Long-term exposure to jet fuel: an investigation on occupationally exposed workers with special reference to the nervous system.

Irreversible effects of trichloroethylene exposure on the central nervous system.

“…In general such symptoms have been reported to disappear when the subject is removed from exposure. There is increasing evidence of a connection between long-term exposure to moderate concentrations of volatile solvents and chronic damage to the CNS (1,10). Thus, although there is no firm experimental support, there is reason to believe that TCE might alone -or even more probably in combination with other solvents -cause permanent damage to the CNS, if the time of exposure is long enough.…”

Short-Term Pulmonary Response to Inhaled JP-8 Jet Fuel Aerosol in Mice

“…Liver studies in rats and mice were characterized by alterations in serum biomarkers, but there was a lack of histopathologic correlation following whole-body inhalation exposure (10,11,12). Human neurological effects were characterized by acute symptoms of dizziness, headache, nausea, and fatigue; chronic symptoms were predominately neurasthenic effects of depression, lack of initiative, and memory impairment (8). In contrast to the vapor-only studies, 7-day subchronic exposures to aerosolized JP-8 in rats resulted in perivascular and interstitial edema, which were accompanied by leukocytic infiltration and morphological alterations to the distal lung (6).…”

Exposure to organic solvents. A cross-sectional epidemiologic investigation on occupationally exposed care and industrial spray painters with special reference to the nervous system.

“…Around 1975 the first results from epidemiologic studies on solvent-exposed workers were published in Finland and Sweden. In investigations on industrial workers (52), house painters (9,39), car painters (38,75), and jet fuel-exposed workers (44,45), the results indicated effects on the central and peripheral nervous systems as a result of long-term but relatively low exposure to different organic solvents. When the present study was initiated, the preliminary results of the epidemiologic studies had attracted great attention from both the general public and scientists, and uncertainty reigned as to whether or not the permitted limits could be regarded as adequate.…”