“…While 2 studies investigated associations between baseline WMH volume and change in either subregional 15 or global 37 CBF, one study considered associations between change in WMH volume and change in cortical grey matter CBF. 36 Fifteen studies used ASL 6-8, 10, 14, 15, 19, 20, 25, 27, 30, 32, 34-36 , 3 used CT perfusion 18,28,29 , 2 used dynamic susceptibility contrast (DSC) MRI 9,37 , one study each used SPECT 21 , phase contrast MRI 22 , CT angiography/digital subtraction angiography, 31 PET, 23 and a combination of CT and DSC MRI 12 . Five studies used transcranial Doppler ultrasound 16,17,24,26,33 .…”