Lab on a Chip for the Colorimetric Determination of Nitrite in Processed Meat Products in the Jordanian Market

Abstract

Nitrite and Nitrate have been used extensively as additives in various meat products to enhance flavor, color, and to preserve the meat from the bacterial growth. High concentrations of nitrite can threat human health since several studies in the literature claim that nitrite is associated with cancer incidences, leukemia, and brain tumors. Therefore, it is vital to measure the nitrite concentrations in processed meat products. In this study, an in-lab miniaturized photometric detection system is fabricated to inspect the nitrite concentration in processed meat products in Jordan. The analytical performance of nitrite detection is evaluated based on three key statistical parameters; linearity, limit of detection, and limit of quantitation. Respectively, for the fabricated system, the three values are found to be equal to 0.995, 1.24 × 10−2 ppm, and 4.12 × 10−2 ppm. Adherence to Beer’s law is found over the investigated range from 2.63 ppm to 96.0 ppm. The developed system is utilized for photometric detection of nitrite in processed meat products available in the Jordanian market like pastrami, salami, and corned beef. In all of the analyzed samples, the nitrite content is found to be lower than 150 ppm, which represents the maximum allowable nitrite limit.

Advances in Computational Fluid Mechanics in Cellular Flow Manipulation: A Review

“…Microfluidics chips offer new approaches for cell assays and have also been used for studying of cell biology by providing platforms for manipulating, separating, sorting, filtering, trapping, and detecting tiny biological particles based on cellular heterogeneity. They can simulate small-scale fluid flow and chemical gradients and offer full manual control over the particles to study the desired details, e.g., for food market, clinical, pharmaceutical, and other applications [1][2][3][4][5][6][7]. Precise manipulations such as focusing, separation, and fractionation of cells is a vital capability of microfluidics which can be achieved by engineering hydrodynamics forces based on unique physical attributes of cells such as size [8,9], density [9,10], deformability [11][12][13], and morphology [14] using variety of methods such as crossflow filtration [15], electrode arrays [16], optical force switching [17] and other methods, some of and other methods, some of which can be found in detail in the review presented in [18].…”

Monolithic Integrated OLED–OPD Unit for Point-of-Need Nitrite Sensing

“…Colorimetric nitrite sensors mostly use LEDs as the light source. Devices such as CCD cameras, spectrometers, smartphone cameras, photomultiplier tubes (PMT) and photodiodes (PD) were recently successfully integrated on the detector side [13][14][15][16][17][18][19][20][21][22]. While very impressive results are achieved with the compact integration of the inorganic optoelectronic devices and microfluidic-based approaches, these systems are still rather bulky.…”

Rapid Inkjet-Printed Miniaturized Interdigitated Electrodes for Electrochemical Sensing of Nitrite and Taste Stimuli

“…IDEs have been employed for the detection of various components and contaminants in water, including salinity and ions [ 24 , 33 ]. Nitrite is also a contaminant found in water obtained from unchecked sources which, when consumed in excess via contaminated water sources, can have adverse effects on humans [ 34 , 35 ]. In this context, nitrite detection has been demonstrated as a possible application for fabricated IDEs in this work.…”