Investigation of Production Process and GC-MS Analysis of Chemical Constituents of Three Traditional Medicines Sumbawa Oils

Abstract

The aims of this research are to study the production process and the chemical composition of three traditional Sumbawa oils from Benete Village (BT), Batu Dulang Village (BD), and Hutan Sumbawa (HS). A survey was conducted to learn the production process; and the chemical composition of the Sumbawa oils was determined by fractionation method using three solvents with different polarity (methanol, dichloromethane (DCM) and nhexane), followed by GC-MS analysis of each extract. In general, the three Sumbawa Oils were traditionally produced by mixing various species of medical plants into the coconut oil through heating process. Based on GC-MS analysis, the constituents of the Sumbawa oils are mainly fatty acid, fatty acid ester, monoterpene, and sesquiterpene. Three major identical compounds were identified in all three products with different percentages of abundance namely octadecanoic acid/stearic acid, hexadecanoic acid/palmitic acid, and methyl palmitate. Furthermore, there were other major compounds such as linoleic acid, lycopersene, and dodecanoic acid/lauric acid. The non-natural product compounds found in Sumbawa oil extracts and the biological activities of major compounds are discussed in this article.

Lycopersene: A review on extraction, identification and purification and applications

“…The plant species of Teucrium polium was extracted by water with solvent (150 g: 1500 ml), 4°C/3 h in Clevenger apparatus (Ebadollahi et al, 2015; Ebadollahi & Taghinezhad, 2020). The local made herbal oil was extracted using methanol, dichloromethane; hexane (3 × 100 ml) by Hadi et al (2018), and its extract was concentrated in rotary evaporator. Hurtado‐Díaz et al (2019) used hexane; dichloromethane, water: methanol solvent utilized to extract the plant samples Tournefortia hirsutissima (480 g/4 × 200 ml/24 h) and concentrated contains yield of 1.50%; 0.63%; 4.08%.…”

“…The leaves of Leea indica (Bandicoot berry) belonging to the family Vitaceae were gathered and examined (Ebadollahi & Taghinezhad, 2020;Hadi et al, 2018;Hurtado-Díaz et al, 2019)…”

“…Palm oil belonging to the family of Arecaceae was collected and examined in Pekanbaru, Indonesia (Setianingsih & Bahri, 2017). Similarly, the Sumbawa oil was collected and examined in Indonesia by Hadi et al (2018). The oil and aerial part of Teucrium polium belongs to the family of Lamiaceae was collected and examined by Ebadollahi et al (2015), Ebadollahi and Taghinezhad (2020) in Ardebil, Rasht at Iran.…”

Influence of Treating Essential Oils of Canarium Tree Resin on The Level Malondialdehyde (MDA), Protease Activity, Bronchi Histopathology Description and Expression of Tumor Necrosis Alpha Factor (TNF-α) on Asthma Rats (Rattus norvegicus)

“…Sample added a small amount of anhydrous MgSO 4 to remove moisture and flowed nitrogen gas to avoid oxidation [11]. The essential oils of the obtained canarium tree resin were analyzed using GC-MS [12].…”

Antimicrobial Activity and Cytoxicity of Several Sumbawa Traditional Oils (Minyak Sumbawa) in Sumbawa Regency, West Nusa Tenggara, Indonesia

“…Making this oil is a culture to the locals, called Melala. It is usually held in the month of Muharram, where the experts of Melala or locally called sanro will gather and demonstrate their skills in making Minyak Sumbawa using their recipe and expected to have several medicinal benefits [1,2]. The locals believe that Minyak Sumbawa can cure various diseases.…”