Laser induced fluorescence model of human goiter

Abstract

Laser induced fluorescence (LIF) with wide area surveillance for resected thyroid tissue solid chunks is presented. The characteristic LIF spectra of goiter were established. The state of tissue at each point represents a superposition of normal and pathology states. To our knowledge two co-existing pathological effects were observed optically for the first time. It is demonstrated that the LIF spectral functions and their intensities well-labeled such areas and represent a good tool for medical diagnostics of goiter and for the definition of the degree of abnormality and geometrical sizes of these areas. LIF spectra from different points of a thyroid tissue solid chunk

Study of vitamin A distribution in rats by laser induced fluorescence spectroscopy

“…2 presents the LIF spectra of ileum and liver tissues obtained from control According to our model they represent the B-type molecules. It is well known that if an excitation wavelength of 337 nm is used, then collagen display their fluorescence peaks at approximately 390 nm, and NADH at 470 nm (see for example [11] and the references cited there). Hence, it is evident that, in spite of difference in LIF spectra, in the both kinds of tissue dominate the fluorescence of coenzyme NADH with maximum around 470 nm.…”

“…About 2000 measurements were made per spot per sample in these experiments. The temperature increment in the scanning mode did not affect the spectral measurements [11].…”

“…Laser induced fluorescence spectroscopy (LIFS) and imaging is used intensively for different biochemical and medical applications [8][9][10][11]. For our knowledge, no attempts were made to use LIFS in study of formation of lipid droplets until now.…”

Laser-induced fluorescence of oral mucosa cancer

“…About 2 × 10 3 measurements were made per spot per sample in these experiments. The temper ature increment in the scanning mode did not affect the spectral measurements [5].…”

Laser Induced Fluorescence Studies of Blood Plasma and Tumor Tissue of Men with Prostate Tumors

“…Emission spectra recorded from 300 to 600 nm were displayed on a PC monitor and stored as data files. About 2,000 measurements were made per spot per sample in these experiments [8] [9].…”