Recently, remarkable developments have taken place, leading to significant improvements in microfluidic methods to capture subtle biological effects down to single cells. As microfluidic devices are getting sophisticated, design optimization through experimentations is becoming more challenging. As a result, numerical simulations have contributed to this trend by offering a better understanding of cellular microenvironments hydrodynamics and optimizing the functionality of the current/emerging designs. The need for new marketable designs with advantageous hydrodynamics invokes easier access to efficient as well as time-conservative numerical simulations to provide screening over cellular microenvironments, and to emulate physiological conditions with high accuracy. Therefore, an excerpt overview on how each numerical methodology and associated handling software works, and how they differ in handling underlying hydrodynamic of lab-on-chip microfluidic is crucial. These numerical means rely on molecular and continuum levels of numerical simulations. The current review aims to serve as a guideline for researchers in this area by presenting a comprehensive characterization of various relevant simulation techniques.
In this study, we evaluated the fundamental physical behavior during droplet formation and flow from a rotary bell spray in the absence of an electrostatic field. The impact of a wide range of operating parameters of the rotary bell sprayer, such as flow rates, rotational speeds, and spatial positioning, on droplet sizes and size distributions using a three-dimensional (3-D) mapping was studied. The results showed that increasing the rotational speed caused the Sauter mean diameter of the droplets to decrease while increasing flow rate increased the droplet sizes. The rotational speed effect, however, was dominant compared to the effect of flow rate. An increase in droplet size radially away from the cup was noted in the vicinity of the cup, nevertheless, as the lateral distances from the cup and rotational speed were increased, the droplet sizes within the flow field became more uniform. This result is of importance for painting industries, which are looking for optimal target distances for uniform painting appearance. Furthermore, the theoretical formulation was validated with experimental data, which provides a wider range of applicability in terms of environment and parameters that could be tested. This work also provides an abundance of measurements, which can serve as a database for the validation of future droplet disintegration simulations.
In this paper, transverse vibration analysis of rotating micro-beam is investigated based on the modified couple stress theory. The simply-supported micro-beam is modeled utilizing Euler-Bernoulli and Timoshenko beam theories. The system is rotating around a fixed axis perpendicular to the axial direction of the beam. For the first time, displacement filed is introduced as a coupled field to the translational field. In other words, the mentioned rotational displacement field is expressed as a proportional function of translational displacement field using first (axial), second (lateral), and third (angular or rotational) velocity factors. Utilizing Hamilton’s approach as a variational method, dynamic-vibration equations of motion of the proposed model are derived. Galerkin’s method is adopted to solve the equation corresponding to the Euler–Bernoulli and Timoshenko beams. For the case considering shear deformation effects, Navier method is chosen. For evaluation of current results and models, they are compared with those available at the benchmark. In this paper; effects of slenderness ratio, axial, lateral, and angular velocity factors, and rotations of the beam on the frequency are reported. Based on the results presented, mentioned factors should be counted in the analysis and design of such rotating micro-systems.
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