Intractable pleural effusion in Kaposi sarcoma following antiretroviral therapy in a Caucasian female infected with HIV

Tajarernmuang, Pattraporn; Fiset, Pierre‐Olivier; Routy, Jean‐Pierre; Beaudoin, Stéphane

doi:10.1136/bcr-2019-233335

Cited by 5 publications

(3 citation statements)

References 32 publications

(30 reference statements)

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“…As already described for other viral co-infections, SARS-CoV-2 can produce the transition of HHV8 from the latent phase to the lytic replication phase by stimulating the release of pro-inflammatory cytokines, leading to severe disease and death [ 32 , 33 , 34 , 35 ].…”

Section: Discussionmentioning

confidence: 99%

Unusual Localization of AIDS-Related Kaposi’s Sarcoma in a Heterosexual Male during the COVID-19 Pandemic: A Case Report

Arbune,

Padurariu-Covit,

Tiutiuca

et al. 2024

TropicalMed

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Kaposi’s sarcoma is an AIDS-defining illness and remains the most frequent tumor arising in HIV-infected patients with multifactorial etiology. We present a case of a 30-year-old Caucasian male with an 18-year history of HIV infection. The patient was presented with a one-week history of fever, non-productive cough, and skin lesions. There was an associated weakness and weight loss in a duration of 6 months. Clinical examination showed fever, generalized lymphadenopathy, lower limb edema, ascites, and violaceous cutaneous eruption comprising patches, plaques, and nodules. He also had a red nodule on the left conjunctiva, as well as on his oral mucosa. His CD4+ count was below 10/mm3 and ARN-HIV viral load was above 100,000 c/mL, in relation to the antiretroviral failure after five drug regimens. The role of co-infections in oncogenesis and the course of Kaposi’s sarcoma were considered in recent studies. Delayed diagnosis of Kaposi’s sarcoma in the present case resulted in a negative impact for this patient during the COVID-19 pandemic.

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Section: Discussionmentioning

confidence: 99%

Unusual Localization of AIDS-Related Kaposi’s Sarcoma in a Heterosexual Male during the COVID-19 Pandemic: A Case Report

Arbune,

Padurariu-Covit,

Tiutiuca

et al. 2024

TropicalMed

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“…The manifestations that can be observed in AITL include generalized lymphadenopathy, hepatomegaly, splenomegaly, systemic B symptoms, rash, polyarthritis, effusions and symptoms related to anemia [ 3 , 5 , 6 ]. The symptoms in the present case together with increased serum IgG may also resemble human herpesvirus 8 (HHV 8)-related conditions such as Kaposi sarcoma [ 29 , 30 ]. However, the serum HIV test was negative and the HHV-8 staining for the lymph node biopsy was negative.…”

Section: Discussionmentioning

confidence: 99%

Plasmacytic Pleural Effusion as a Major Presentation of Angioimmunoblastic T-Cell Lymphoma: A Case Report

Lin

Zhang

et al. 2022

Current Oncology

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Angioimmunoblastic T-cell lymphoma is one of the peripheral T-cell lymphomas. Reactive plasma cells can occasionally be observed in AITL patients’ peripheral blood and bone marrow. Plasmacytic pleural effusion as the presentation of AITL has not been reported before. The mechanisms of plasmacytic pleural effusion are not fully understood. Here we present an 82-year-old male with exuberant plasma cells in his pleural effusion in addition to his peripheral blood and bone marrow aspiration. By presenting this case, we would like to expand the spectrum of disease presentations in AITL and discuss the significance of flow cytometry in the differential diagnosis of pleural effusion. To our knowledge, this is the first case report in the literature, which will be crucial to assist the hematopathologist in accurate diagnosis and treatment.

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“…Hemorrhagic or chylous (milky or chalky) pleural effusions as well as diffuse alveolar hemorrhage have also been associated with pulmonary Kaposi sarcoma 48. However, there have been cases of PLWH who have Kaposi sarcoma without known pulmonary Kaposi sarcoma but with chylous pleural effusions 49, 50. The presence of an effusion in a patient with Kaposi sarcoma should prompt further investigation for a possible diagnosis of concurrent primary effusion lymphoma, multicentric Castleman disease, or both.…”

Section: Clinical Manifestationsmentioning

confidence: 99%

CE: HIV-Associated Kaposi Sarcoma in the Combination Antiretroviral Therapy Era

Mangusan

Ekwede

Widell

2022

AJN, American Journal of Nursing

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:Kaposi sarcoma is a tumor caused by Kaposi sarcoma herpesvirus, also known as human herpesvirus 8. Its occurrence is associated with an immunocompromised state. Kaposi sarcoma that occurs among people living with HIV (PLWH) is known as epidemic Kaposi sarcoma. Despite the decline in HIV-associated complications because of the introduction of combination antiretroviral therapy two decades ago, Kaposi sarcoma continues to affect PLWH worldwide. It affects young African American men more than other age and racial groups and can result in multiorgan dysfunction, leading to short-term and chronic debilitating symptoms as well as death. While some patients with epidemic Kaposi sarcoma are managed as outpatients, others may require higher levels of care and their acuity may fluctuate throughout their life span. Therefore, nurses, regardless of their specialty, may experience caring for a patient with epidemic Kaposi sarcoma at some point in their career. Learning about this condition and the needs of patients who have it will help nurses provide effective care. Here, the authors describe Kaposi sarcoma in general as well as the epidemiology, characteristics, and management of epidemic Kaposi sarcoma. They also describe specific nursing considerations in the care of PLWH who have the disease.

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Intractable pleural effusion in Kaposi sarcoma following antiretroviral therapy in a Caucasian female infected with HIV

Cited by 5 publications

References 32 publications

Unusual Localization of AIDS-Related Kaposi’s Sarcoma in a Heterosexual Male during the COVID-19 Pandemic: A Case Report

Unusual Localization of AIDS-Related Kaposi’s Sarcoma in a Heterosexual Male during the COVID-19 Pandemic: A Case Report

Plasmacytic Pleural Effusion as a Major Presentation of Angioimmunoblastic T-Cell Lymphoma: A Case Report

CE: HIV-Associated Kaposi Sarcoma in the Combination Antiretroviral Therapy Era

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