Itching following burns: epidemiology and predictors

Loey, Nancy E. Van; Bremer, M.; Faber, A.W.; Middelkoop, Esther; Nieuwenhuis, M.K.

doi:10.1111/j.1365-2133.2007.08278.x

Cited by 85 publications

(127 citation statements)

References 29 publications

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“…It can result in severe functional and cosmetic impairment, and symptoms of pruritus and pain, which are responsible for a decrease in quality of life (Atkinson et al, 2005;Bock et al, 2006;Van Loey et al, 2008). The abnormal biological behavior of fibroblasts plays a central role in hypertrophic scar formation and development, which can change into myofibroblasts and facilitate both collagen deposition and wound contraction (Tuan & Nichter, 1998).…”

Section: Discussionmentioning

confidence: 99%

Essential oil from rhizomes ofLigusticum chuanxionginduces apoptosis in hypertrophic scar fibroblasts

Zhang

et al. 2010

Pharmaceutical Biology

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Section: Discussionmentioning

confidence: 99%

Essential oil from rhizomes ofLigusticum chuanxionginduces apoptosis in hypertrophic scar fibroblasts

Zhang

et al. 2010

Pharmaceutical Biology

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“…Therefore, hypertrophic scars are indurate, elevated, poorly extensible and also characterized by hypervascularity, thereby providing their erythematous appearances (Alster and West, 1997;Scott et al, 2007;Van Loey et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

Efficacy of the combination of herbal extracts and a silicone derivative in the treatment of hypertrophic scar formation after burn injury

Muangman¹,

Aramwit

Palapinyo³

et al. 2011

Afr. J. Pharm. Pharmacol.

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The development of hypertrophic scars is an unsolved problem in the process of wound healing. The objective of this research was to study the efficacy of the combination of herbal extracts and a silicone derivative in a gel preparation (Cybele ® Scagel) on the treatment of deep second degree burns after complete epithelialization. Sixty-three patients were enrolled in this study. One wound area larger than 10 × 10 cm was selected from each patient to receive treatment with Cybele ® Scagel. Patients were observed for pigmentation, pliability, pain and itching for 0, 2, 4, 8, 12, 16, 20 and 24 weeks after treatment. Their data and wound characteristics were collected during each visit using the Vancouver scar scale. After 24 weeks, all scales (pigmentation, pliability, pain and itching) were significantly lower in the sites treated with Cybele ® Scagel compared with the previous time points (p< 0.05). However, vascularity and height scale were not significantly different (p> 0.05). One patient was excluded at week 2 because of moderate itching at the wound site, which could have interfered with the evaluation. The application of Cybele ® Scagel might have some beneficial effects for prevention of hypertrophic scar formation after partial thickness burn injuries.

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“…As the degree of the burn increases, the texture of the scar becomes more visible (5,22). In our study, it was determined that OSAS scores increased significantly as the burn grade increased (p<0.05).…”

Section: Discussionmentioning

confidence: 64%

Reliability and Validity of the Turkish Version of Patient and Observer Scar Assessment Scale in Patients with Burns

Aydoğan¹,

Kabuk²,

Kazan³

2017

tdd

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ÖzAmaç: Hasta ve Gözlemci Skar Değerlendirme Ölçeği'nin (HGSDÖ) Türkçe formunun yanık hastalarında geçerlik ve güvenirliğini değerlendirmek amacıyla yapılmıştır. Yöntemler: Metodolojik tipte bir çalışmadır. Çalışmanın verileri HGSDÖ, anket formu ve pleksiglas kullanılarak toplanmıştır. Hasta Skar Değerlendirme Ölçeği (HSDÖ) hastalar tarafından (n=53), Gözlemci Skar Değerlendirme Ölçeği (GSDÖ) birbirinden bağımsız iki gözlemci tarafından doldurulmuştur. İki hafta sonra ölçekler 25 hastaya tekrar uygulanmıştır. Veriler Kruskal-Wallis ve Mann-Whitney U testi ile analiz edilmiştir. Ölçeğin kapsam geçerliğinde Kaiser-Meyer-Olkin ve Barlett testi, yapı geçerliğinde Açıklayıcı Faktör Analizi (AFA) ve Doğrulayıcı Faktör Analizi (DFA), güvenirliğin değerlendirilmesinde iç tutarlılık, Cronbach's alpha ve intraclass correlation coefficient (ICC) ile bakılmıştır. HGSDÖ'de yer alan 7. madde, orijinal ölçekte olduğu gibi, ölçeğin puanı dışında tutularak değerlendirilmiştir. Bulgular: AFA'ya göre ölçeğin faktör yüklerinin uygun aralıkta, DFA'ya göre orijinal ölçeğin 6 madde tek faktörlü yapısının geçerli ve uyum indekslerinin yüksek, ölçeğin toplam puanı ile 7. madde arasında ICC'nin doğru orantılı, iç tutarlılığın yüksek derecede güvenilir (HSDÖ α=0,992, GSDÖ α=0,993), gözlemciler arasında tutarlılığın yüksek (α=0,952, r=0,909) olduğu saptanmıştır. Hastaların yanıklarının derecesi arttığında, GSDÖ puanının anlamlı derecede arttığı belirlenmiştir (p<0,05). Sonuç: HGSDÖ'nün Türk toplumu için yanık hastalarında geçerli ve güvenilir bir ölçek olduğu belirlenmiştir. Anahtar kelimeler: Yanık, skar, ölçek, güvenirlik ve geçerlik, hasta, gözlemci Objective: To evaluation reliability and validity of the Turkish version of Patient and Observer Scar Assessment Scale (POSAS) in patients with burns. Methods: This is a methodologically study. Data were collected using POSAS, survey form and plexiglas. Patient Scar Assessment Scale (PSAS) was completed by patients (n=53) and Observer Scar Assessment Scale (OSAS) was completed by two observers separately. The test-retest was measured applying the scales in 25 patients after two weeks. Data were analyzed by Kruskal-Wallis and Mann-Whitney U test. Content validity was determined using Kaiser-Meyer-Olkin, Barlett's test and structure validity was performed by explanatory factor analysis (EFA) and confirmatory factor analysis (CFA); reliability was evaluated using internal consistency, Cronbach's alpha and intraclass correlation coefficient (ICC). Results: Factor weights were in appropriate range according to EFA, 6 items single factor structure of the original scale was valid and had high consistency index according to CFA, ICC between the 7 th item and the total points was proportional, inner consistency was highly reliable (PSAS α=0.992, OSAS α=0.993), consistency between the observers was high (α=0.952, r=0.909). It was determined OSAS scores increased as the burn degree increased (p<0.05). Conclusion: POSAS was determined to be a valid and reliable scale in patients with burns in t...

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Itching following burns: epidemiology and predictors

Abstract: Itching remains a significant problem over a 2-year period. Individuals having undergone surgical procedures and experiencing early post-traumatic distress are more likely to suffer from long-term and persistent itching. Implications regarding practice and research are discussed.

Cited by 85 publications

References 29 publications

Essential oil from rhizomes ofLigusticum chuanxionginduces apoptosis in hypertrophic scar fibroblasts

Essential oil from rhizomes ofLigusticum chuanxionginduces apoptosis in hypertrophic scar fibroblasts

Efficacy of the combination of herbal extracts and a silicone derivative in the treatment of hypertrophic scar formation after burn injury

Reliability and Validity of the Turkish Version of Patient and Observer Scar Assessment Scale in Patients with Burns

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