As the result of an increasingly globalized and interconnected world, the internationalization of institutions of higher education grew and adopted established and regulated characteristics. An example of this evolution is the creation of the international relations offices (IROs). These sectors are responsible for formalizing collaborations with institutions from other countries to exchange students, academics, and knowledge. A three-dimensional internationalization model -organizational design, student mobility, and scientific production- is used to analyze three Argentine universities with varying degrees of overseas collaborations and their strategies and practices to increase their global presence and impact.