2010
DOI: 10.1111/j.1442-200x.2009.02893.x
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Lead exposure and its association with pubertal development in school‐age Egyptian children: Pilot study

Abstract: These findings consolidate the cumulative medical evidence of the deleterious effect of high lead levels on pubertal development, possibly through the hypothalamic-pituitary-gonadal axis.

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Cited by 22 publications
(9 citation statements)
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“…2 Fetuses may remain vulnerable, even if the mother's exposure ceased years earlier, because lead can accumulate in mothers for extended periods of time. [12][13][14] Elevated lead levels were also associated with loss of motor abilities and poor scholastic achievement in children. Lead was found to deteriorate cognition and impair puberty.…”
mentioning
confidence: 99%
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“…2 Fetuses may remain vulnerable, even if the mother's exposure ceased years earlier, because lead can accumulate in mothers for extended periods of time. [12][13][14] Elevated lead levels were also associated with loss of motor abilities and poor scholastic achievement in children. Lead was found to deteriorate cognition and impair puberty.…”
mentioning
confidence: 99%
“…Lead was found to deteriorate cognition and impair puberty. [12][13][14] Elevated lead levels were also associated with loss of motor abilities and poor scholastic achievement in children. 13 In 1989, the World Health Organization (WHO) conducted a multicentered study in different countries and quantified lead levels in breast milk.…”
mentioning
confidence: 99%
“…FSH and LH were significantly reduced in children of both sexes, and testosterone levels were reduced in boys with high lead. [ 26 ] Recently, Minguez-Alarcon et al . examined the association between peripubertal BLLs and semen quality in young adulthood.…”
Section: R Esults and Discussionmentioning
confidence: 99%
“…Studies have found a link between higher lead levels and hypertension, renal failure, and depression [2,20,21]. Other studies have also found significant associations between elevated lead levels and hematic, renal, gastrointestinal, mental, cognitive, and developmental impairments [22][23][24]. Moreover, children exposed to lead were also shown to report poor academic and scholastic achievements [22][23][24].…”
Section: Introductionmentioning
confidence: 99%