2021
DOI: 10.1136/bmjopen-2020-042053
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Long-term trends and regional variations of hypertension incidence in China: a prospective cohort study from the China Health and Nutrition Survey, 1991–2015

Abstract: ObjectiveThe aim is to explore the trends of hypertension incidence and regional variations in China from 1991 to 2015.DesignA dynamic prospective cohort study.SettingChina Health and Nutrition Survey 1991–2015.Participants12 952 Chinese adults aged 18+ years.Primary outcome measuresIncident hypertension from 1993 to 2015.ResultsAge-standardised hypertension incidence increased from 40.8 per 1000 person-years (95% CI 38.3 to 43.4) between 1993 and 1997 to 48.6 (95% CI 46.1 to 51.0) between 2011 and 2015. The i… Show more

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Cited by 14 publications
(12 citation statements)
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References 48 publications
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“…Obese individuals have a higher likelihood of developing HTN, and the mechanisms behind this relationship are complex and involve various physiological processes such as sympathetic nervous system activation, renin-angiotensin-aldosterone system stimulation, changes in adipose-derived cytokines, insulin resistance, and renal structural and functional alterations. (23,(42)(43)(44). While the incidence of HTN is typically higher in men than in women, the ndings of this study suggest that the opposite is true.…”
Section: The Association Between the Demographic And Lifestyle Variab...mentioning
confidence: 48%
See 1 more Smart Citation
“…Obese individuals have a higher likelihood of developing HTN, and the mechanisms behind this relationship are complex and involve various physiological processes such as sympathetic nervous system activation, renin-angiotensin-aldosterone system stimulation, changes in adipose-derived cytokines, insulin resistance, and renal structural and functional alterations. (23,(42)(43)(44). While the incidence of HTN is typically higher in men than in women, the ndings of this study suggest that the opposite is true.…”
Section: The Association Between the Demographic And Lifestyle Variab...mentioning
confidence: 48%
“…Although previous research has identi ed several risk factors for HTN, including age, low physical activity, smoking, unhealthy eating habits (such as high salt consumption), race, and alcohol consumption, con icting ndings have arisen due to limitations in study design, analysis, and the number of factors considered. (18)(19)(20)(21)(22)(23). Speci cally, regular logistic regression, which is commonly used to examine risk factors for HTN, may produce biased estimates when dealing with rare events (those with less than 10% occurrence) or an unbalanced number of independent variables.…”
Section: Introductionmentioning
confidence: 99%
“…Our results showed that the prevalence of hypertension in Tianjin in 2018 was much higher than the national level (23.2%, from 2012 to 2015). [ 2 ] Previous studies have shown that the higher incidence and prevalence of hypertension in northeastern and eastern China compared to western China [ 2 , 9 ] may be closely associated with higher salt intake, obesity rates and higher body weight. In 2017, high sodium intake was the leading dietary risk for deaths and high DALYs in China.…”
Section: Discussionmentioning
confidence: 99%
“…[8] The CHNS study, with a prospective cohort of 12,952 Chinese adults aged >18 years, showed that the agestandardized prevalence of hypertension increased from 40.8/1000 person-years in 1993-1997 to 48.6/1000 person-years in 2011-2015. [9] The awareness, treatment, and control rates of hypertension were rising among Chinese adults aged ≥18 years, at 51.6%, 45.8%, and 16.8%, respectively in 2015.…”
Section: Hypertensionmentioning
confidence: 99%