Juvenile periodontitis Localization of bone loss in relation to age, sex, and teeth

Abstract

The distribution of bone loss in 156 patients, 12-32 years old, with juvenile periodontitis was analyzed according to age, sex, and teeth affected. The criteria for bone loss were: vertical or horizontal bone loss involving more than one-third of the root as judged by radiographs. Three age groups were established: 12-18, 19-25, and 26-32 years old. Three types of bone loss localization were defined: I. First molars and/or incisors. II. First molars, incisors and some additional teeth (total less than 14 teeth). III. General involvement . There was a dominance of female patients. The ratio females: males decreased from 5.3:1 in the youngest age group to 1.5:1 in the oldest. The mean number of involved teeth increased with age from 5.3 teeth in the youngest group to 11.6 in the oldest. The frequency of type I bone loss decreased from 55% in the youngest group to 7% in the oldest. Type II occurred with the same frequency (55-58%) in all three age groups. Type III was not seen in the youngest group whereas it increased from 17% in the middle to 35% in the oldest group. Of the total number of involved teeth, the first molars were most frequently affected, followed by the incisors. Maxillary teeth were involved to a slightly higher degree than mandibular teeth, and there was a strong "mirror effect" between involved teeth of right and left jaw halves.

Early onset periodontitis: A comparison and evaluation of two proposed modes of inheritance

“…Autosomal recessive (AR) and X-linked dominant (XD) transmission with partial penetrance are two hypotheses currently favored in the dental literature [Fourel, 1972;Jorgenson et al, 1975;Melnick et al, 1976;SaxCn, 1980b;SaxCn and Nevanlinna, 1984;Vandesteen et al, 19841. It is perhaps not surprising that no clear consensus as to the genetic mechanism has emerged, in view of (1) variation in expression and age of onset of the trait; (2) it's low population prevalence, and sex specific incidence; (3) the inherent difficulties involved in formally rejecting either hypothesis by analysis of sibships data; and (4) the difficulties involved in obtaining multigenerational data and adequate sample sizes.…”

Inhibition of fibroblast proliferation and collagen synthesis by capsular material from Actinobacillus actinomycetemcomitans

“…Bacterial products can exert a direct effect or can act indirectly by inducing inflammatory changes. In localised juvenile periodontitis (LJP) there is marked tissue destruction, especially bone resorption, but minimal inflammation (Baer, 1971;Hsrmand and Frandsen, 1979), and the direct cytotoxic effects of bacterial products appear to play an important role. Such effects on the fibroblasts of the periodontium result in a decrease in cell numbers and a net loss of collagen (Page and Schroeder, 1976).…”

Prevalence and characteristics of aggressive periodontitis

“…However, there are patients who experienced disease progression until tooth loss occurs despite a non-adequate conventional treatment has been done. 3,20,21 Table 2 also illustrates a systemic disease, smoking, hormonal changes in women, and the consumption of certain drugs. It is important to note when determining diagnosis, prognosis, and selection of appropriate therapy.…”