts modified by UVA. Lipid extracts from both types of microalgae introduced into the fibroblast medium after UVA irradiation significantly reduced the level of ROS and enhanced expression of Nrf2, which increased the activity/level of antioxidants (SOD1/2, CAT, GSH, Trx). The reduction in oxidative stress was accompanied by a decrease in the level of 4-HNE, its protein adducts and protein carbonyl groups. Microalgae also reduced the activity of COX1/2, FAAH and MAGL increased by UVA, and as a consequence, the level of lipid mediators (especially after N.o.) decreased, both from the group of endocannabinoids (AEA, 2-AG, PEA) and eicosanoids (PGE2, 15d-PGJ2, TXB2, 15-HETE), acting mainly through receptors related to G protein, the expression of which increases after UVA. This further contributed to the reduction in oxidative stress and pro-inflammatory signaling at NF-κB and TNFα levels. Therefore, it is suggested that lipid extracts from both N.o. and C.a. microalgae can be used to regenerate fibroblast metabolism disturbed by UVA radiation.

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Section: Discussionmentioning

confidence: 99%

Comparison of the Regenerative Metabolic Efficiency of Lipid Extracts from Microalgae Nannochloropsis oceanica and Chlorococcum amblystomatis on Fibroblasts

Stasiewicz,

Conde,

Domingues

et al. 2024

Antioxidants

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“…Literature has reported that phenols, transported by single electrons and hydrogen atoms, are the main source of commonly used antioxidants [21]. Marine microalgae contain a variety of polyphenols, such as green tannins, which have antioxidant properties [22].…”

Section: Introductionmentioning

confidence: 99%

Rapid Screening of Microalgae as Potential Sources of Natural Antioxidants

Wang

Pei

Xiang

et al. 2023

Foods

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In order to rapidly screen microalgae species as feedstocks for antioxidants, extracts were obtained from 16 microalgae strains (under 11 genera, 7 classes) using two methods: a one-step extraction with ethanol/water and a three-step fractionating procedure using hexane, ethylacetate, and water successively. Measuring the total phenol content (TPC), total carotenoid content (TCC), and antioxidant activity of the extracts, indicating TPC and TCC, played an important role in determining the antioxidant activity of the microalgae. A weighted scoring system was used to evaluate the antioxidant activity, and the scores of microalgal samples from two extraction methods were calculated using the same system. Among the investigated microalgae, Euglena gracilis SCSIO-46781 had the highest antioxidant score, contributing to high TPC and TCC, followed by Arthrospira platensis SCSIO-44012, Nannochloropsis sp. SCSIO-45224, Phaeodactylum tricornutum SCSIO-45120, and Nannochloropsis sp. SCSIO-45006, respectively. Additionally, the above-mentioned five strains are currently being applied in commercial production, indicating this system could be effective not only for screening microalgal antioxidants, but also for screening microalgal species/strains with strong adaptation to environmental stress, which is a critical trait for their commercial cultivation.

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Marine antioxidants from microalgae

Cited by 2 publications

References 138 publications

Comparison of the Regenerative Metabolic Efficiency of Lipid Extracts from Microalgae Nannochloropsis oceanica and Chlorococcum amblystomatis on Fibroblasts

Comparison of the Regenerative Metabolic Efficiency of Lipid Extracts from Microalgae Nannochloropsis oceanica and Chlorococcum amblystomatis on Fibroblasts

Rapid Screening of Microalgae as Potential Sources of Natural Antioxidants

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