&lt;p&gt;Enhancing ZnO-NP Antibacterial and Osteogenesis Properties in Orthopedic Applications: A Review&lt;/p&gt;

Li, Yuehong; Yang, Yue; Qing, Yun’an; Li, Ruiyan; Tang, Xiongfeng; Guo, De‐Ming; Qin, Yanguo

doi:10.2147/ijn.s262876

Cited by 52 publications

(32 citation statements)

References 150 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…reduced; but at the concentration of 10mg/mL, the antibacterial activity on S.A. is equivalent. This shows that: Increasing the concentration of ZnO/WG hybrid nanospheres, can produce the equivalent bacteriostatic effect as the ZnO nano-power, which is bene cial to the application of ZnO/WG hybrid nanospheres, as a candidate antibacterial agents, in the elds of antibacterial biomaterials, food and cosmetics preservatives, etc 28,29 .…”

Section: Analysis Of Antibacterial Test Resultsmentioning

confidence: 90%

Gliadin-mediated green preparation of Hybrid Zinc Oxide Nanospheres With Antibacterial Activity and Low Toxicity

Wang

Yao

et al. 2021

Preprint

View full text Add to dashboard Cite

The development of inorganic antibacterial agents that impart antibacterial properties to biomaterials has attracted widely attention. The paper introduced a kind of hybrid nanosphere antibacterial agent composed of wheat gliadin (WG) and zinc oxide (ZnO), with antibacterial effecacy and low toxicity. The ZnO/WG hybrid nanospheres were environment-friendly integrated by molecular self-assembly co-precipitating and freeze-drying transformating, and were characterized using X-ray diffraction (XRD), Fourier Transform infrared spectroscopy (FTIR), Scanning electron microscope (SEM), Atomic absorption spectroscopy (AAS), bacteriostasis test and safety evaluation. It was found that the prepared hybrid nanospheres were composed of two components, ZnO and wheat gliadin, with a diameter scope of 100~200 nm. The content of ZnO in the hybrid nanospheres can reach 46.9~70.2% (w/w); The anti-bacteria tests proved that the prepared ZnO/WG nanospheres (containing 70% ZnO) have an significant inhibitory effect on E. coli (E.C.) and Staphylococcus aureus(S.A.) while the suspension concentration of the nanospheres was above 5 mg/mL. Furthermore, the ZnO/WG nanospheres are relatively safe and highly effective in cells and mice. Therefore, the prepared novel ZnO/WG hybrid nanospheres were supposed to apply in the preparation of anti-infective wound dressings, tissue engineering skin scaffold materials, food and cosmetics preservatives, and so on.

show abstract

Section: Analysis Of Antibacterial Test Resultsmentioning

confidence: 90%

Gliadin-mediated green preparation of Hybrid Zinc Oxide Nanospheres With Antibacterial Activity and Low Toxicity

Wang

Yao

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…Besides, compared with ZnO nano-powder, at the low concentration, 2 mg/mL and 5 mg/mL, the bacteriostatic effect of ZnO/WG hybrid nanospheres on E. coli reduced; but at the concentration of 10 mg/mL, the antibacterial activity on S. aureus is equivalent. This shows that: Increasing the concentration of ZnO/WG hybrid nanospheres, can produce the equivalent bacteriostatic effect as the ZnO nano-power, which is beneficial to the application of ZnO/WG hybrid nanospheres, as a candidate antibacterial agents, in the fields of antibacterial biomaterials, food, and cosmetics preservatives, etc 35 , 36 .…”

Section: Resultsmentioning

confidence: 93%

Gliadin-mediated green preparation of hybrid zinc oxide nanospheres with antibacterial activity and low toxicity

Wang

Yao

et al. 2021

Sci Rep

View full text Add to dashboard Cite

The development of inorganic antibacterial agents that impart antibacterial properties to biomaterials has attracted wide attention. The paper introduced a kind of hybrid nanosphere antibacterial agent composed of wheat gliadin (WG) and zinc oxide (ZnO), with antibacterial efficacy and low toxicity. The ZnO/WG hybrid nanospheres were environment-friendly integrated by molecular self-assembly co-precipitating and freeze-drying transformation, and were characterized using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscope (SEM), atomic absorption spectroscopy (AAS), specific surface and pore size analysis, bacteriostasis test, reactive oxygen species (ROS) determination and safety evaluation. It was found that the prepared hybrid nanospheres were composed of two components, WG and ZnO, with a diameter scope of 100–200 nm; the content of ZnO in the hybrid nanospheres can reach 46.9–70.2% (w/w); the bacteriostasis tests proved that the prepared ZnO/WG nanospheres generating ROS, have a significant inhibitory effect on E. coli and S. aureus; furthermore, the ZnO/WG nanospheres are relatively safe and highly biocompatible in cells and mice. Therefore, the prepared novel ZnO/WG hybrid nanospheres were supposed to apply in the preparation of anti-infective wound dressings, tissue engineering skin scaffold materials, food, and cosmetics preservatives, and so on.

show abstract

“…Further, the study revealed that the gold nanobiomaterial improved the cell viability of MG-63 cell lines with strong antinociperceptive activity, which is beneficial for dental pain management applications during tissue implantation (Wang and Wang, 2020). Moreover, plant synthesized zinc oxide nanoparticles has also been proposed to be a potential nanobiomaterial with in vitro osteogenic activity and antibacterial property for dental implant applications (Li Y. et al, 2020). Moreover, silver nanoparticles synthesized via white pepper oleoresin (Paul et al, 2020), Oleo europaea extract (Umai et al, 2020), clove and cinnamon extracts synthesized with zinc oxide nanoparticles (Mohapatra et al, 2020), exhibited enhanced antimicrobial activities against oral pathogens.…”

Section: Plant-derived Nanobiomaterials As Dental Implantsmentioning

confidence: 98%

Plant-Derived Nanobiomaterials as a Potential Next Generation Dental Implant Surface Modifier

2021

View full text Add to dashboard Cite

Dental implants resemble synthetic materials, mainly designed as teeth-mimics to replace the damaged or irregular teeth. Specifically, they are demarcated as a surgical fixture of artificial implant materials, which are placed into the jawbone, and are allowed to be fused with the bone, similar to natural teeth. Dental implants may be categorized into endosteal, subperiosteal, and zygomatic classes, based on the placement of the implant “in the bone” or on top of the jawbone, under the gum tissue. In general, titanium and its alloys have found everyday applications as common, successful dental implant materials. However, these materials may also undergo corrosion and wear, which can lead to degradation into their ionic states, deposition in the surrounding tissues, as well as inflammation. Consequently, nanomaterials are recently introduced as a potential alternative to replace the conventional titanium-based dental implants. However, nanomaterials synthesized via physical and chemical approaches are either costly, non/less biocompatible, or toxic to the bone cells. Hence, biosynthesized nanomaterials, or bionanomaterials, are proposed in recent studies as potential non-toxic dental implant candidates. Further, nanobiomaterials with plant origins, such as nanocelluloses, nanometals, nanopolymers, and nanocarbon materials, are identified to possess enhanced biocompatibility, bioavailability and no/less cytotoxicity with antimicrobial efficacy at low costs and ease of fabrication. In this minireview, we present an outline of recent nanobiomaterials that are extensively investigated for dental implant applications. Additionally, we discuss their action mechanisms, applicability, and significance as dental implants, shortcomings, and future perspectives.

show abstract

<p>Enhancing ZnO-NP Antibacterial and Osteogenesis Properties in Orthopedic Applications: A Review</p>

Cited by 52 publications

References 150 publications

Gliadin-mediated green preparation of Hybrid Zinc Oxide Nanospheres With Antibacterial Activity and Low Toxicity

Gliadin-mediated green preparation of Hybrid Zinc Oxide Nanospheres With Antibacterial Activity and Low Toxicity

Gliadin-mediated green preparation of hybrid zinc oxide nanospheres with antibacterial activity and low toxicity

Plant-Derived Nanobiomaterials as a Potential Next Generation Dental Implant Surface Modifier

Contact Info

Product

Resources

About