Intestinal propulsion of a solid non-deformable bolus

Miftahof, Roustem N.; Fedotov, E. M.

doi:10.1016/j.jtbi.2004.12.019

Cited by 16 publications

(5 citation statements)

References 17 publications

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“…A general theoretical model of a solid bolus transported by peristalsis was formulated by Bertuzzi [139]. Miftahof et al described bolus transport models specific to the GI tract to predict contact forces [137,140,141].…”

Section: Gi Muscular Contractionsmentioning

confidence: 99%

“…Calio et al [146] 33 mm 0.25 N cm −1 Terry et al [143] 35 mm 0.9-2.9 N cm −1 Miftahof et al [140] 35 mm 0.15-1.9 N cm −1 capsule than the proximal small bowel, with the primary reason being that the distal small bowel has a smaller diameter than the proximal small bowel [143]. In table 14 the mean values of the contact force measured with different techniques in different works are summarized.…”

Section: Authormentioning

confidence: 99%

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Fundamentals of the gut for capsule engineers

et al. 2020

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The gastrointestinal (GI) tract is a complex environment comprised of the mouth, esophagus, stomach, small and large intestines, rectum and anus, which all cooperate to form the complete working GI system. Access to the GI using endoscopy has been augmented over the past several decades by swallowable diagnostic electromechanical devices, such as pill cameras.Research continues today and into the foreseeable future on new and more capable miniature devices for the purposes of systemic drug delivery, therapy, tissue biopsy, microbiome sampling, and a host of other novel ground-breaking applications. The purpose of this review is to provide engineers in this field a comprehensive reference manual of the GI environment and its complex physical, biological, and chemical characteristics so they can more quickly understand the constraints and challenges associated with developing devices for the GI space. To accomplish this, the work reviews and summarizes a broad spectrum of literature covering the main anatomical and physiological properties of the GI tract that are pertinent to successful development and operation of an electromechanical device. Each organ in the GI is discussed in this context, including the main mechanisms of digestion, chemical and mechanical processes that could impact devices, and GI motor behavior and resultant forces that may be experienced by objects as they move through the environment of the gut.

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Section: Gi Muscular Contractionsmentioning

confidence: 99%

Section: Authormentioning

confidence: 99%

Fundamentals of the gut for capsule engineers

et al. 2020

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“…Various computational models were developed to perform stress analysis (Liao et al, 2006;Liao et al, 2009) and to address intestinal peristalsis (Miftahof and Fedotov, 2005;Miftahof and Akhmadeev, 2007) or muscle contraction (Yassi et al, 2009). There is no paper dealing with numerical simulations of stapling of the intestinal tissues known to the authors.…”

Section: Introductionmentioning

confidence: 99%

Finite element modelling of stapled colorectal end-to-end anastomosis: Advantages of variable height stapler design

Nováček¹,

Tran²,

Klinge³

et al. 2012

Journal of Biomechanics

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“…For example, the myenteron exerts contact pressure (Terry et al, 2012;Miftahof and Fedotov, 2005), the pumping action caused by segmentation and peristalsis of the GI tract generates pressure against the robot fore and aft (Camilleri, 1997), and hydrostatic pressure created by respiration, skeletal muscle movement, and gravity all impart forces on an RCE (Samsom et al, 1998). In addition to these active forces, reactions from the biomechanical response of the small bowel tissue act on the robot (Sacks and Sun, 2003;Higa et al, 2007;Lim et al, 2009).…”

Section: Introductionmentioning

confidence: 99%